- Email: [email protected]
3100
Abstracts the morphology operation is applied, the tumor area is decided and it proposes the technique for displaying three dimensions.
P207
3D and extended ultrasonography is one of the latest developments in medical tomography. However, it is quite expensive, complex and slow. The method leads us to other diagnostic strategies and scanning techniques comparing conventional extended 2D ultrasound. 3D and extended ultrasonographic analysis provides more understandable information on the structures of interest, better anatomy presentation and more accurate measurements. Breast anatomy and masses can be characterized by a 2D extended ultrasound and mammography using the main categories: shape of the lesion, margin characteristics, depth and internal echogenicity. If the interface between a mass and its surrounding tissue is a key issue when attempts are made to define precisely the nature of the breast nodules, with 3D and extended images a major progress is anticipated. Because it’s noninvasive, this method will be used to diagnose along with a close cooperation of clinical experts around the world to further develop useful solutions.
Objectives: Real-time elastography, a new, noninvasive method for the diagnosis of breast cancer, was carried out in 108 candidate patients with histologically proven focal breast lesions. The goal of the study was to evaluate whether real-time elastography improves the differentiation and characterization of benign and malignant breast lesions. Methods: The study included 108 potential breast tumor patients with histologically confirmed focal lesions (59 benign, 49 malignant). Evaluation was performed using the 3D finite element method. The information is color-coded and superimposed on the B-mode ultrasound (US) scan. A second examiner was employed, in order to improve the objectivity of the method. The results were compared with histology and previous US findings. Sensitivities and specificities were calculated. Results: B-mode US had a sensitivity of 91.8% and a specificity of 78% compared with sensitivities of 77.6% and 79.6% and specificities of 91.5% and 84.7% for the two readers evaluating elastography. Agreement between B-mode US and elastography was good with McNemar’s test yielding a weighted of 0.67. Conclusions: Our initial clinical results suggest that real-time elastography is a promising new approach for the diagnosis of breast cancer. Elastography provides additional information for differentiating malignant BIRADS IV lesions.
3100
3103
Three-dimensional ultrasound of solid breast tumors: Pictorial presentation of BIRADS categories 3 and 4 cases and the preliminary experience in clinical application Chang T-H, Hsu G-C, Hsu H-H, Lin W-C, Chen C-Y, Yu J-C, Department of Radiology, Tri-Service General Hospital, Taiwan; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, Taiwan
Breast tumors—initial experience with sonoelastography Grunwald S, Ohlinger R, Schulz K, Schwesinger G, Heyer H, Frese H, Bobermien K, Institute of Gynecology and Obstetrics, Germany; Institute of Pathology, Germany
3099 Breast 3D and extended images Himmelstine LG, SONOMED/CIDEUS, Mexico
The purposes of this essay are to illustrate the imaging features of these tumors to correlate with pathological results. 3D imaging provides new information and allows a better interpretation of the 2D images. Moreover, 3D imaging could demonstrate better surface features and internal architecture of a tumor than 2D images, especially demonstrate infiltrative zone in malignant cases. We believe that 3D ultrasound is a promising tool that may enhance the diagnostic procedure between BIRADS categories 3 and 4 in clinical application. 3101 The evaluation of elastography application in differentiating Yi W, Fudan University Affiliated Huashan Hospital, China Objectives: To evaluate the elastography application in differentiating benign and malignant breast tumors. Methods: Collected 175 patients represented 184cases of breast tumors, using elastography to differentiate benign tumors from malignant tumors, and compared with post-operative pathological results. Results: Accuracy of elastography in differentiation breast tumors was 78.8% (145/184), while the sensitivity was 76.1% (51/67), the specificity was 80.3% (94/117). Conclusions: Elastography is a new valuable ultrasonography method in differentiating benign and malignant breast tumors. It is important that Elastography can efficiently decrease false-negative, notwithstanding maybe increase some case of false-positive.
Objectives: Breast lesions can be associated with altered tissue elasticity. The Sonorlastography module of the HITACHI EUB 8500Tissue permits real-time documentation of elasticity. Methods: Patients with histologically proven (core biopsy) breast lesions were examined. Sonoelastography results obtained with the HITACHI 8500 EUB were retrospectively analyzed by comparing them with B-mode imaging data, size information and the respective histological assessment after diagnostic excision. Results: A total of 22 patients underwent sonographic evaluation. In 16 of these women, benign lesions were known; there were three carcinomas and three cases of DCIS. A total of 26 benign lesions were visualized. Comparison of B-mode with sonoelastography images revealed that B-mode overestimated lesion size slightly, albeit not statistically significantly. Neither sonoelastography nor B-mode images appeared superior when compared to histologic size data. There was a marked variation in interobserver variability. Prediction of the benign versus malignant character of lesions using the elastography score did not demonstrate statistical significance. Conclusions: This initial evaluation did not reveal unequivocal advantages of sonoelastography, although the analysis is hampered by the small patient cohort and the examiners’ limited experience (learning curve). Breast sonoelastography does possess diagnostic potential, however. Larger prospective studies can further evaluate if this modality will become established in the diagnostic armamentarium. 3104
3102
Evaluation of local inverse problem analysis by transient shear wave generation for real-time quantitative elastography Yagi S, Sanuga A, Meisei University, Japan
An advanced method of ultrasound—real-time elastography: First results in 108 patients with breast lesions Kummel S, Fritzsche F, LichteneggerW, Fischer T, Thomas A, University Berlin, Charite, Germany
Objectives: In order to realize real-time quantitative elastography the tissue local inverse problem was numerically evaluated utilizing transient generation and traveling of low frequency local shear wave caused by spatio-temporal stress excitation normal to the tissue surface.
P207
3D and extended ultrasonography is one of the latest developments in medical tomography. However, it is quite expensive, complex and slow. The method leads us to other diagnostic strategies and scanning techniques comparing conventional extended 2D ultrasound. 3D and extended ultrasonographic analysis provides more understandable information on the structures of interest, better anatomy presentation and more accurate measurements. Breast anatomy and masses can be characterized by a 2D extended ultrasound and mammography using the main categories: shape of the lesion, margin characteristics, depth and internal echogenicity. If the interface between a mass and its surrounding tissue is a key issue when attempts are made to define precisely the nature of the breast nodules, with 3D and extended images a major progress is anticipated. Because it’s noninvasive, this method will be used to diagnose along with a close cooperation of clinical experts around the world to further develop useful solutions.
Objectives: Real-time elastography, a new, noninvasive method for the diagnosis of breast cancer, was carried out in 108 candidate patients with histologically proven focal breast lesions. The goal of the study was to evaluate whether real-time elastography improves the differentiation and characterization of benign and malignant breast lesions. Methods: The study included 108 potential breast tumor patients with histologically confirmed focal lesions (59 benign, 49 malignant). Evaluation was performed using the 3D finite element method. The information is color-coded and superimposed on the B-mode ultrasound (US) scan. A second examiner was employed, in order to improve the objectivity of the method. The results were compared with histology and previous US findings. Sensitivities and specificities were calculated. Results: B-mode US had a sensitivity of 91.8% and a specificity of 78% compared with sensitivities of 77.6% and 79.6% and specificities of 91.5% and 84.7% for the two readers evaluating elastography. Agreement between B-mode US and elastography was good with McNemar’s test yielding a weighted of 0.67. Conclusions: Our initial clinical results suggest that real-time elastography is a promising new approach for the diagnosis of breast cancer. Elastography provides additional information for differentiating malignant BIRADS IV lesions.
3100
3103
Three-dimensional ultrasound of solid breast tumors: Pictorial presentation of BIRADS categories 3 and 4 cases and the preliminary experience in clinical application Chang T-H, Hsu G-C, Hsu H-H, Lin W-C, Chen C-Y, Yu J-C, Department of Radiology, Tri-Service General Hospital, Taiwan; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, Taiwan
Breast tumors—initial experience with sonoelastography Grunwald S, Ohlinger R, Schulz K, Schwesinger G, Heyer H, Frese H, Bobermien K, Institute of Gynecology and Obstetrics, Germany; Institute of Pathology, Germany
3099 Breast 3D and extended images Himmelstine LG, SONOMED/CIDEUS, Mexico
The purposes of this essay are to illustrate the imaging features of these tumors to correlate with pathological results. 3D imaging provides new information and allows a better interpretation of the 2D images. Moreover, 3D imaging could demonstrate better surface features and internal architecture of a tumor than 2D images, especially demonstrate infiltrative zone in malignant cases. We believe that 3D ultrasound is a promising tool that may enhance the diagnostic procedure between BIRADS categories 3 and 4 in clinical application. 3101 The evaluation of elastography application in differentiating Yi W, Fudan University Affiliated Huashan Hospital, China Objectives: To evaluate the elastography application in differentiating benign and malignant breast tumors. Methods: Collected 175 patients represented 184cases of breast tumors, using elastography to differentiate benign tumors from malignant tumors, and compared with post-operative pathological results. Results: Accuracy of elastography in differentiation breast tumors was 78.8% (145/184), while the sensitivity was 76.1% (51/67), the specificity was 80.3% (94/117). Conclusions: Elastography is a new valuable ultrasonography method in differentiating benign and malignant breast tumors. It is important that Elastography can efficiently decrease false-negative, notwithstanding maybe increase some case of false-positive.
Objectives: Breast lesions can be associated with altered tissue elasticity. The Sonorlastography module of the HITACHI EUB 8500Tissue permits real-time documentation of elasticity. Methods: Patients with histologically proven (core biopsy) breast lesions were examined. Sonoelastography results obtained with the HITACHI 8500 EUB were retrospectively analyzed by comparing them with B-mode imaging data, size information and the respective histological assessment after diagnostic excision. Results: A total of 22 patients underwent sonographic evaluation. In 16 of these women, benign lesions were known; there were three carcinomas and three cases of DCIS. A total of 26 benign lesions were visualized. Comparison of B-mode with sonoelastography images revealed that B-mode overestimated lesion size slightly, albeit not statistically significantly. Neither sonoelastography nor B-mode images appeared superior when compared to histologic size data. There was a marked variation in interobserver variability. Prediction of the benign versus malignant character of lesions using the elastography score did not demonstrate statistical significance. Conclusions: This initial evaluation did not reveal unequivocal advantages of sonoelastography, although the analysis is hampered by the small patient cohort and the examiners’ limited experience (learning curve). Breast sonoelastography does possess diagnostic potential, however. Larger prospective studies can further evaluate if this modality will become established in the diagnostic armamentarium. 3104
3102
Evaluation of local inverse problem analysis by transient shear wave generation for real-time quantitative elastography Yagi S, Sanuga A, Meisei University, Japan
An advanced method of ultrasound—real-time elastography: First results in 108 patients with breast lesions Kummel S, Fritzsche F, LichteneggerW, Fischer T, Thomas A, University Berlin, Charite, Germany
Objectives: In order to realize real-time quantitative elastography the tissue local inverse problem was numerically evaluated utilizing transient generation and traveling of low frequency local shear wave caused by spatio-temporal stress excitation normal to the tissue surface.