- Email: [email protected]
419 COMPARISON OF CONTRAST-ENHANCED ULTRASOUND (CE-US) AND COMPUTED TOMOGRAPHY (CT) IN THE EVALUATION OF COMPLEX CYSTIC RENAL MASSES
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419
COMPARISON OF CONTRAST-ENHANCED ULTRASOUND (CE-US) AND COMPUTED TOMOGRAPHY (CT) IN THE EVALUATION OF COMPLEX CYSTIC RENAL MASSES
*DUFLD5RMR'%DOOHVWHURV(0DOHW$3UHUD$$EDG&9LFHQWH( 0DUWRV5*RQ]DOH]6DOD-/0DUW¯Q-%DUULR00X³R]-3XLJ- +DQQDRXL1'DUQHOO$3UDWV- 1 Corporacio Parc Tauli, Dept. of Urology, Sabadell, Spain, 2Corporacio Parc Tauli, Dept. of Radiology, Sabadell, Spain Introduction & Objectives: 5HQDOF\VWVDUHFRPPRQLQFLGHQWDOᚏQGLQJVGXULQJWKH FOLQLFDOGLDJQRVWLFZRUNXSRISDWLHQWV,QUHQDOF\VWVWKHOLNHOLKRRGRIPDOLJQDQF\LV DVVHVVHGXVLQJWKH%RVQLDNFODVVLᚏFDWLRQEDVHGRQLQWUDYHQRXVFRQWUDVWHQKDQFHG &7,QWKLVVWXG\ZHUHSRUWHGWKHᚏQGLQJVRIFRPSOH[UHQDOF\VWVVWXGLHGZLWK&( 86LQFRPSDULVRQZLWK&7 Material & Methods: 7KLV SURVSHFWLYH VWXG\ LQFOXGHG F\VWLF UHQDO PDVVHV LQ FRQVHFXWLYH SDWLHQWV 7KH &7 DQG &(86 LPDJHV ZHUH VWXGLHG IRU VHSWD QXPEHUV ZDOO DQGRU WKLFNQHVV HQKDQFHPHQW GHJUHH DQG IRU WKH SUHVHQFH RI D VROLG FRPSRQHQW E\ FRQVHQVXV EHWZHHQ WZR UDGLRORJLVWV XVLQJ WKH %RVQLDN FODVVLᚏFDWLRQ &(86 HPSOR\HG D ORZ0, WHFKQLTXH XVLQJ D PO RI VHFRQG JHQHUDWLRQFRQWUDVWDJHQW 6RQR9XH ([DPLQDWLRQRIUHQDOF\VWVZDVHYDOXDWHG LQUHQDOWLPHXQWLOPLQXWHV$GLJLWDOYLGHRFOLSRIWKHHQWLUHH[DPLQDWLRQZDV VWRUHGIRUSRVWHULRUHYDOXDWLRQ:HRᚎHUHGWKHSUDFWLFHRIVXUJHU\IRUSDWLHQWVZLWK %RVQLDN,,,DQG,9F\VWVGHWHFWHGZLWK&(86RU&77KRVHSDWLHQWVZKRUHIXVHG VXUJHU\DQGVXEMHFWVZLWK%RVQLDN,,)F\VWVZHUHIROORZHGSHULRGLFDOO\E\&7DQG &(86:HFRPSDUHWKHKLVWRORJLFDOVWXGLHVRIVXUJLFDOVSHFLPHQVZLWKWKHᚏQGLQJV DW&(86DQG&77KH&RKHQVWDWLVWLFZDVXVHGWRDQDO\]HDJUHHPHQWEHWZHHQ WKHGLDJQRVWLFSURFHGXUHV Results: %RVQLDN&DWHJRU\ /HVLRQVVHHQRQ&(86ZHUHFODVVLᚏHGDV%RVQLDN FDWHJRU\ , Q ,, Q ,,I Q ,,, Q RU ,9 Q /HVLRQV RQ &7 ZHUH FODVVLᚏHG DV %RVQLDN FDWHJRU\ , Q ,, Q ,,I Q ,,, Q RU ,9 Q &RQFRUGDQFH EHWZHHQ &(86 DQG FRQWUDVWHQKDFHG &7 ZDV KLJK N ,& :HREVHUYHGXQGHUVWDWLQJE\&7LQ%RVQLDN,,,F\VWVDQGLQRQH %RVQLDN,9F\VW7ZRRIWKHQHRSODVPVXQJUDGHGZHUHVXUJLFDOO\UHPRYHGDQG KLVWRORJLFVWXG\VKRZHGPDOLJQDQF\&7KDVGHWHFWHGFDOFLᚏFDWLRQVRIWKHF\VWVLQ ᚏYHFDVHVPRUHWKDQWKH&(86%XW&(86DSSUHFLDWHVEHWWHULQWHUQDOOHVLRQVRI WKHF\VWVH[FHSWIRUWKRVHZLWKDᚏQHO\FDOFLᚏHGZDOO6L[RIWKHVHYHQSDWLHQWVZLWK %RVQLDN,9F\VWVDQGRQO\RQHRIWKHSDWLHQWVFODVVLᚏHGDV%RVQLDN,,,F\VWVLQ DQ\RIWKHUDGLRORJLFVWXGLHVXQGHUJRQHVXUJHU\7KHKLVWRORJLFᚏQGLQJVRIWKHDOO UHVHFWHGPDVVHVVKRZHGUHQDOFHOOFDUFLQRPD:HGLGQRWREVHUYHGWXPRUJURZWK LQWKHUHPDLQLQJVHYHQSDWLHQWVZKRZDVQRWRSHUDWHGZLWKDPHDQIROORZXSRI PRQWKV Conclusions: &(86LV D WHFKQLTXH HTXLYDOHQW WRWKH &7 WRDVVHVV UHQDO F\VWV FRPSOLFDWHG IRU WKH %RVQLDN FODVVLᚏFDWLRQ ,Q RXU H[SHULHQFH &(8V ZDV IRXQG WR EH EHWWHU WKDQ 7& LQ WKH GLDJQRVLV RI PDOLJQDQF\ LQ %RVQLDN ,,I DQG ,,, UHQDO F\VWV7KHMRLQWXVHRI&7DQG&(86SURYLGHXVHIXOLQIRUPDWLRQIRUGHFLGLQJWKH
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420
THE VALUE OF THE BOSNIAK CLASSIFICATION FOR PATHOLOGY OUTCOME IN LAPAROSCOPIC PARTIAL NEFRECTOMY
)UDQNHQ9&'HNNHU+00XOGHUV3)$/DQJHQKXLMVHQ-) 1 Radboud University Nijmegen Medical Centre, Dept. of Urology, Nijmegen, The Netherlands, 2Radboud University Nijmegen Medical Centre, Dept. of Radiology, Nijmegen, The Netherlands Introduction & Objectives: &RPSOLFDWHG F\VWV RI WKH NLGQH\ FDQ EH FODVVLᚏHG DFFRUGLQJWRWKH%RVQLDNFODVVLᚏFDWLRQ$FFRUGLQJWRWKHᚏQGLQJVLQUHWURVSHFWLYH VWXGLHVWKHFKDQFHRIPDOLJQDQF\LQFUHDVHVZLWKDKLJKHU%RVQLDNVFRUH5HQDOFHOO FDQFHU 5&& LVIRXQGLQRI%RVQLDN,,)F\VWVRI%RVQLDN,,,F\VWVDQGXSWR RI%RVQLDN,9F\VWV7KHUHIRUHZLWKD%RVQLDN,,,VFRUHRUKLJKHUDUHVHFWLRQ RIWKHF\VWLVDGYLVHG,QWKLVVWXG\WKHSDWKRORJ\RXWFRPHVRISDUWLDOQHIUHFWRP\ VSHFLPHQVIRUFRPSOLFDWHGF\VWVDUHFRPSDUHGWRWKH%RVQLDNFODVVLᚏFDWLRQJLYHQ E\WKHUDGLRORJLVWRQSUHRSHUDWLYH&7VFDQ Material & Methods: 3DWLHQWVZKRXQGHUZHQWDODSDURVFRSLFSDUWLDOQHIUHFWRP\ EHWZHHQ-DQXDU\DQG-XO\ IRUDFRPSOLFDWHGF\VWZHUHLQFOXGHGLQWKLV VWXG\ 7KH %RVQLDN FODVVLᚏFDWLRQ ZDV VFRUHG UHWURVSHFWLYHO\ E\ RQH UDGLRORJLVW ZKRZDVEOLQGHGIRUWKHSDWKRORJ\UHSRUWDQGIRUWKHSULPDU\FODVVLᚏFDWLRQRIWKH F\VWJLYHQE\RWKHUUDGLRORJLVWV7KHF\VWVZHUHVFRUHGDFFRUGLQJWRUDGLRORJLFDO FKDUDFWHULVWLFV RQ SUHRSHUDWLYH &7VFDQ ZLWK LQWUDYHQRXV FRQWUDVW QDPHO\ FDOFLᚏFDWLRQ DQG WKLFNQHVV RI F\VWLF ZDOO VHSWDWLRQ VL]H VROLG FRPSRQHQWV HQKDQFHPHQWDQG+RXQVᚏHOGXQLWV7KH%RVQLDNFODVVLᚏFDWLRQZDVFRPSDUHGWR WKHSDWKRORJ\RXWFRPH Results: ,QWRWDOSDWLHQWVXQGHUZHQWDSDUWLDOQHIUHFWRP\IRUFRPSOLFDWHGF\VWV RU VROLG WXPRXUV LQ WKH VWXG\ SHULRG ,Q WKLV JURXS SDWLHQWV ZHUH GLDJQRVHG ZLWKDFRPSOLFDWHGF\VWIRUZKLFKODSDURVFRSLFSDUWLDOQHIUHFWRP\ZDVSHUIRUPHG 3DWLHQWVZLWK9RQ+LSSHO/LQGDXGLVHDVHZHUHH[FOXGHG7KHPHGLDQGLDPHWHURI WKHF\VWVZDVFP UDQJHದFP 7KHPHGLDQDJHRISDWLHQWVZDV \HDUV \U $%RVQLDN,,)ZDVVFRUHGLQF\VWVRIZKLFKZHUHEHQLJQ DQG VKRZHG D SDSLOODU\ 5&& RQ SDWKRORJ\ $ %RVQLDN ,,, ZDV VFRUHG LQ FDVHVRIZKLFK Q ZDVDQ5&&$%RVQLDN,9ZDVVFRUHGLQF\VWV DQG RIWKHVHZHUH5&&2QHF\VWVZDVVKRZQWREHFKURQLFLQᚐDPPDWLRQ 7DEOH 7DEOH 1 %RVQLDN,,) Q %RVQLDN,,, Q %RVQLDN,9 Q
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421
IMMUNOPET IMAGING OF RENAL CELL CARCINOMA WITH 124I- AND 89ZR-LABELED ANTI-CAIX MONOCLONAL ANTIBODY CG250
6WLOOHEURHU$)UDQVVHQ*0%RHUPDQ2&2RVWHUZLMN(/DYHUPDQ3 2\HQ:-*0XOGHUV3)$ 1 Radboud University Nijmegen Medical Centre, Dept. of Urology, Nijmegen, The Netherlands, 2Radboud University Nijmegen Medical Centre, Dept. of Nuclear Medicine, Nijmegen, The Netherlands Introduction & Objectives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aterial & Methods: 1XGHPLFH SHUJURXS ZLWKGLᚎHUHQWVFRULSFF5&& [HQRJUDIWV 6.5& 18 ZHUH LY LQMHFWHG ZLWK 0%T =UF* 0%T ,F*RU0%T ))'*7RGHWHUPLQHVSHFLᚏFLW\RIF*XSWDNHLQ FF5&&RQHJURXSRIPLFHZDVLYLQMHFWHGZLWK0%T =U023& LUUHOHYDQW P$E 3(7 LPDJHV ZHUH DFTXLUHG XVLQJ D GHGLFDWHG VPDOO DQLPDO3(7 FDPHUD 6LHPHQV ,QYHRQ GLUHFWO\ DQG GD\V SL 0LFH ZHUH NLOOHG DIWHU WKH ODVW LPDJLQJVHVVLRQDQGWKHFRQFHQWUDWLRQRIWKHUDGLRODEHOHGP$ELQWKHGLVVHFWHG WLVVXHVZDVGHWHUPLQHG
Eur Urol Suppl 2010;9(2):153
419
COMPARISON OF CONTRAST-ENHANCED ULTRASOUND (CE-US) AND COMPUTED TOMOGRAPHY (CT) IN THE EVALUATION OF COMPLEX CYSTIC RENAL MASSES
*DUFLD5RMR'%DOOHVWHURV(0DOHW$3UHUD$$EDG&9LFHQWH( 0DUWRV5*RQ]DOH]6DOD-/0DUW¯Q-%DUULR00X³R]-3XLJ- +DQQDRXL1'DUQHOO$3UDWV- 1 Corporacio Parc Tauli, Dept. of Urology, Sabadell, Spain, 2Corporacio Parc Tauli, Dept. of Radiology, Sabadell, Spain Introduction & Objectives: 5HQDOF\VWVDUHFRPPRQLQFLGHQWDOᚏQGLQJVGXULQJWKH FOLQLFDOGLDJQRVWLFZRUNXSRISDWLHQWV,QUHQDOF\VWVWKHOLNHOLKRRGRIPDOLJQDQF\LV DVVHVVHGXVLQJWKH%RVQLDNFODVVLᚏFDWLRQEDVHGRQLQWUDYHQRXVFRQWUDVWHQKDQFHG &7,QWKLVVWXG\ZHUHSRUWHGWKHᚏQGLQJVRIFRPSOH[UHQDOF\VWVVWXGLHGZLWK&( 86LQFRPSDULVRQZLWK&7 Material & Methods: 7KLV SURVSHFWLYH VWXG\ LQFOXGHG F\VWLF UHQDO PDVVHV LQ FRQVHFXWLYH SDWLHQWV 7KH &7 DQG &(86 LPDJHV ZHUH VWXGLHG IRU VHSWD QXPEHUV ZDOO DQGRU WKLFNQHVV HQKDQFHPHQW GHJUHH DQG IRU WKH SUHVHQFH RI D VROLG FRPSRQHQW E\ FRQVHQVXV EHWZHHQ WZR UDGLRORJLVWV XVLQJ WKH %RVQLDN FODVVLᚏFDWLRQ &(86 HPSOR\HG D ORZ0, WHFKQLTXH XVLQJ D PO RI VHFRQG JHQHUDWLRQFRQWUDVWDJHQW 6RQR9XH ([DPLQDWLRQRIUHQDOF\VWVZDVHYDOXDWHG LQUHQDOWLPHXQWLOPLQXWHV$GLJLWDOYLGHRFOLSRIWKHHQWLUHH[DPLQDWLRQZDV VWRUHGIRUSRVWHULRUHYDOXDWLRQ:HRᚎHUHGWKHSUDFWLFHRIVXUJHU\IRUSDWLHQWVZLWK %RVQLDN,,,DQG,9F\VWVGHWHFWHGZLWK&(86RU&77KRVHSDWLHQWVZKRUHIXVHG VXUJHU\DQGVXEMHFWVZLWK%RVQLDN,,)F\VWVZHUHIROORZHGSHULRGLFDOO\E\&7DQG &(86:HFRPSDUHWKHKLVWRORJLFDOVWXGLHVRIVXUJLFDOVSHFLPHQVZLWKWKHᚏQGLQJV DW&(86DQG&77KH&RKHQVWDWLVWLFZDVXVHGWRDQDO\]HDJUHHPHQWEHWZHHQ WKHGLDJQRVWLFSURFHGXUHV Results: %RVQLDN&DWHJRU\ /HVLRQVVHHQRQ&(86ZHUHFODVVLᚏHGDV%RVQLDN FDWHJRU\ , Q ,, Q ,,I Q ,,, Q RU ,9 Q /HVLRQV RQ &7 ZHUH FODVVLᚏHG DV %RVQLDN FDWHJRU\ , Q ,, Q ,,I Q ,,, Q RU ,9 Q &RQFRUGDQFH EHWZHHQ &(86 DQG FRQWUDVWHQKDFHG &7 ZDV KLJK N ,& :HREVHUYHGXQGHUVWDWLQJE\&7LQ%RVQLDN,,,F\VWVDQGLQRQH %RVQLDN,9F\VW7ZRRIWKHQHRSODVPVXQJUDGHGZHUHVXUJLFDOO\UHPRYHGDQG KLVWRORJLFVWXG\VKRZHGPDOLJQDQF\&7KDVGHWHFWHGFDOFLᚏFDWLRQVRIWKHF\VWVLQ ᚏYHFDVHVPRUHWKDQWKH&(86%XW&(86DSSUHFLDWHVEHWWHULQWHUQDOOHVLRQVRI WKHF\VWVH[FHSWIRUWKRVHZLWKDᚏQHO\FDOFLᚏHGZDOO6L[RIWKHVHYHQSDWLHQWVZLWK %RVQLDN,9F\VWVDQGRQO\RQHRIWKHSDWLHQWVFODVVLᚏHGDV%RVQLDN,,,F\VWVLQ DQ\RIWKHUDGLRORJLFVWXGLHVXQGHUJRQHVXUJHU\7KHKLVWRORJLFᚏQGLQJVRIWKHDOO UHVHFWHGPDVVHVVKRZHGUHQDOFHOOFDUFLQRPD:HGLGQRWREVHUYHGWXPRUJURZWK LQWKHUHPDLQLQJVHYHQSDWLHQWVZKRZDVQRWRSHUDWHGZLWKDPHDQIROORZXSRI PRQWKV Conclusions: &(86LV D WHFKQLTXH HTXLYDOHQW WRWKH &7 WRDVVHVV UHQDO F\VWV FRPSOLFDWHG IRU WKH %RVQLDN FODVVLᚏFDWLRQ ,Q RXU H[SHULHQFH &(8V ZDV IRXQG WR EH EHWWHU WKDQ 7& LQ WKH GLDJQRVLV RI PDOLJQDQF\ LQ %RVQLDN ,,I DQG ,,, UHQDO F\VWV7KHMRLQWXVHRI&7DQG&(86SURYLGHXVHIXOLQIRUPDWLRQIRUGHFLGLQJWKH
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420
THE VALUE OF THE BOSNIAK CLASSIFICATION FOR PATHOLOGY OUTCOME IN LAPAROSCOPIC PARTIAL NEFRECTOMY
)UDQNHQ9&'HNNHU+00XOGHUV3)$/DQJHQKXLMVHQ-) 1 Radboud University Nijmegen Medical Centre, Dept. of Urology, Nijmegen, The Netherlands, 2Radboud University Nijmegen Medical Centre, Dept. of Radiology, Nijmegen, The Netherlands Introduction & Objectives: &RPSOLFDWHG F\VWV RI WKH NLGQH\ FDQ EH FODVVLᚏHG DFFRUGLQJWRWKH%RVQLDNFODVVLᚏFDWLRQ$FFRUGLQJWRWKHᚏQGLQJVLQUHWURVSHFWLYH VWXGLHVWKHFKDQFHRIPDOLJQDQF\LQFUHDVHVZLWKDKLJKHU%RVQLDNVFRUH5HQDOFHOO FDQFHU 5&& LVIRXQGLQRI%RVQLDN,,)F\VWVRI%RVQLDN,,,F\VWVDQGXSWR RI%RVQLDN,9F\VWV7KHUHIRUHZLWKD%RVQLDN,,,VFRUHRUKLJKHUDUHVHFWLRQ RIWKHF\VWLVDGYLVHG,QWKLVVWXG\WKHSDWKRORJ\RXWFRPHVRISDUWLDOQHIUHFWRP\ VSHFLPHQVIRUFRPSOLFDWHGF\VWVDUHFRPSDUHGWRWKH%RVQLDNFODVVLᚏFDWLRQJLYHQ E\WKHUDGLRORJLVWRQSUHRSHUDWLYH&7VFDQ Material & Methods: 3DWLHQWVZKRXQGHUZHQWDODSDURVFRSLFSDUWLDOQHIUHFWRP\ EHWZHHQ-DQXDU\DQG-XO\ IRUDFRPSOLFDWHGF\VWZHUHLQFOXGHGLQWKLV VWXG\ 7KH %RVQLDN FODVVLᚏFDWLRQ ZDV VFRUHG UHWURVSHFWLYHO\ E\ RQH UDGLRORJLVW ZKRZDVEOLQGHGIRUWKHSDWKRORJ\UHSRUWDQGIRUWKHSULPDU\FODVVLᚏFDWLRQRIWKH F\VWJLYHQE\RWKHUUDGLRORJLVWV7KHF\VWVZHUHVFRUHGDFFRUGLQJWRUDGLRORJLFDO FKDUDFWHULVWLFV RQ SUHRSHUDWLYH &7VFDQ ZLWK LQWUDYHQRXV FRQWUDVW QDPHO\ FDOFLᚏFDWLRQ DQG WKLFNQHVV RI F\VWLF ZDOO VHSWDWLRQ VL]H VROLG FRPSRQHQWV HQKDQFHPHQWDQG+RXQVᚏHOGXQLWV7KH%RVQLDNFODVVLᚏFDWLRQZDVFRPSDUHGWR WKHSDWKRORJ\RXWFRPH Results: ,QWRWDOSDWLHQWVXQGHUZHQWDSDUWLDOQHIUHFWRP\IRUFRPSOLFDWHGF\VWV RU VROLG WXPRXUV LQ WKH VWXG\ SHULRG ,Q WKLV JURXS SDWLHQWV ZHUH GLDJQRVHG ZLWKDFRPSOLFDWHGF\VWIRUZKLFKODSDURVFRSLFSDUWLDOQHIUHFWRP\ZDVSHUIRUPHG 3DWLHQWVZLWK9RQ+LSSHO/LQGDXGLVHDVHZHUHH[FOXGHG7KHPHGLDQGLDPHWHURI WKHF\VWVZDVFP UDQJHದFP 7KHPHGLDQDJHRISDWLHQWVZDV \HDUV \U $%RVQLDN,,)ZDVVFRUHGLQF\VWVRIZKLFKZHUHEHQLJQ DQG VKRZHG D SDSLOODU\ 5&& RQ SDWKRORJ\ $ %RVQLDN ,,, ZDV VFRUHG LQ FDVHVRIZKLFK Q ZDVDQ5&&$%RVQLDN,9ZDVVFRUHGLQF\VWV DQG RIWKHVHZHUH5&&2QHF\VWVZDVVKRZQWREHFKURQLFLQᚐDPPDWLRQ 7DEOH 7DEOH 1 %RVQLDN,,) Q %RVQLDN,,, Q %RVQLDN,9 Q
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421
IMMUNOPET IMAGING OF RENAL CELL CARCINOMA WITH 124I- AND 89ZR-LABELED ANTI-CAIX MONOCLONAL ANTIBODY CG250
6WLOOHEURHU$)UDQVVHQ*0%RHUPDQ2&2RVWHUZLMN(/DYHUPDQ3 2\HQ:-*0XOGHUV3)$ 1 Radboud University Nijmegen Medical Centre, Dept. of Urology, Nijmegen, The Netherlands, 2Radboud University Nijmegen Medical Centre, Dept. of Nuclear Medicine, Nijmegen, The Netherlands Introduction & Objectives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aterial & Methods: 1XGHPLFH SHUJURXS ZLWKGLᚎHUHQWVFRULSFF5&& [HQRJUDIWV 6.5& 18 ZHUH LY LQMHFWHG ZLWK 0%T =UF* 0%T ,F*RU0%T ))'*7RGHWHUPLQHVSHFLᚏFLW\RIF*XSWDNHLQ FF5&&RQHJURXSRIPLFHZDVLYLQMHFWHGZLWK0%T =U023& LUUHOHYDQW P$E 3(7 LPDJHV ZHUH DFTXLUHG XVLQJ D GHGLFDWHG VPDOO DQLPDO3(7 FDPHUD 6LHPHQV ,QYHRQ GLUHFWO\ DQG GD\V SL 0LFH ZHUH NLOOHG DIWHU WKH ODVW LPDJLQJVHVVLRQDQGWKHFRQFHQWUDWLRQRIWKHUDGLRODEHOHGP$ELQWKHGLVVHFWHG WLVVXHVZDVGHWHUPLQHG
Eur Urol Suppl 2010;9(2):153