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110. Value of the neonatal polysomnography in newborns with less than 1500 g of weight
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Society Proceedings / Clinical Neurophysiology 119 (2008) e99–e164
performance. There was volume in frontal structures a finders decrease, which contrasts with the poor performance of the aMCI group in tests of executive functions. This suggests that volume lost per se does not explain the executive deficit. The episodic memory’s performance in aMCI subjects had a positive correlation with the volume of bilateral temporal structures, including the hippocampus and with the volume of frontal structures in the left hemisphere.
ders. Neonates with inactive and paroxistic layouts showed an unfavorable evolution. It is concluded that neonatal polysomnography was a good indicator of the functional status of the central nervous system in the neonatal period. The results of the EEG, together with the degree of the asphyxia and the evolution of these patients were related. doi:10.1016/j.clinph.2008.04.125
doi:10.1016/j.clinph.2008.04.123
108. Nocturnal polysomnographic studies in a children’s sample with Attention Deficit Hyperactivity Disorder, hyperactivity-type—Y. Alfonsode Armas, A. Alvarez Amador, T. Virue´s Alba, M.C. Rodrı´guez Bowra (Cuba) This paper aimed at describing the sleep disorders found by nocturnal polysomnographic study (PSG) in children with Attention Deficit Hyperactivity Disorder (ADHD) with hyperactivityimpulsivity-type (ADHD/H). We studied 10 children (1 female, 9 males; mean age: 9, 30) who met the DSM-IV criteria of ADHD/H. They were evaluated by a nocturnal polysomnographic study and neurological exploration. All studies were abnormal: 7 (70%) of the children presented periodic movement legs syndrome (PMLS). The sleep architecture of 8 (80%) children with ADHD showed an increase in the percentage of phase III and consequently decreases of phase II of slow sleep. The REM latencies were increased in 7 (70%) of the studied children, whereas the REM percentage was reduced in 5 (50%). Epileptiform-type paroxysms were observed in 40% of the children who presented symptoms of ADHD/H and in 4 (40%) of them parasomnias were demonstrated. The increase of phase III may be related to disorders in noradrenaline and dopamine transmission present in children who suffer from ADHD. Some children with ADHD can have a region of the brain with intense epileptic activity, which does not trigger epileptic seizures but gives rise to behavioral disorders. doi:10.1016/j.clinph.2008.04.124
109. Value of the neonatal polysomnography in newborns with severe asphyxia at birth—Y. Expo´sito Ferna´ndez, M. Contreras Ca´rdenas (Cuba) The objective of this paper was to assess the utility of neonatal Polysomnnography in newborns with severe asphyxia at birth. The usefulness of neonatal polysomnography was evaluated in 73 newborns with severe asphyxia at birth, born at the ‘‘Ame´rica Arias” Gynecologic and Obstetric Hospital, from May 2002 to December 2006. Polysomnographic studies were carried out in the first week of the baby’s life taking under consideration the presence or absence of hypoxic-ischemic encephalopathy. The correlation between neurophysiological and neurological examinations and the follow-up EEG records were analyzed. Kappa index was used to measure the level of agreement among variables. We found a significant correlation between the electroencephalographic results and the degree of asphyxia: i.e. the more severe the asphyxia the more frequent and severe the EEG disor-
110. Value of the neonatal polysomnography in newborns with less than 1500 g of weight—Y. Expo´sito Ferna´ndez, M. Contreras Ca´rdenas (Cuba) The objective of this paper was to assess neonatal Polysomnnography (PSG) in low weight newborns. Neonatal polysomnography was assessed in 66 infants with less than 1500 g of weight at birth and born at ‘‘Ame´rica Arias” Gynecologic and Obstetric Hospital from May 2002 to December 2006. These PSGs were repeated every three months. Neurological evaluations and fontanel ultrasonograms were performed on the day of the PSG studies. The relationship between the PSG results and the causes of neonatal mortality was determined. The PSG in newborns with weight inferior to 1500 g was normal in 83.6%, with slight to moderate disorders in11.5% and with severe disorders in 4.9%. The neurological exam was normal in 77% and abnormal in 11.5%: 7 suspicious cases and 7 pathological cases. A significant relationship was found between the follow-up polysomnographic studies and pathological lesions in dead infants with very low weight at birth. Our results demonstrate that PSG helps to identify subclinical elements in this high risk group. Therefore, PSG could be considered a good indicator of the functional status of the central nervous system and could have prognostic value in high risk groups of infants. doi:10.1016/j.clinph.2008.04.126
111. Prognostic value of brain mapping in the functional recovery of patients with cerebrovascular ischemic disease— F. Torres, I. Delgado, A. Montoya (Cuba) The objective of this study was to establish a functional prognosis of recovery based on the mapping of the brain electric activity in patients with ischemic ictus. A longitudinal, prospective and descriptive study was undertaken at the Juan Bruno Zayas Hospital. A total of 22 patients (mean age: 57.2 years) with atherotrombotic ischemic stroke were studied. Neurophysiological evaluations were made at the seventh day after the ictus. Functional evaluations (Barthel index) were taken at the third and sixth months following ictus. The electrophysiologic brain mapping showed pathological slow activity (theta, delta) and decreased physiologic beta and alpha rhythms activity in cortical ipsilateral and contralateral regions of the ischemic focus. The magnitude of these disorders was closely correlated with the functional recovery. The absence or increase of the energy in the alpha frequency band, associated with the significant increment of energy (magnitude z) in the slow frequency bands constitutes an index of good rehabilitative prognosis. In contrast, the decrement of energy in the alpha band, associated with the increment of
Society Proceedings / Clinical Neurophysiology 119 (2008) e99–e164
performance. There was volume in frontal structures a finders decrease, which contrasts with the poor performance of the aMCI group in tests of executive functions. This suggests that volume lost per se does not explain the executive deficit. The episodic memory’s performance in aMCI subjects had a positive correlation with the volume of bilateral temporal structures, including the hippocampus and with the volume of frontal structures in the left hemisphere.
ders. Neonates with inactive and paroxistic layouts showed an unfavorable evolution. It is concluded that neonatal polysomnography was a good indicator of the functional status of the central nervous system in the neonatal period. The results of the EEG, together with the degree of the asphyxia and the evolution of these patients were related. doi:10.1016/j.clinph.2008.04.125
doi:10.1016/j.clinph.2008.04.123
108. Nocturnal polysomnographic studies in a children’s sample with Attention Deficit Hyperactivity Disorder, hyperactivity-type—Y. Alfonsode Armas, A. Alvarez Amador, T. Virue´s Alba, M.C. Rodrı´guez Bowra (Cuba) This paper aimed at describing the sleep disorders found by nocturnal polysomnographic study (PSG) in children with Attention Deficit Hyperactivity Disorder (ADHD) with hyperactivityimpulsivity-type (ADHD/H). We studied 10 children (1 female, 9 males; mean age: 9, 30) who met the DSM-IV criteria of ADHD/H. They were evaluated by a nocturnal polysomnographic study and neurological exploration. All studies were abnormal: 7 (70%) of the children presented periodic movement legs syndrome (PMLS). The sleep architecture of 8 (80%) children with ADHD showed an increase in the percentage of phase III and consequently decreases of phase II of slow sleep. The REM latencies were increased in 7 (70%) of the studied children, whereas the REM percentage was reduced in 5 (50%). Epileptiform-type paroxysms were observed in 40% of the children who presented symptoms of ADHD/H and in 4 (40%) of them parasomnias were demonstrated. The increase of phase III may be related to disorders in noradrenaline and dopamine transmission present in children who suffer from ADHD. Some children with ADHD can have a region of the brain with intense epileptic activity, which does not trigger epileptic seizures but gives rise to behavioral disorders. doi:10.1016/j.clinph.2008.04.124
109. Value of the neonatal polysomnography in newborns with severe asphyxia at birth—Y. Expo´sito Ferna´ndez, M. Contreras Ca´rdenas (Cuba) The objective of this paper was to assess the utility of neonatal Polysomnnography in newborns with severe asphyxia at birth. The usefulness of neonatal polysomnography was evaluated in 73 newborns with severe asphyxia at birth, born at the ‘‘Ame´rica Arias” Gynecologic and Obstetric Hospital, from May 2002 to December 2006. Polysomnographic studies were carried out in the first week of the baby’s life taking under consideration the presence or absence of hypoxic-ischemic encephalopathy. The correlation between neurophysiological and neurological examinations and the follow-up EEG records were analyzed. Kappa index was used to measure the level of agreement among variables. We found a significant correlation between the electroencephalographic results and the degree of asphyxia: i.e. the more severe the asphyxia the more frequent and severe the EEG disor-
110. Value of the neonatal polysomnography in newborns with less than 1500 g of weight—Y. Expo´sito Ferna´ndez, M. Contreras Ca´rdenas (Cuba) The objective of this paper was to assess neonatal Polysomnnography (PSG) in low weight newborns. Neonatal polysomnography was assessed in 66 infants with less than 1500 g of weight at birth and born at ‘‘Ame´rica Arias” Gynecologic and Obstetric Hospital from May 2002 to December 2006. These PSGs were repeated every three months. Neurological evaluations and fontanel ultrasonograms were performed on the day of the PSG studies. The relationship between the PSG results and the causes of neonatal mortality was determined. The PSG in newborns with weight inferior to 1500 g was normal in 83.6%, with slight to moderate disorders in11.5% and with severe disorders in 4.9%. The neurological exam was normal in 77% and abnormal in 11.5%: 7 suspicious cases and 7 pathological cases. A significant relationship was found between the follow-up polysomnographic studies and pathological lesions in dead infants with very low weight at birth. Our results demonstrate that PSG helps to identify subclinical elements in this high risk group. Therefore, PSG could be considered a good indicator of the functional status of the central nervous system and could have prognostic value in high risk groups of infants. doi:10.1016/j.clinph.2008.04.126
111. Prognostic value of brain mapping in the functional recovery of patients with cerebrovascular ischemic disease— F. Torres, I. Delgado, A. Montoya (Cuba) The objective of this study was to establish a functional prognosis of recovery based on the mapping of the brain electric activity in patients with ischemic ictus. A longitudinal, prospective and descriptive study was undertaken at the Juan Bruno Zayas Hospital. A total of 22 patients (mean age: 57.2 years) with atherotrombotic ischemic stroke were studied. Neurophysiological evaluations were made at the seventh day after the ictus. Functional evaluations (Barthel index) were taken at the third and sixth months following ictus. The electrophysiologic brain mapping showed pathological slow activity (theta, delta) and decreased physiologic beta and alpha rhythms activity in cortical ipsilateral and contralateral regions of the ischemic focus. The magnitude of these disorders was closely correlated with the functional recovery. The absence or increase of the energy in the alpha frequency band, associated with the significant increment of energy (magnitude z) in the slow frequency bands constitutes an index of good rehabilitative prognosis. In contrast, the decrement of energy in the alpha band, associated with the increment of