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1701 The projections from the medial superior olive to the inferior colliculus are glycinergic in the mole
S214
17. Auditory
1701 Department
System
The projections from the medial superior olive to the inferior colliculus are glycinergic in the mole. of Anatomy, School of Medicine, Kanazawa University, Kanazawa 920, Japan
MOT01 KUDO The projections from the medial superior olive (MSO) to the inferior colliculus (IC) are said to be excitatory, probably glutamatergic, in the cat, rat and guinea pig. We here report hat the MSO-IC projections are glycinergic in the mole, a subterranean mammal with a pressure difference (bird-ear) type receiver. An polyclonal antibody to glycine-glutalaldehyde-BSA was used for immunohistochemistry. Glycine immuno-positive neurons were abundantly seen in the MS0 of the mole. 3H-glycine was also used as another selective marker, since retrogradely labeled neurons from the IC injection are believed to use glycine as a transmitter. SH-glycine positive neurons were found in the MSO, where almost all neurons projecting to the IC were heavily labeled. In other superior olivary nuclei such as the medial trapezoid body (MTB), the superior paraolivary (SPN) and the lateral (LSO), a distinctive pattern of glycinergic cell distribution in common with other mammals is also evidenced in the mole.
1702
LINEAR AND NONLINEAR ENCODING PATTERNS LUS IN GUINEA PIG AUDITORY CORTEX Advanced Research Laboratory, Hitachi, Ltd.
FOR A TWO-TONE
STIMU-
KOHYU FUKUNISHI, TSUYOSHI MIYASHITA, RYO TOKIOKA, NOBUYUKI MURAI Neural responses to a synthesized sound with two tone bursts were analyzed in the Guinea pig auditory cortex. The spatial response patterns, which were imaged optically on 3mmx3mm in the auditory cortex (field A), to each tone and the synthesized tone were compared. The cortical response area to the synthesized sound with two tones as 2.11 kHz and 9.11 kHz subtracted by the response area to either tone almost overlaped to the response area to another tone. However, the response area to the synthesized sound with two tones of low frequencies as 1.11 kHz and 3.11 kHz overlapped to the response area to the lower frequency tone (1.11 kHz). As the results, animals can hear only the lower frequency tone from a two-tone sound with both low frequencies of lower than about 5 kHz (Nonlinear response), but can hear both tones from a two-tone sound with other frequency combinations (Linear response). Thus an encoding structure of a complex sound in an animal auditory cortex has clarified.
17. Auditory
1701 Department
System
The projections from the medial superior olive to the inferior colliculus are glycinergic in the mole. of Anatomy, School of Medicine, Kanazawa University, Kanazawa 920, Japan
MOT01 KUDO The projections from the medial superior olive (MSO) to the inferior colliculus (IC) are said to be excitatory, probably glutamatergic, in the cat, rat and guinea pig. We here report hat the MSO-IC projections are glycinergic in the mole, a subterranean mammal with a pressure difference (bird-ear) type receiver. An polyclonal antibody to glycine-glutalaldehyde-BSA was used for immunohistochemistry. Glycine immuno-positive neurons were abundantly seen in the MS0 of the mole. 3H-glycine was also used as another selective marker, since retrogradely labeled neurons from the IC injection are believed to use glycine as a transmitter. SH-glycine positive neurons were found in the MSO, where almost all neurons projecting to the IC were heavily labeled. In other superior olivary nuclei such as the medial trapezoid body (MTB), the superior paraolivary (SPN) and the lateral (LSO), a distinctive pattern of glycinergic cell distribution in common with other mammals is also evidenced in the mole.
1702
LINEAR AND NONLINEAR ENCODING PATTERNS LUS IN GUINEA PIG AUDITORY CORTEX Advanced Research Laboratory, Hitachi, Ltd.
FOR A TWO-TONE
STIMU-
KOHYU FUKUNISHI, TSUYOSHI MIYASHITA, RYO TOKIOKA, NOBUYUKI MURAI Neural responses to a synthesized sound with two tone bursts were analyzed in the Guinea pig auditory cortex. The spatial response patterns, which were imaged optically on 3mmx3mm in the auditory cortex (field A), to each tone and the synthesized tone were compared. The cortical response area to the synthesized sound with two tones as 2.11 kHz and 9.11 kHz subtracted by the response area to either tone almost overlaped to the response area to another tone. However, the response area to the synthesized sound with two tones of low frequencies as 1.11 kHz and 3.11 kHz overlapped to the response area to the lower frequency tone (1.11 kHz). As the results, animals can hear only the lower frequency tone from a two-tone sound with both low frequencies of lower than about 5 kHz (Nonlinear response), but can hear both tones from a two-tone sound with other frequency combinations (Linear response). Thus an encoding structure of a complex sound in an animal auditory cortex has clarified.