- Email: [email protected]
217. Differences on GTV and PTV dose coverage for lung tumor stereotactic cyberknife treatments using Raytracing and MC algorithm: A retrospective study
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Abstracts / Physica Medica 56 (2018) 133–278
can be found, on the level of peak to entrance ratio for idealized geometries, as well as in critical organs sparing in test patient plans cases. Conclusions. MIBO can provide in selected conditions an indication for an alternative treatment, where combination of different ions lead to better therapeutic ratio as compared to any of the single ion plans. The present approach has been proposed and accepted to be tested on in vitro phantoms at the MIT ion beam facility (Marburg, Germany) which provides different ions in a fast source switching mode.
References 1. Tinganelli W et al.. Kill-painting of hypoxic tumours in charged particle therapy. Sci Rep 2015;5:17016. 2. Sokol O et al.. Oxygen beams for therapy: advanced biological treatment planning and experimental verification. Phys Med Biol 2017;62:7798. https://doi.org/10.1016/j.ejmp.2018.04.227
Methods. The patients were treated with CyberKnife Linear accelerator in a ipofractionated radiotherapy regimen. We first divided the patients in two groups depending on tumor localization ( peripheral and central lesions) and then, in each group, we created three volume classes (GTV610 cc; 10 cc
217. Differences on GTV and PTV dose coverage for lung tumor stereotactic cyberknife treatments using Raytracing and MC algorithm: A retrospective study M. Mormile a, L. Iadanza b, C. Zambella c, P. Muto c a
ASL NA1 Centro, PO del Mare, UOC Radioterapia, Napoli, Italy Azienda Ospedaliera G. Rummo, UOC Radioterapia, Benevento, Italy c Istituto Nazionale dei Tumori di Napoli, Napoli, Italy b
Purpose. The aim of this work is to compare the coverage of GTVs and corresponding PTVs lung lesions in 86 patients treated at the National Tumor Institute of Naples ‘‘G. PASCALE”, between January 2015 and June 2016, with CyberKnife using two different algorithms (Ray-tracing and MonteCarlo) with the same beams and the same number of monitor units per beam.
218. Jarvik2000 and radiotherapy. Irradiation with high-energy photon beams and first results R. Giménez De Lorenzo a,d, R. Navarra a,c, D. Marinelli b, N. Adorante a, S. Giancaterino a, D. Genovesi a, G. Di Giammarco b, M.D. Falco a a
Department of Radiation Oncology, SS. Annunziata Hospital, University ‘‘G. d’Annunzio”, Chieti, Italy b Department of Cardiac Surgery, SS. Annunziata Hospital, University ‘‘G. d’Annunzio”, Chieti, Italy c Department of Neuroimaging and Cognitive Science, University ‘‘G. d’Annunzio”, Chieti, Italy d Department of Radiation Oncology, Azienda Ospedaliera-Universitaria ‘‘Ospedali Riuniti”, Foggia, Italy
Abstracts / Physica Medica 56 (2018) 133–278
can be found, on the level of peak to entrance ratio for idealized geometries, as well as in critical organs sparing in test patient plans cases. Conclusions. MIBO can provide in selected conditions an indication for an alternative treatment, where combination of different ions lead to better therapeutic ratio as compared to any of the single ion plans. The present approach has been proposed and accepted to be tested on in vitro phantoms at the MIT ion beam facility (Marburg, Germany) which provides different ions in a fast source switching mode.
References 1. Tinganelli W et al.. Kill-painting of hypoxic tumours in charged particle therapy. Sci Rep 2015;5:17016. 2. Sokol O et al.. Oxygen beams for therapy: advanced biological treatment planning and experimental verification. Phys Med Biol 2017;62:7798. https://doi.org/10.1016/j.ejmp.2018.04.227
Methods. The patients were treated with CyberKnife Linear accelerator in a ipofractionated radiotherapy regimen. We first divided the patients in two groups depending on tumor localization ( peripheral and central lesions) and then, in each group, we created three volume classes (GTV610 cc; 10 cc
217. Differences on GTV and PTV dose coverage for lung tumor stereotactic cyberknife treatments using Raytracing and MC algorithm: A retrospective study M. Mormile a, L. Iadanza b, C. Zambella c, P. Muto c a
ASL NA1 Centro, PO del Mare, UOC Radioterapia, Napoli, Italy Azienda Ospedaliera G. Rummo, UOC Radioterapia, Benevento, Italy c Istituto Nazionale dei Tumori di Napoli, Napoli, Italy b
Purpose. The aim of this work is to compare the coverage of GTVs and corresponding PTVs lung lesions in 86 patients treated at the National Tumor Institute of Naples ‘‘G. PASCALE”, between January 2015 and June 2016, with CyberKnife using two different algorithms (Ray-tracing and MonteCarlo) with the same beams and the same number of monitor units per beam.
218. Jarvik2000 and radiotherapy. Irradiation with high-energy photon beams and first results R. Giménez De Lorenzo a,d, R. Navarra a,c, D. Marinelli b, N. Adorante a, S. Giancaterino a, D. Genovesi a, G. Di Giammarco b, M.D. Falco a a
Department of Radiation Oncology, SS. Annunziata Hospital, University ‘‘G. d’Annunzio”, Chieti, Italy b Department of Cardiac Surgery, SS. Annunziata Hospital, University ‘‘G. d’Annunzio”, Chieti, Italy c Department of Neuroimaging and Cognitive Science, University ‘‘G. d’Annunzio”, Chieti, Italy d Department of Radiation Oncology, Azienda Ospedaliera-Universitaria ‘‘Ospedali Riuniti”, Foggia, Italy