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1408: Fetal Anomaly Scan: Prenatal Diagnosis & Postnatal Correlation
S210
Ultrasound in Medicine and Biology
Method: A high frequency test object was manufactured by moulding a series of wall-less anechoic pipe structures in a block of agar based TMM with pipe diameters 0.045 – 1.5mm. Each probe was scanned over the surface of the test object. The vertical depth range over which each pipe could be visualised was determined, and plotted as a function of the reciprocal of pipe diameter. The Resolution Integral was calculated for each transducer by measuring the area under the curve obtained by scanning each pipe. Characteristic Resolution (Dr) and Depth of Field (Lr) were also determined from these measurements. Results: Pipe structures with diameters down to 45 micron were successfully manufactured within a novel test object and imaged using probes with frequencies from 12 - 60MHz. Resolution Integrals ranged from 22 (Visualsonics 704 probe 40MHz) to 75 (Philips L17-5 probe) with corresponding Lr/Dr of 4.1 mm/190m and 50mm/670 m respectively. Conclusions: The extended Edinburgh Pipe Phantom was able to successfully determine imaging characteristics of ultrasound probes up to 60MHz.
Volume 35, Number 8S, 2009 hyperextended neck maintained in opisthotonus position. Head was seen in direct continuity with thoracic spine, cervical spine showed gross curvature. Entire spine could not be evaluated in single scan. Baby was delivered by Ceasarean Section. Our case was suspected for Klippel Feil Syndrome, which was confirmed after birth. KF Syndrome results from faulty segmentation along the embryo’s developing axis during 3-8 weeks of gestation. It is manifested by cervical vertebral fusion anomalies causing a short neck with decreased mobility. It may be associated with congenital heart diseases, renal and genital anomalies, sprengel’s shoulder and ocular malformations. Dignosis is made by the presence of short neck associated with opisthotonos (retroflexion of head) and the disorganization of cervical vertebra which is potentially recognized by USG (as seen in our case). Prognosis is poor and complications result from vertebral flexion and include cord compression syndrome, cervical instability and motility impairement. Early diagnosis with termination of pregnancy is offered to these patients before viability.
1410 1408 Fetal Anomaly Scan: Prenatal Diagnosis & Postnatal Correlation Azizul Islam, Square Hospitals Ltd., Bangladesh Background: The purposes of this presentation are 1) To demonstrate correlation of prenatal sonographical findings with postnatal findings. 2) To evaluate the efficacy of sonography in detecting anomalies. 3) To consider the usefulness of USG findings for differentiating lethal and non-lethal fetal anomalies. Materials and Methods: From January to April 2008, 4 patients were enrolled for anomaly scan & underwent details anomaly scan. Examinations were performed with ultrasound alone. Various anomalies may occur at fetal life. Several may appear as a finding of fetal syndrome and shows poor outcome, but the others usually appear as isolated findings and have no clinical significance. Several shows specific inheritance, but the others are sporadic. The accuracy and timely diagnosis of these anomalies is important. Through ultrasound examination of entire fetal organs are mandatory. Results: All the cases showed very close & similar findings of prenatal as well as postnatal. Two died within short interval of birth after delivery at term. This can be terminated at early 2nd Trimester. Other two terminated intime after counseling. Conclusion: Awareness of these potential sonographical findings could help Obstetrician /Clinician making decision & will accurately guide – whether the pregnancy should undergo termination or not. Knowledge of how to use and when to use these very significant and diagnostic tools is important in the modern day management of pregnancies. Key Words: Anomaly Scan, Prenatal & Postnatal Correlation
1409 Klippel Feil Syndrome: A Case Report Sanjay Tomar, Sanjay Pathology Centre, Lakhimpur Kheri. UP, India, India Sakshi Tomar, India Radha Tandon, Tandon Nursing Home, Lakhimpur Kheri, UP, India, India A 35 year old primipara presented for routine USG check up at 32-33 weeks of gestation , USG showed fetus in breech presentation with
Intraoral Sonography: Evaluation of Tongue Tumors Maria Cristina Chammas, Department of Radiology of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Tu´lio A Macedo, Department of Radiology of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Raquel A Moyse´s, Head and Neck Surgery Department of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Rene´ Gerhard, Pathology Department of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Marcelo D Durazzo, Head and Neck Surgery Department of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Cla´udio R Cernea, Head and Neck Surgery Department of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Giovanni G Cerri, Department of Radiology of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Purpose: This survey was undertaken to study tongue tumor thickness measured by intraoral ultrasonography and correlate it with histopathological findings. Subjects and Methods: Twenty patients between 38 and 79 years of age (mean of 59.6), 12 men and 8 women, with TNM-stage tongue carcinomas from T1 to T4a were preoperatively evaluated with IOUS during 20 months. Results: The average thickness measured by IOUS was 1.55 cm(0.54 to 3.50 cm), and by histological sections 1.24 cm(0.30 to 2.5 cm). These values showed significant Pearson correlation(P ⬍ 0.001), and the correlation coefficient (R) was ⫹0.828. The mean discrepancy between IOUS and histological-section measurements was 0.31 cm. It was observed that tumor thickness over the value of 1.75 cm by IOUS and over 1.05 cm by histological sections presented higher correlation with the presence of metastatic cervical lymph nodes. Conclusion: This study suggests that IOUS is capable of identifying the tongue tumor and measuring its thickness with very good histological correlation. Moreover, IOUS gives prognostic information before the surgical treatment.
Ultrasound in Medicine and Biology
Method: A high frequency test object was manufactured by moulding a series of wall-less anechoic pipe structures in a block of agar based TMM with pipe diameters 0.045 – 1.5mm. Each probe was scanned over the surface of the test object. The vertical depth range over which each pipe could be visualised was determined, and plotted as a function of the reciprocal of pipe diameter. The Resolution Integral was calculated for each transducer by measuring the area under the curve obtained by scanning each pipe. Characteristic Resolution (Dr) and Depth of Field (Lr) were also determined from these measurements. Results: Pipe structures with diameters down to 45 micron were successfully manufactured within a novel test object and imaged using probes with frequencies from 12 - 60MHz. Resolution Integrals ranged from 22 (Visualsonics 704 probe 40MHz) to 75 (Philips L17-5 probe) with corresponding Lr/Dr of 4.1 mm/190m and 50mm/670 m respectively. Conclusions: The extended Edinburgh Pipe Phantom was able to successfully determine imaging characteristics of ultrasound probes up to 60MHz.
Volume 35, Number 8S, 2009 hyperextended neck maintained in opisthotonus position. Head was seen in direct continuity with thoracic spine, cervical spine showed gross curvature. Entire spine could not be evaluated in single scan. Baby was delivered by Ceasarean Section. Our case was suspected for Klippel Feil Syndrome, which was confirmed after birth. KF Syndrome results from faulty segmentation along the embryo’s developing axis during 3-8 weeks of gestation. It is manifested by cervical vertebral fusion anomalies causing a short neck with decreased mobility. It may be associated with congenital heart diseases, renal and genital anomalies, sprengel’s shoulder and ocular malformations. Dignosis is made by the presence of short neck associated with opisthotonos (retroflexion of head) and the disorganization of cervical vertebra which is potentially recognized by USG (as seen in our case). Prognosis is poor and complications result from vertebral flexion and include cord compression syndrome, cervical instability and motility impairement. Early diagnosis with termination of pregnancy is offered to these patients before viability.
1410 1408 Fetal Anomaly Scan: Prenatal Diagnosis & Postnatal Correlation Azizul Islam, Square Hospitals Ltd., Bangladesh Background: The purposes of this presentation are 1) To demonstrate correlation of prenatal sonographical findings with postnatal findings. 2) To evaluate the efficacy of sonography in detecting anomalies. 3) To consider the usefulness of USG findings for differentiating lethal and non-lethal fetal anomalies. Materials and Methods: From January to April 2008, 4 patients were enrolled for anomaly scan & underwent details anomaly scan. Examinations were performed with ultrasound alone. Various anomalies may occur at fetal life. Several may appear as a finding of fetal syndrome and shows poor outcome, but the others usually appear as isolated findings and have no clinical significance. Several shows specific inheritance, but the others are sporadic. The accuracy and timely diagnosis of these anomalies is important. Through ultrasound examination of entire fetal organs are mandatory. Results: All the cases showed very close & similar findings of prenatal as well as postnatal. Two died within short interval of birth after delivery at term. This can be terminated at early 2nd Trimester. Other two terminated intime after counseling. Conclusion: Awareness of these potential sonographical findings could help Obstetrician /Clinician making decision & will accurately guide – whether the pregnancy should undergo termination or not. Knowledge of how to use and when to use these very significant and diagnostic tools is important in the modern day management of pregnancies. Key Words: Anomaly Scan, Prenatal & Postnatal Correlation
1409 Klippel Feil Syndrome: A Case Report Sanjay Tomar, Sanjay Pathology Centre, Lakhimpur Kheri. UP, India, India Sakshi Tomar, India Radha Tandon, Tandon Nursing Home, Lakhimpur Kheri, UP, India, India A 35 year old primipara presented for routine USG check up at 32-33 weeks of gestation , USG showed fetus in breech presentation with
Intraoral Sonography: Evaluation of Tongue Tumors Maria Cristina Chammas, Department of Radiology of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Tu´lio A Macedo, Department of Radiology of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Raquel A Moyse´s, Head and Neck Surgery Department of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Rene´ Gerhard, Pathology Department of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Marcelo D Durazzo, Head and Neck Surgery Department of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Cla´udio R Cernea, Head and Neck Surgery Department of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Giovanni G Cerri, Department of Radiology of the Hospital das Clı´nicas da Faculdade de Medicina da Universidade de Sa˜o Paulo, Brazil Purpose: This survey was undertaken to study tongue tumor thickness measured by intraoral ultrasonography and correlate it with histopathological findings. Subjects and Methods: Twenty patients between 38 and 79 years of age (mean of 59.6), 12 men and 8 women, with TNM-stage tongue carcinomas from T1 to T4a were preoperatively evaluated with IOUS during 20 months. Results: The average thickness measured by IOUS was 1.55 cm(0.54 to 3.50 cm), and by histological sections 1.24 cm(0.30 to 2.5 cm). These values showed significant Pearson correlation(P ⬍ 0.001), and the correlation coefficient (R) was ⫹0.828. The mean discrepancy between IOUS and histological-section measurements was 0.31 cm. It was observed that tumor thickness over the value of 1.75 cm by IOUS and over 1.05 cm by histological sections presented higher correlation with the presence of metastatic cervical lymph nodes. Conclusion: This study suggests that IOUS is capable of identifying the tongue tumor and measuring its thickness with very good histological correlation. Moreover, IOUS gives prognostic information before the surgical treatment.