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241 PERIURETHRAL INJECTION OF AUTOLOGOUS ADIPOSE-DERIVED STEM CELLS FOR THE TREATMENT OF STRESS URINARY INCONTINENCE IN PATIENTS UNDERGOING RADICAL PROSTATECTOMY: OUTCOME OF PRELIMINARY CLINICAL TRIAL
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241
PERIURETHRAL INJECTION OF AUTOLOGOUS ADIPOSE-DERIVED STEM CELLS FOR THE TREATMENT OF STRESS URINARY INCONTINENCE IN PATIENTS UNDERGOING RADICAL PROSTATECTOMY: OUTCOME OF PRELIMINARY CLINICAL TRIAL
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Q RIWKHOHVLRQVFDQEHIRXQGLQWKHORZHU Q LQWKHXSSHU FLUFXPIHUHQFHRIWKHVSKLQFWHU$FRQFRPLWDQWWKHUDS\UHTXLULQJVWULFWXUHDVVRFLDWHG ZLWKWKHVSKLQFWHUZDVGHWHFWHGLQDOOSDWLHQWV Q Q RIWKHSDWLHQWV SUHVHQWHGZLWKDQDQDVWRPRVLVVWULFWXUH Q KDGEODGGHUQHFNVWHQRVLV DQG Q VKRZHGSHQLOHXUHWKUDOVWULFWXUHVRUPRUHV\QFKURQLFVWULFWXUH ORFDOLVDWLRQVZHUHVHHQLQ Q RIWKHSDWLHQWV Conclusions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ᚑFXOWLHVFRQFHUQLQJWKHOHDUQLQJFXUYHIRUODSDURVFRSLF WHFKQLTXHV
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URODYNAMIC EFFECTS OF ADJUSTABLE CONTINENCE THERAPY FOR MEN WITH STRESS URINARY INCONTINENCE (SUI) AFTER RADICAL PROSTATECTOMY (RP)
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EVALUATION AND CLASSIFICATION OF SPHINCTER LESIONS DUE TO RADICAL PROSTATECTOMY (RP)
(LPHU&4XDVW6*HUXOOLV+2WWR7&HQWHUIRU,QQRYDWLYH7HFKQLTXHVLQ 0HGLFLQH Lukas Hospital, Dept. of Urology, Neuss, Germany Introduction & Objectives: *UDGH ,,, XULQDU\ VWUHVV LQFRQWLQHQFH 86, DV FRQVHTXHQFH RI WKH GDPDJH RI WKH H[WHUQDO XUHWKUDO VSKLQFWHU LV D UDUH EXWW\SLFDOFRPSOLFDWLRQDIWHU53)URP2FWREHUXQWLO6HSWHPEHU SDWLHQWVIURPGLᚎHUHQW*HUPDQKRVSLWDOVZHUHVHHQDWRXULQVWLWXWLRQIRUJUDGH ,,,86, Material & Methods: $SDUW IURP PHGLFDO KLVWRU\ DQG FOLQLFDO H[DPLQDWLRQ GLDJQRVWLFWRROVZHUHDVIROORZV 3URWRFRORIPLFWXULWLRQ3$'7HVW8URG\QDPLFV 8UHWKURF\VWRVFRS\ Results: 0HGLDQDJHRIWKHSDWLHQWVZDV\HDUV,QFRQWLQHQFHSHUVLVWHGVLQFH PRQWKV UDQJH 0HGLFDO FDUH FRQFHUQLQJ 86, FRQWDLQHG WKH XVH RI GLDSHUV DQG XULQDU\ FRQGRPV 6XᚑFLHQW PLFWXULWLRQ YROXPH FRXOG EH UHDFKHG LQ KRUL]RQWDO SRVLWLRQ RQO\ 8URG\QDPLFV UHYHDOHG UHGXFHG EODGGHU FDSDFLW\ DQG UHVLGXDOIUHH YRLGLQJ Q RI WKH SDWLHQWV KDG XQGHUJRQH UHWURSXELF 53 Q ODSDURVFRSLF RU URERWDVVLVWHG 53 XQG Q SHULQHDO 53 8UHWKURF\VWRVFRSLFDOO\PRUSKRORJLFOHVLRQVRIWKHH[WHUQDOXUHWKUDOVSKLQFWHUFRXOG EHVHHQLQDOOSDWLHQWV Q 7KHHYDOXDWLRQRIWKHOHVLRQVFDQEHFODVVLᚏHGDV IROORZV ,QRIWKHFDVHV Q WKHVSKLQFWHUZDVGDPDJHGE\DQDVWRPRVLV VXWXUHV7UDQVVHFWLRQLQFLVLRQRIWKHVSKLQFWHUFRXOGEHREVHUYHGLQ Q
Conclusions: 7KHLQFUHDVHGXUHWKUDOUHVLVWDQFHKDGQRGLVDGYDQWDJHRXVHᚎHFWV RQ WKH EODGGHU VWRUDJH IXQFWLRQ 'HWUXVRU RYHUDFWLYLW\ DQG EODGGHU FRPSOLDQFH VHHPHG WR LPSURYH EXW QXPEHUV ZHUH WRR VPDOO IRU D XVHIXO FRPSDULVRQ 7KH 3UR$&7 LPSODQW FXUHG RU VLJQLᚏFDQWO\ LPSURYHG 68, DIWHU 53 ZLWKRXW FDXVLQJ LQIUDYHVLFDOREVWUXFWLRQLQPRVWSDWLHQWV
Eur Urol Suppl 2010;9(2):105
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PERIURETHRAL INJECTION OF AUTOLOGOUS ADIPOSE-DERIVED STEM CELLS FOR THE TREATMENT OF STRESS URINARY INCONTINENCE IN PATIENTS UNDERGOING RADICAL PROSTATECTOMY: OUTCOME OF PRELIMINARY CLINICAL TRIAL
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243
URODYNAMIC EFFECTS OF ADJUSTABLE CONTINENCE THERAPY FOR MEN WITH STRESS URINARY INCONTINENCE (SUI) AFTER RADICAL PROSTATECTOMY (RP)
%ORN%)0*URHQ- Erasmus Medical Center, Dept. of Urology, Rotterdam, The Netherlands Introduction & Objectives: 3UR$&7LPSODQWDWLRQLVDPLQLPDOO\LQYDVLYHSURFHGXUH IRUWKHWUHDWPHQWRI68,DIWHU53*RRGFOLQLFDOUHVXOWVKDYHEHHQUHSRUWHGEXWWKH PHFKDQLVP RI DFWLRQ LV DV \HW XQFOHDU :H HYDOXDWHG WKH XURG\QDPLF HᚎHFWV RI 3UR$&7DQGSDLGVSHFLDODWWHQWLRQWRXUHWKUDOUHVLVWDQFHGXULQJYRLGLQJDVLWPLJKW EHK\SRWKHVL]HGWKDWLPSURYHPHQWRIFRQWLQHQFHLVDFFRPSDQLHGE\LQIUDYHVLFDO REVWUXFWLRQ Material & Methods: $ PXWLFKDQQHO XURG\QDPLRF H[DPLQDWLRQ LV SDUW RI WKH HYDOXDWLRQDIWHUDQRSWLPDOFOLQLFDOUHVXOWKDVEHHQREWDLQHG7KHUHVXOWVRISRVWRS XURG\QDPLF VWXGLHV ZHUH FRPSDUHG ZLWK WKRVH RI WKH SUHRS RQHV 7KH VWXGLHV LQFOXGHG IUHH XURᚐRZPHWU\ PHGLXP UDWH POPLQ ᚏOOLQJ F\VWRPHWULHV DQG SUHVVXUHᚐRZVWXGLHV7KHSDUDPHWHUVFRQVLGHUHGDUHOLVWHGLQWKHWDEOH SDLUHGW WHVWZDVXVHGIRUVWDWLVWLFDOFRPSDULVRQ Results: 7KH VHULHV RI EDOORRQ DGMXVWPHQWV WR REWDLQ DQ RSWLPDO UHVXOW FXUH RU VLJQLᚏFDQW LPSURYHPHQW ZDV FRPSOHWHG LQ PHQ ZLWK D 6WDPH\ JUDGH DQGZLWK6WDPH\DJHs\HDUV 7KHSRVWRSXURG\QDPLFVWXG\ZDVGRQH s ZHHNV DIWHU LPSODQW 7KH PHDQ EDOORRQ YROXPH ZDV sPO UHVXOWLQJ IURPsDGMXVWPHQWV7KHWDEOHVXPPDULVHVWKHUHVXOWVRIWKHVWXG\ $VPLJKW EHH[SHFWHG%22,FRQVLGHUDEO\LQFUHDVHG9RLGLQJRIPRVWSDWLHQWVFKDQJHGIURP WKHXQREVWUXFWHGWRWKHHTXLYRFDODUHDLQWKHSURYLVLRQDO,&6QRPRJUDP ᚏJXUH %ODGGHU9RLGLQJ(ᚑFLHQF\GHFUHDVHGVLJQLᚏFDQWO\LQWKHSUHVVXUHᚐRZVWXGLHVSRVW YRLGUHVLGXDODIWHUIUHHXURᚐRZPHWU\GLGQRWFRQVLGHUDEO\LQFUHDVHLQPRVWPHQ
EVALUATION AND CLASSIFICATION OF SPHINCTER LESIONS DUE TO RADICAL PROSTATECTOMY (RP)
(LPHU&4XDVW6*HUXOOLV+2WWR7&HQWHUIRU,QQRYDWLYH7HFKQLTXHVLQ 0HGLFLQH Lukas Hospital, Dept. of Urology, Neuss, Germany Introduction & Objectives: *UDGH ,,, XULQDU\ VWUHVV LQFRQWLQHQFH 86, DV FRQVHTXHQFH RI WKH GDPDJH RI WKH H[WHUQDO XUHWKUDO VSKLQFWHU LV D UDUH EXWW\SLFDOFRPSOLFDWLRQDIWHU53)URP2FWREHUXQWLO6HSWHPEHU SDWLHQWVIURPGLᚎHUHQW*HUPDQKRVSLWDOVZHUHVHHQDWRXULQVWLWXWLRQIRUJUDGH ,,,86, Material & Methods: $SDUW IURP PHGLFDO KLVWRU\ DQG FOLQLFDO H[DPLQDWLRQ GLDJQRVWLFWRROVZHUHDVIROORZV 3URWRFRORIPLFWXULWLRQ3$'7HVW8URG\QDPLFV 8UHWKURF\VWRVFRS\ Results: 0HGLDQDJHRIWKHSDWLHQWVZDV\HDUV,QFRQWLQHQFHSHUVLVWHGVLQFH PRQWKV UDQJH 0HGLFDO FDUH FRQFHUQLQJ 86, FRQWDLQHG WKH XVH RI GLDSHUV DQG XULQDU\ FRQGRPV 6XᚑFLHQW PLFWXULWLRQ YROXPH FRXOG EH UHDFKHG LQ KRUL]RQWDO SRVLWLRQ RQO\ 8URG\QDPLFV UHYHDOHG UHGXFHG EODGGHU FDSDFLW\ DQG UHVLGXDOIUHH YRLGLQJ Q RI WKH SDWLHQWV KDG XQGHUJRQH UHWURSXELF 53 Q ODSDURVFRSLF RU URERWDVVLVWHG 53 XQG Q SHULQHDO 53 8UHWKURF\VWRVFRSLFDOO\PRUSKRORJLFOHVLRQVRIWKHH[WHUQDOXUHWKUDOVSKLQFWHUFRXOG EHVHHQLQDOOSDWLHQWV Q 7KHHYDOXDWLRQRIWKHOHVLRQVFDQEHFODVVLᚏHGDV IROORZV ,QRIWKHFDVHV Q WKHVSKLQFWHUZDVGDPDJHGE\DQDVWRPRVLV VXWXUHV7UDQVVHFWLRQLQFLVLRQRIWKHVSKLQFWHUFRXOGEHREVHUYHGLQ Q
Conclusions: 7KHLQFUHDVHGXUHWKUDOUHVLVWDQFHKDGQRGLVDGYDQWDJHRXVHᚎHFWV RQ WKH EODGGHU VWRUDJH IXQFWLRQ 'HWUXVRU RYHUDFWLYLW\ DQG EODGGHU FRPSOLDQFH VHHPHG WR LPSURYH EXW QXPEHUV ZHUH WRR VPDOO IRU D XVHIXO FRPSDULVRQ 7KH 3UR$&7 LPSODQW FXUHG RU VLJQLᚏFDQWO\ LPSURYHG 68, DIWHU 53 ZLWKRXW FDXVLQJ LQIUDYHVLFDOREVWUXFWLRQLQPRVWSDWLHQWV
Eur Urol Suppl 2010;9(2):105