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249
Posters
249. Comparison of caudal epidural anesthesia with lidocaine-distilled water and lidocaine-mgSO4 mixture in cattle S.N. Dehghani, Z. Shafiei, A.S. Bigham [email protected] Department of Surgery and Radiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran Background: The most frequently used epidural anesthetic is lidocaine; mepivacaine, bupivacaine, and procaine are also used (Day and Skarda 1991). With the exception of bupivacaine, this group of agents provides analgesia of relatively short duration and may necessitate re-administration of the agent to allow completion of the procedure. Objective: To directly compare the time of onset and duration of analgesia produced by a Lidocaine-MgSO4 combination with that produced by Lidocaine-Distilled water administration in the caudal epidural space of dairy cattle. Animal: Five adult (4.6 ⫾ 0.5 years of age) dairy cows (480.0⫾71 kg). Methods: Caudal epidural anesthesia was produced in all cows with 2% lidocaine (0.22 mg/kg) with 1 ml distilled water and two weeks later repeated by lidocaine (0.22 mg/kg) with 1 ml of 10% MgSO4. Time to onset, duration and cranial spread of analgesia were recorded. Heart rate, Respiratory rate and body temperature were recorded. Results: Significant difference (p⬍0.05) was noted for time (mean ⫾ SEM) of onset of analgesia between Lidocaine-Distilled water (2.04 ⫾ 0.14 min) and Lidocaine-MgSO4 (4.70 ⫾ 0.20 min) that onset of analgesia following Lidocaine-MgSO4 was longer than Lidocaine-Distilled water. Lidocaine-MgSO4 produced analgesia of significantly longer duration (185.0 ⫾ 5.13 min) than that of Lidocaine - Distilled water (49.2 ⫾ 4.53 min). There were no significant differences in HR, RR, and body temperature between Lidocaine-Distilled water and Lidocaine-MgSO4. Conclusion: The combination of Lidocaine-MgSO4 produces analgesia longer than Lidocaine-Distilled water.
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Peripheral Nerve Block
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252. Postoperative analgesic effect of continuous fascia iliaca compartment block after femoral osteotomy in pediatrics with cerebral palsy A.Y. Oh, M.J. Yun, H.S. Kim, Y.S. Oh [email protected] Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Sungnam, Kyounggi, South Korea Background: To report a preliminary analysis of prospectively recorded data in 6 children with cerebral palsy in whom continuous fascia iliaca compartment block and single fascia iliaca compartment block on each lower limb were used for postoperative pain control following bilateral femur derotational osteotomy. Methods: Under general anesthesia, perineural catheters for continuous fascia iliaca compartment block were inserted on one lower limb and single fascia iliaca compartment block(0.25% bupivacaine 1 mg/kg) was done on another lower limb. Continuous fascia iliaca compartment block was done with a same bolus dose as the single block and a continuous infusion of 0.125% bupivacaine(0.2ml/kg/ hr) for 48 h after operation. Parent controlled intravenous analgesia with fentanyl(0.5 ug/kg for bolus and 0.5 ug/kg/hr for infusion, 10min of lockout) was used for adjuvant analgesia. Results: The mean visual analoque scale(0-10)was 3.4⫾2.9, 2.7⫾2.4, 1.1⫾1.0 on operation day, postoperative 1, 2 day, respectively. Both parents and surgeon showed satisfaction(5 scale; 1, no satisfaction; 5, high satisfaction) for this method(4(3-5), 4(2-5) in prents, surgeon, respectively). Postoperative nausea or vomiting were observed in 2 patients. Motor block was not observed. Conclusions: Our preliminary observations indicate that continuous fascia iliaca compartment block on one lower limb and sinlge fascia iliaca compartment block on another lower limb provides satisfactory postoperative pain relief following bilateral femoral osteotomy in pediatric patients.
249. Comparison of caudal epidural anesthesia with lidocaine-distilled water and lidocaine-mgSO4 mixture in cattle S.N. Dehghani, Z. Shafiei, A.S. Bigham [email protected] Department of Surgery and Radiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran Background: The most frequently used epidural anesthetic is lidocaine; mepivacaine, bupivacaine, and procaine are also used (Day and Skarda 1991). With the exception of bupivacaine, this group of agents provides analgesia of relatively short duration and may necessitate re-administration of the agent to allow completion of the procedure. Objective: To directly compare the time of onset and duration of analgesia produced by a Lidocaine-MgSO4 combination with that produced by Lidocaine-Distilled water administration in the caudal epidural space of dairy cattle. Animal: Five adult (4.6 ⫾ 0.5 years of age) dairy cows (480.0⫾71 kg). Methods: Caudal epidural anesthesia was produced in all cows with 2% lidocaine (0.22 mg/kg) with 1 ml distilled water and two weeks later repeated by lidocaine (0.22 mg/kg) with 1 ml of 10% MgSO4. Time to onset, duration and cranial spread of analgesia were recorded. Heart rate, Respiratory rate and body temperature were recorded. Results: Significant difference (p⬍0.05) was noted for time (mean ⫾ SEM) of onset of analgesia between Lidocaine-Distilled water (2.04 ⫾ 0.14 min) and Lidocaine-MgSO4 (4.70 ⫾ 0.20 min) that onset of analgesia following Lidocaine-MgSO4 was longer than Lidocaine-Distilled water. Lidocaine-MgSO4 produced analgesia of significantly longer duration (185.0 ⫾ 5.13 min) than that of Lidocaine - Distilled water (49.2 ⫾ 4.53 min). There were no significant differences in HR, RR, and body temperature between Lidocaine-Distilled water and Lidocaine-MgSO4. Conclusion: The combination of Lidocaine-MgSO4 produces analgesia longer than Lidocaine-Distilled water.
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Peripheral Nerve Block
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252. Postoperative analgesic effect of continuous fascia iliaca compartment block after femoral osteotomy in pediatrics with cerebral palsy A.Y. Oh, M.J. Yun, H.S. Kim, Y.S. Oh [email protected] Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Sungnam, Kyounggi, South Korea Background: To report a preliminary analysis of prospectively recorded data in 6 children with cerebral palsy in whom continuous fascia iliaca compartment block and single fascia iliaca compartment block on each lower limb were used for postoperative pain control following bilateral femur derotational osteotomy. Methods: Under general anesthesia, perineural catheters for continuous fascia iliaca compartment block were inserted on one lower limb and single fascia iliaca compartment block(0.25% bupivacaine 1 mg/kg) was done on another lower limb. Continuous fascia iliaca compartment block was done with a same bolus dose as the single block and a continuous infusion of 0.125% bupivacaine(0.2ml/kg/ hr) for 48 h after operation. Parent controlled intravenous analgesia with fentanyl(0.5 ug/kg for bolus and 0.5 ug/kg/hr for infusion, 10min of lockout) was used for adjuvant analgesia. Results: The mean visual analoque scale(0-10)was 3.4⫾2.9, 2.7⫾2.4, 1.1⫾1.0 on operation day, postoperative 1, 2 day, respectively. Both parents and surgeon showed satisfaction(5 scale; 1, no satisfaction; 5, high satisfaction) for this method(4(3-5), 4(2-5) in prents, surgeon, respectively). Postoperative nausea or vomiting were observed in 2 patients. Motor block was not observed. Conclusions: Our preliminary observations indicate that continuous fascia iliaca compartment block on one lower limb and sinlge fascia iliaca compartment block on another lower limb provides satisfactory postoperative pain relief following bilateral femoral osteotomy in pediatric patients.