- Email: [email protected]
365-nm Narrowband Wood's Lamp for Vitiligo and Hypopigmentation Disorders
Journal Pre-proof 365-nm Narrowband Wood's Lamp for Vitiligo and Hypopigmentation Disorders Jung Min Bae, MD, PhD, Ro Woo Lee, MD PII:
S0190-9622(19)32670-2
DOI:
https://doi.org/10.1016/j.jaad.2019.08.064
Reference:
YMJD 13786
To appear in:
Journal of the American Academy of Dermatology
Received Date: 23 June 2019 Revised Date:
19 August 2019
Accepted Date: 25 August 2019
Please cite this article as: Bae JM, Lee RW, 365-nm Narrowband Wood's Lamp for Vitiligo and Hypopigmentation Disorders, Journal of the American Academy of Dermatology (2019), doi: https:// doi.org/10.1016/j.jaad.2019.08.064. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2019 Published by Elsevier on behalf of the American Academy of Dermatology, Inc.
Technology Pearl 365-nm Narrowband Wood's Lamp for Vitiligo and Hypopigmentation Disorders
Jung Min Bae, MD, PhD, Ro Woo Lee, MD
Department of Dermatology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
Corresponding author: Jung Min Bae, MD, PhD Department of Dermatology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea 93, Jungbu-daero, Paldal-gu, Suwon 16247, Korea Tel: +82-31- 249-8970 Fax: +82-31- 253-9950 E-mail: [email protected]
Funding sources: This study was funded by the Ministry of Science, ICT & Future Planning (grant number: NRF- 2017R1E1A1A01076780). IRB approval status: Reviewed and approved by the Institutional Review Board of St. Vincent’s Hospital (VC18ZESI0267). Conflict of Interest Disclosure: None Declared.
Manuscript word count: 245 Figures: 2 Keywords: dermoscopy, melanin, melanocyte, photography, ultraviolet, vitiligo
TECHNOLOGIC CHALLENGE Wood’s lamps have been widely used to evaluate various pigmentary skin disorders, including vitiligo and melasma.1 A Wood’s lamp has broadband light sources that emit light at wavelengths between 320 and 400 nm, with a peak at 365 nm. Under a Wood’s lamp, objects typically look blue; not because of ultraviolet light but because of visible rays composed of purple to blue light.
SOLUTION A narrowband Wood’s lamp using 365-nm LEDs (IDS-3100; Illuco, Gunpo, Korea) can provide more accurate information in vitiligo and other hypopigmentation disorders. It makes vitiligo lesions more visible without the bluish tone typically seen with a traditional broadband Wood’s lamp (Fig. 1). The retina has two types of light receptors: cone cells and rod cells.2 While cone cells are active at higher light levels to enable color vision and high spatial acuity, rod cells are responsible for vision at low light levels. At the short wavelength end of visible light, blue cone cells react to recognize blue color, but with ultraviolet light beyond the action spectrum of cone cells, only rod cells react. Moreover, melanin absorbs 365-nm wavelength light more strongly, so rod cells in the retina can recognize the presence of melanin under 365-nm light, enhancing the contrast between the hypopigmented lesion and surrounding normal skin. Therefore, a 365-nm narrowband Wood’s lamp could be useful for examining various hypopigmentation disorders, including the treatment response of vitiligo, pityriasis alba, and nevus depigmentosus, in patients with light skin (Fig. 2).
REFERENCES 1.
Klatte JL, van der Beek N, Kemperman PM. 100 years of Wood’s lamp revised. J Eur Acad Dermatol Venereol. 2015;29:842–847.
2.
Chen J, Sampath AP. 16. Structure and Function of Rod and Cone Photoreceptors. In: Schachat AP, Sadda SR, Hinton DR, Wilkinson CP, Wiedemann P, eds. Ryan's Retina. 6th ed. Amsterdam, Netherlands: Elsevier; 2017:387-407.
Figure legends Figure 1. A 365-nm narrowband Wood’s lamp for assessing a vitiligo lesion. (A) The common appearance of vitiligo under room light. (B) Vitiligo is highly visible with great contrast under a 365-nm narrowband Wood’s lamp. (C) A traditional Wood’s lamp unintentionally makes objectives look bluish.
Figure 2. Use of a 365-nm narrowband Wood’s lamp for various hypopigmentation disorders. (A & D) Treatment response of vitiligo, (B & E) pityriasis alba, and (C & F) nevus depigmentosus (A, B, and C: under room light, D, E, and F: under a 365-nm narrowband Wood’s lamp).
S0190-9622(19)32670-2
DOI:
https://doi.org/10.1016/j.jaad.2019.08.064
Reference:
YMJD 13786
To appear in:
Journal of the American Academy of Dermatology
Received Date: 23 June 2019 Revised Date:
19 August 2019
Accepted Date: 25 August 2019
Please cite this article as: Bae JM, Lee RW, 365-nm Narrowband Wood's Lamp for Vitiligo and Hypopigmentation Disorders, Journal of the American Academy of Dermatology (2019), doi: https:// doi.org/10.1016/j.jaad.2019.08.064. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2019 Published by Elsevier on behalf of the American Academy of Dermatology, Inc.
Technology Pearl 365-nm Narrowband Wood's Lamp for Vitiligo and Hypopigmentation Disorders
Jung Min Bae, MD, PhD, Ro Woo Lee, MD
Department of Dermatology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
Corresponding author: Jung Min Bae, MD, PhD Department of Dermatology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea 93, Jungbu-daero, Paldal-gu, Suwon 16247, Korea Tel: +82-31- 249-8970 Fax: +82-31- 253-9950 E-mail: [email protected]
Funding sources: This study was funded by the Ministry of Science, ICT & Future Planning (grant number: NRF- 2017R1E1A1A01076780). IRB approval status: Reviewed and approved by the Institutional Review Board of St. Vincent’s Hospital (VC18ZESI0267). Conflict of Interest Disclosure: None Declared.
Manuscript word count: 245 Figures: 2 Keywords: dermoscopy, melanin, melanocyte, photography, ultraviolet, vitiligo
TECHNOLOGIC CHALLENGE Wood’s lamps have been widely used to evaluate various pigmentary skin disorders, including vitiligo and melasma.1 A Wood’s lamp has broadband light sources that emit light at wavelengths between 320 and 400 nm, with a peak at 365 nm. Under a Wood’s lamp, objects typically look blue; not because of ultraviolet light but because of visible rays composed of purple to blue light.
SOLUTION A narrowband Wood’s lamp using 365-nm LEDs (IDS-3100; Illuco, Gunpo, Korea) can provide more accurate information in vitiligo and other hypopigmentation disorders. It makes vitiligo lesions more visible without the bluish tone typically seen with a traditional broadband Wood’s lamp (Fig. 1). The retina has two types of light receptors: cone cells and rod cells.2 While cone cells are active at higher light levels to enable color vision and high spatial acuity, rod cells are responsible for vision at low light levels. At the short wavelength end of visible light, blue cone cells react to recognize blue color, but with ultraviolet light beyond the action spectrum of cone cells, only rod cells react. Moreover, melanin absorbs 365-nm wavelength light more strongly, so rod cells in the retina can recognize the presence of melanin under 365-nm light, enhancing the contrast between the hypopigmented lesion and surrounding normal skin. Therefore, a 365-nm narrowband Wood’s lamp could be useful for examining various hypopigmentation disorders, including the treatment response of vitiligo, pityriasis alba, and nevus depigmentosus, in patients with light skin (Fig. 2).
REFERENCES 1.
Klatte JL, van der Beek N, Kemperman PM. 100 years of Wood’s lamp revised. J Eur Acad Dermatol Venereol. 2015;29:842–847.
2.
Chen J, Sampath AP. 16. Structure and Function of Rod and Cone Photoreceptors. In: Schachat AP, Sadda SR, Hinton DR, Wilkinson CP, Wiedemann P, eds. Ryan's Retina. 6th ed. Amsterdam, Netherlands: Elsevier; 2017:387-407.
Figure legends Figure 1. A 365-nm narrowband Wood’s lamp for assessing a vitiligo lesion. (A) The common appearance of vitiligo under room light. (B) Vitiligo is highly visible with great contrast under a 365-nm narrowband Wood’s lamp. (C) A traditional Wood’s lamp unintentionally makes objectives look bluish.
Figure 2. Use of a 365-nm narrowband Wood’s lamp for various hypopigmentation disorders. (A & D) Treatment response of vitiligo, (B & E) pityriasis alba, and (C & F) nevus depigmentosus (A, B, and C: under room light, D, E, and F: under a 365-nm narrowband Wood’s lamp).