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107 Associated factors to preeclampsia delivery at distinct gestational ages
Abstracts / Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health 6 (2016) 178–252
Conclusion: We found a significant difference between the three groups. Diabetic patients had higher rates that suggest lipotoxicity than others without this comorbidity. Both groups with PE presented higher levels of these markers than the control group. The results indicate that diabetes is directly related to more obese patients, prematurity and inflammatory markers. doi:10.1016/j.preghy.2016.08.188
Clinical science 107 Associated factors to preeclampsia delivery at distinct gestational ages
Preeclampsia in low and middle income countries Mariana Abduch Rahal a, Beatriz Mendes Awni a, Lorena Fernandes Audi a, Isabela Cosimato Ferrari a, Arthur Barros Fontes a, Bárbara Alves Rhomberg a, Natine Fuzihara Rosa a, Stephany Risnic Chvaicer a, Ana Paula De Almeida Righi a, Mariela Degan Barros Battistella a, Barbarah Silveira Penatti a, Lucas Borges De Souza a, Diego Gomes Ferreira a, Rogério Gomes Dos Reis Guidoni a, José Marcelo Garcia a, Nelson Sass b, Francisco Lazaro Pereira De Sousa a (a UNILUS, Santos, SP, Brazil, b UNIFESP, São paulo, SP, Brazil) Introduction: Clinical forms of early and late preeclampsia have different physiopathological mechanisms. Their influence in the most adverse outcomes is related with as earlier the delivery occurs. Objectives: Compare maternal and neonatal outcomes of preeclampsia according to gestational age and identify some maternal characteristics related in each group. Methods: Retrospective study with 71 women, through medical records review, was developed in Guilherme Álvaro HospitalSantos/São Paulo/Brazil (July/2015-April/2016). This study involved pregnant women diagnosed with preeclampsia according to NHBPEP – National High Blood Pressure Education Program (2000), with single and live fetus, regardless of gestational age. Patients were divided into three groups according to delivery gestational age: 20 for early group (<34 weeks), 17 for intermediate group
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(between 34 and 36 6/7 weeks) and 34 for late group (>37 weeks). Exclusion criteria: twin pregnancy and fetal anomalies. Maternal variables: age, gestational age at admission, previous pregnancy history, length of hospital stay, body mass index (BMI), chronic hypertension and diabetes mellitus. Neonatal variables: weight, adequacy of weight for gestational age, height, length of hospital stay, intensive care unit (ICU) admission, Apgar score and respiratory and non-respiratory complications. The study was approved by Guilherme Álvaro Hospital’s ethics and research committee. Statistical comparisons for categorical variables were made using Fisher’s exact test, and Tukey multiple comparisons method for numerical variables. The significance level was p < 0.05. Results: A comparison between the three groups of preeclampsia according to maternal and neonatal outcomes (⁄ = p < 0.05):
Conclusions: Preeclampsia delivery before 34 weeks is more often associated with maternal and neonatal adverse outcomes if compared to deliveries after this gestational age. Patients from early preeclampsia group stay longer in hospital and they are usually nondiabetic. Their newborns present lower weight, smaller height, lower Apgar scores at birth, longer hospital stay (including in ICU) and acute respiratory distress syndrome development. There is a lack of significance in associating maternal age, BMI and chronic hypertension with maternal and neonatal adverse outcomes. doi:10.1016/j.preghy.2016.08.189
Clinical science 108 Are we doing what we can to prevent preeclampsia? Prevention of preeclampsia Thais Travassos Da Silva, Keliany Carla Duarte De Araujo, Nayanne Silva Fonseca, Thais Farias Portugal, Elisa Chalem, Henri Augusto Korkes, Nelson Sass (Hospital Municipal Maternidade Escola Dr. Mário de Moraes Altenfelder Silva – Vila Nova Cachoeirinha, Sao Paulo, SP, Brazil) Introduction: Preeclampsia (PE) is an important cause to maternal and perinatal morbimortality. The usage of acetylsalicylic acid
Conclusion: We found a significant difference between the three groups. Diabetic patients had higher rates that suggest lipotoxicity than others without this comorbidity. Both groups with PE presented higher levels of these markers than the control group. The results indicate that diabetes is directly related to more obese patients, prematurity and inflammatory markers. doi:10.1016/j.preghy.2016.08.188
Clinical science 107 Associated factors to preeclampsia delivery at distinct gestational ages
Preeclampsia in low and middle income countries Mariana Abduch Rahal a, Beatriz Mendes Awni a, Lorena Fernandes Audi a, Isabela Cosimato Ferrari a, Arthur Barros Fontes a, Bárbara Alves Rhomberg a, Natine Fuzihara Rosa a, Stephany Risnic Chvaicer a, Ana Paula De Almeida Righi a, Mariela Degan Barros Battistella a, Barbarah Silveira Penatti a, Lucas Borges De Souza a, Diego Gomes Ferreira a, Rogério Gomes Dos Reis Guidoni a, José Marcelo Garcia a, Nelson Sass b, Francisco Lazaro Pereira De Sousa a (a UNILUS, Santos, SP, Brazil, b UNIFESP, São paulo, SP, Brazil) Introduction: Clinical forms of early and late preeclampsia have different physiopathological mechanisms. Their influence in the most adverse outcomes is related with as earlier the delivery occurs. Objectives: Compare maternal and neonatal outcomes of preeclampsia according to gestational age and identify some maternal characteristics related in each group. Methods: Retrospective study with 71 women, through medical records review, was developed in Guilherme Álvaro HospitalSantos/São Paulo/Brazil (July/2015-April/2016). This study involved pregnant women diagnosed with preeclampsia according to NHBPEP – National High Blood Pressure Education Program (2000), with single and live fetus, regardless of gestational age. Patients were divided into three groups according to delivery gestational age: 20 for early group (<34 weeks), 17 for intermediate group
231
(between 34 and 36 6/7 weeks) and 34 for late group (>37 weeks). Exclusion criteria: twin pregnancy and fetal anomalies. Maternal variables: age, gestational age at admission, previous pregnancy history, length of hospital stay, body mass index (BMI), chronic hypertension and diabetes mellitus. Neonatal variables: weight, adequacy of weight for gestational age, height, length of hospital stay, intensive care unit (ICU) admission, Apgar score and respiratory and non-respiratory complications. The study was approved by Guilherme Álvaro Hospital’s ethics and research committee. Statistical comparisons for categorical variables were made using Fisher’s exact test, and Tukey multiple comparisons method for numerical variables. The significance level was p < 0.05. Results: A comparison between the three groups of preeclampsia according to maternal and neonatal outcomes (⁄ = p < 0.05):
Conclusions: Preeclampsia delivery before 34 weeks is more often associated with maternal and neonatal adverse outcomes if compared to deliveries after this gestational age. Patients from early preeclampsia group stay longer in hospital and they are usually nondiabetic. Their newborns present lower weight, smaller height, lower Apgar scores at birth, longer hospital stay (including in ICU) and acute respiratory distress syndrome development. There is a lack of significance in associating maternal age, BMI and chronic hypertension with maternal and neonatal adverse outcomes. doi:10.1016/j.preghy.2016.08.189
Clinical science 108 Are we doing what we can to prevent preeclampsia? Prevention of preeclampsia Thais Travassos Da Silva, Keliany Carla Duarte De Araujo, Nayanne Silva Fonseca, Thais Farias Portugal, Elisa Chalem, Henri Augusto Korkes, Nelson Sass (Hospital Municipal Maternidade Escola Dr. Mário de Moraes Altenfelder Silva – Vila Nova Cachoeirinha, Sao Paulo, SP, Brazil) Introduction: Preeclampsia (PE) is an important cause to maternal and perinatal morbimortality. The usage of acetylsalicylic acid