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2801 Simulation study on the effects of two synaptic inputs on neural responses
S297
28. System
Theory
2801
SIMULATION STUDY ON THE EFFECTS OF TWO SYNAPTIC INPUTS ON NEURAL RESPONSES Computer Room, National Institute for Physiological Sciences, Okazaki 444, Japan’, Lab. of Neural Control, National Institute for Physiological Sciences, Okazaki 444, Japan” Hiroyuki ISHIIl , Hidehiko KOMATSU2 To obtain basic knowledge about the effects of synchronous synaptic inputs on neural responses, the interaction between two synaptic inputs was simulated. We used the model based on the cable theory for the passive dendrite and the compartmental model based on the ionic current mechanism for the active dendrite. We found that the way synaptic inputs interact is strongly dependent on the membrane properties of the dendrite, ether active or passive, as well as on the distance between two synapses or on the distance between synaptic input and soma.
2802
Statistical Study of Joint-PSTH
Dept. of Info. and Commun.
for Analysis of Dynamical Neuronal Code
Sci., Kyoto Sangyo University
Hiroyuki Ito, Satoshi Tsuji Aertsen introduced a method Joint-PSTH to study the non-stationary temporal relationship between the activities in the spike trains of two neurons. We examined its characteristics through the analysis of spike data created by a probabilistic model. We defined “effective connectivity” as a parameter of the model. The normalization factor was derived analytically for the data of different firing rates. We found the difficulty in the detection of negative correlation in spike trains of low firing and the problem in the definition of effective connectivity when both firing rate and correlation show non-stationary modulation.
28. System
Theory
2801
SIMULATION STUDY ON THE EFFECTS OF TWO SYNAPTIC INPUTS ON NEURAL RESPONSES Computer Room, National Institute for Physiological Sciences, Okazaki 444, Japan’, Lab. of Neural Control, National Institute for Physiological Sciences, Okazaki 444, Japan” Hiroyuki ISHIIl , Hidehiko KOMATSU2 To obtain basic knowledge about the effects of synchronous synaptic inputs on neural responses, the interaction between two synaptic inputs was simulated. We used the model based on the cable theory for the passive dendrite and the compartmental model based on the ionic current mechanism for the active dendrite. We found that the way synaptic inputs interact is strongly dependent on the membrane properties of the dendrite, ether active or passive, as well as on the distance between two synapses or on the distance between synaptic input and soma.
2802
Statistical Study of Joint-PSTH
Dept. of Info. and Commun.
for Analysis of Dynamical Neuronal Code
Sci., Kyoto Sangyo University
Hiroyuki Ito, Satoshi Tsuji Aertsen introduced a method Joint-PSTH to study the non-stationary temporal relationship between the activities in the spike trains of two neurons. We examined its characteristics through the analysis of spike data created by a probabilistic model. We defined “effective connectivity” as a parameter of the model. The normalization factor was derived analytically for the data of different firing rates. We found the difficulty in the detection of negative correlation in spike trains of low firing and the problem in the definition of effective connectivity when both firing rate and correlation show non-stationary modulation.