3D ECHOCARDIOGRAPHY ENHANCED AREA MEASUREMENTS OF THE LEFT VENTRICULAR OUTFLOW TRACT IMPROVES ASSESSMENT OF STROKE VOLUME: COMPARISON WITH 2D ECHO

3D ECHOCARDIOGRAPHY ENHANCED AREA MEASUREMENTS OF THE LEFT VENTRICULAR OUTFLOW TRACT IMPROVES ASSESSMENT OF STROKE VOLUME: COMPARISON WITH 2D ECHO

1653 JACC April 5, 2016 Volume 67, Issue 13 Non Invasive Imaging (Echocardiography, Nuclear, PET, MR and CT) 3D ECHOCARDIOGRAPHY ENHANCED AREA MEASUR...

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1653 JACC April 5, 2016 Volume 67, Issue 13

Non Invasive Imaging (Echocardiography, Nuclear, PET, MR and CT) 3D ECHOCARDIOGRAPHY ENHANCED AREA MEASUREMENTS OF THE LEFT VENTRICULAR OUTFLOW TRACT IMPROVES ASSESSMENT OF STROKE VOLUME: COMPARISON WITH 2D ECHO Poster Contributions Poster Area, South Hall A1 Saturday, April 02, 2016, 3:45 p.m.-4:30 p.m. Session Title: New Technologies in Echocardiography Abstract Category: 29. Non Invasive Imaging: Echo Presentation Number: 1149-233 Authors: David J. Sahn, Priyanka Mathur, Kacie Amacher, Evan Tracy, Muhammad Ashraf, Oregon Health & Science University, Portland, OR, USA

Background: 2D echo derived linear measurement and Doppler derived velocity information from the left ventricular outflow tract (LVOT) is frequently used to compute stroke volume (SV), which is subject to errors due to geometrical assumptions. We tested feasibility of using 3D echo derived area measurements for this computation. Methods: Ten freshly harvested pig hearts were studied. A latex balloon was secured into the left ventricle of each heart and pulsatile flow was generated using calibrated pump at different SVs (30-70 mL). 2DE and RT3DE images were acquired using a parasternal long axis view while the Doppler images were collected using an apical view; both used GE Vivid 9E ultrasound system. GE EchoPAC software was used to analyze 2DE, RT3DE and Doppler images to determine LVOT area and the velocity time interval (VTI). Results: The data indicates that compared to the reference SVs, RT3DE (R² = 0.930; p<0.001; %error = 8.22%) better evaluated the SV compared to 2DE (R² = 0.895; p<0.001; %error = 17.5%). The linear regression and Bland-Altman analyses indicate moderate variability between 2DE and RT3DE (p<0.001; R²=0.889). Conclusions: Real-time 3-dimensional echocardiography enhanced area measurements are superior to linear dimensions to compute stroke volume with Doppler derived VTI.