1.P.329 Cardiovascular risk factors in the Spanish working population

1.P.329 Cardiovascular risk factors in the Spanish working population

Monday 86 1 P Lid 327 6 October 1997: Posters Epidemiology Monthly variations for cholesterolemia and trigiyceridemia a Brazilian population E.C...

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Monday 86 1 P

Lid

327

6 October 1997: Posters Epidemiology

Monthly variations for cholesterolemia and trigiyceridemia a Brazilian population

E.C. Fruia’, A.A. Varriano’, E. Guelli’, H.C.F. Oliveira2, L.N. Castilho’ Depts. of ‘Clinical Parhology, School of Medicine; 2Physiology and Biophysics, Biology Institute, University of Campinas, S.I?, Brazil

in

Most levels. April; higher changes within

(C)

of the population had their C (53%) and T (74%) at the desirable The highest percentage difference for C was 5% between January and for T it was 8% between June and September. The triglyceridemia was in the colder months of the year (5, 6, 7) in Brazil. Probably dietary were the main factors responsible for the month-to-month differences this population.

11 .P.328

E.C. de Faria’, M.L.P.S. Oliveira’, E. Guelli’, A.A. Varriano’, H.C.F. Oliveira’, L.N. Castilho’ ‘Depts. of Clinical Pathology, School of Medicine; 2Physiology and Byophysics, Biology Institute, University of Campinas, S.I?, Brazil Hypercholesterolemia, family history of premature coronary heart disease (CHD), hypertension, cigarette smoking, diabetes, sedentary lifestyle and obesity are risk factors for CHD that operate in men and women. Eight hundred and sixty-nine volunteers, aged 20 to 82 years, with body mass indeces varying from 15.60 to 41.15 kg!m2, 47.18% females and 52.82% males, from 4 different areas of Campinas, SBo Paulo, Brazil, had their blood total cholesterol measured by enzymatic method through reflectance photometry (Reflotron, Merck Sharp-Dome) over a 7 day period. They also answered questions related to the presence of several CHD risk factors. The data were analysed with the SAS software. The frequency distribution of the risk factors in percentages and in numbers of individuals is shown below.

Cholesterol > 200 mg/dL Family history premature CHD Hypertension Cigarette smoking Diabetes Sedentary lifestyle Obesity

Percentage Frequency Total (n)

Men (II)

women (II)

41.31 (359) 45.22 (393) 22.55196) 21.05 (183) 3.79 (33) 48.90 (425) 21.51 (187)

37.01 (171) 35.16 (160) 18.64 (85) 23.86 (110) 3.48 (16) 45.99 (212) 15.65 (72)

45.74 ( 188) 57.39 (233) 27.07 (111) 17.80 (73) 4.14 (17) 51.95 (213) 27.98 (115)

Cardiovascular risk factors in the Spanish working population M.I. AlgarIn.

F. Fabiani.

and working

Hypercholesterolemia, family history of premature CHD, and sedentary lifestyle are the most common risk factors in this population. The frequency of diabetes was the lowest. Although these CHD risk factors are shared by both sexes, in this Brazilian population all the risk factors had a higher frequence among women; only cigarette smoking showed a higher frequency among men. Even though the relative strength of different risk factors is different between the sexes, CHD risk should not be neglected in women.

group

of the INSHT

Purpose of the Study: The study is intended to asess the risk of being affected by a cardiovascular disease (CD) in the Spanish working population, and also for determinating the geographical distribution of the risk, so as priorizing actions on some determinated risk factors (RF) and unifying criteria for the active studies on the working population to be developed in the future. Methods: Sampling design - Working population, stratifying by sex, age and geographical distribution (error equal to 5% for a confidence level of 95%). Risk factors - The following issues were considered: previous cardiovascular diseases, age, sex, obesity, smoking, alcohol, cholesterol (total and HDL), triglycerids, high blood pressure, electrocardiographical disorders, glucose, and uric acid. Data collection and quality control - Personalized questionnaire, analitical quality control, pilot study, and treatment of the data by a certified computer programme. Results: They are presented in the following terms: depending upon the studied parameters, and depending upon the geographical location (north, center an south). Wide differences in the prevalence of the RF are observerd if compared with other studies on the working and general population. The risk of suffering a CD assessed for the population is 47.6%, being specially significant the southern area of Spain (Sevilla and Murcia). Conclusions: - Taking into account the risk of suffering a CD determinated for the working population, some criteria and strategies are fixed appointing to the primary and second prevention. - Taking into account the great variability in the results found in the works elaborated within our scientific community, some actions tending to unify criteria relating to establish the limits for the normality and abnormality of the different RF are proposed.

1P ILZI

330

Anthropometry and lipoproteins-related young adult males in Taiwan

Y.A. Ding, N.F. Chu, T.W. Wang, C.C. Lin. Department Tri-Service General Hospital, National Defense Medical Taiwan, ROC

1 Is the population distribution of risk factors for coronary heart die diierent for men and women?

Risk factors for CHD

1 P 329

A. de la lglesia, &villa, Spain

.

Serum cholesterol concentration has been reported to be higher in winter than in summer and triglyceridemia higher in summer. A large number of patients (7735), hospital&d and ambulatory, from the State University Hospital of Campinas, Sb Paulo, had their serum levels of cholesterol (C) and triglyceride (T) measured by enzymatic methods in the analyser Selectra-Merck, over a period of 12 months. The results for C and/or T 5 200 mg/dL, n = 4101 (C) and n = 5742 (T), were anaysed using the SAS and Origin programs. The C and T (x f SD) for the months l-12 (January-December) are shown below.

L-%LIJm

I

characteristics of of Internal Medicine, Center; Taipei,

The aim of this study was to investigate the prevalence of obesity and the lipoprotein-related characteristics among young male adults in the Taiwan area. After cluster sampling, a cross-sectional survey with a total of 936 males (mean age 20, 18-24) were enrolled. The prevalence of obesity was 9.6% by the criterion of body weight greater than 20% of ideal body weight, or 12.6% by the criterion of body mass index (BMI) greater than 25. The obese subjects had significantly higher serum total cholesterol (CHOL), triglyceride (TG) and apolipoprotein B (apo B) and lower high density lipoprotein-cholesterol (HDL-C) levels than the non-obese. The apo Al levels were 141.3 and 141.9 mg/dl and the lipoprotein [a] (Lp[a]) were 17.4 and 17.1 mg/dl in obese and non-obese respectively, the difference being not statistically significant. Pearson correlation coefficients of body weight, body height, BMI, waist circumference, hip circumference and waist-hip ratio (WHR) to lipoprotein variables showed that both BMI and WHR are positively correlated with CHOL, TG and apo B, but negatively correlated with HDL-C. Furthermore, the lipoprotein variables were better correlated with BMI than WHR in lean subjects (BMI < 25). However, this phenomenon was quite different in obese (BMI z 25) subjects, where the WHR was more highly correlated with lipoprotein variables than with BMI. The prevalence of obesity is slightly higher than reported in previous studies in Taiwan. The obese subjects had CHOL, TG, and apo B and lower HDL-C levels than non-obese subjects. The BMI was more highly correlated with lipoprotein variables than was WHR in lean subjects, but the WHR was more highly correlated with lipoprotein variables than was BMI in obese subjects.

I 1 P.331

Total cholesterol distributions and time trends in the populations of the WHO-MONICA project

M. Ferrario, D. G&netter, K. Kuulasmaa, R. Pole&e, V. Moltchanov, M.L. Chatenoud, J. Yamell. on behalf of the WHO MONICA Project; University of Milan, Monza: Institute for Clinical and Experimental Medicine, Prague; National Public Health Institute, Helsinki and University of Belfast, Belfast, Italy Sporadic data are currently available on reliable estimates of Total Cholesterol (TC) distributions and trends over time, to be used for worldwide comparisons

I Ith International

Symposium

on Atherosclerosis,

Paris,

October

1997