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4333937 2-(piperazinyl)-4-pyrimioinamines
New Patents
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4333936
4333940
NOVEL AMIDINOBENZYLPYRIMIDINES, PROCESSES FOR THEIR MANUFACTURE AND ANTIBACTERIAL AND ANTIPROTOZOAL USE THEREOF
RING-FLUORINATED 4(MONOSUBSTITUTED-AMINO) PHENYL COMPOUNDS IN INHIBITING ATHEROSCLEROTIC LESION DEVELOPMENT
P Scharwaechter, K Gutsche, W Kohlmann, G Kroemer, Moorrege, West Germany assigned to BASF Aktiengesellschaft 5-Benzyl-4-amino-pyrimidine-2-amidines which may or may not be substituted in the phenyl ring, and their physiologically acceptable addition salts with acids, processes for their preparation, drugs containing these compounds, and their use in infectious diseases.
R G Shepherd, assigned to American Cyanamid Company
The present invention relates to the use of t certain ring-fluorinated 4-(monosubstituted-amino) phenyl compounds as hypolipidemic and antiatherosclero3,4tic agents together with their pharmacologically acceptable acid-addition and cationic salts.
4333937
2-(PIPERAZINYL)-4PYRIMIOINAMINES S Rakhit, J F Bagli, Dollard des Ormeaux, Canada assigned to American Home Products Corp Herein is disclosed 2-(1-piperazinyl)-4pyrimidinamine derivatives, acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions of the derivatives. The derivatives are distinguished most readily by having novel substituents at position 4 of the piperazinyl radical, the substituents being selected from the group consisting of optionally substituted 2-cycloheptimidazolyl, 1,4,5,6,7, 8-hexahydrocycloheptimidazol-2-yl, 2-benzoxazolyl, benzthiazol-2-yl, 1H-2-benzimid~olyl and 1-oxo2,4, 6-cycloheptarien-2-yl. The derivatives are useful for treating hypertension in a mammal. 4333939
4333941
INHIBITION OF ENVELOPED VIRUSES WITH PHENYL KETONES B S Baratz, R A Phillips, D L Steward, assigned to The Dow Chemical Company
Enveloped viruses such as rhabdoviruses, herpes viruses, influenza viruses, alpha viruses and paramyxo viruses are inactivated by contacting the viruses or virus infected cells with a beta-aminophenylketone compound such as 4-n-butoxy- beta-(l-piperidyl)propiophenone hydrochloride; 3,4-dichloro- beta-(l-piperidyl)propiophenone; 4n-decyloxybeta-( l-piperidyl)propiophenone; or 4-n-butoxy- beta-(N, N-diethylamino)propiophenone.
43339~
ANTI-DEPRESSANT AND ANALGESIC 4-PHENOXYPIPERIDINES
TETRAHYDROPYRIDINYL- INDOLES J Guillaume, L Nedelec, C Dumont, Sevran, France assigned to Roussel Uclaf
K Eistetter, H Kley, H Menge, H Schaefer, Constance, West Germany assigned to BYK Gulden Lomberg Chemische Fabrik GmbH
v
4333936
4333940
NOVEL AMIDINOBENZYLPYRIMIDINES, PROCESSES FOR THEIR MANUFACTURE AND ANTIBACTERIAL AND ANTIPROTOZOAL USE THEREOF
RING-FLUORINATED 4(MONOSUBSTITUTED-AMINO) PHENYL COMPOUNDS IN INHIBITING ATHEROSCLEROTIC LESION DEVELOPMENT
P Scharwaechter, K Gutsche, W Kohlmann, G Kroemer, Moorrege, West Germany assigned to BASF Aktiengesellschaft 5-Benzyl-4-amino-pyrimidine-2-amidines which may or may not be substituted in the phenyl ring, and their physiologically acceptable addition salts with acids, processes for their preparation, drugs containing these compounds, and their use in infectious diseases.
R G Shepherd, assigned to American Cyanamid Company
The present invention relates to the use of t certain ring-fluorinated 4-(monosubstituted-amino) phenyl compounds as hypolipidemic and antiatherosclero3,4tic agents together with their pharmacologically acceptable acid-addition and cationic salts.
4333937
2-(PIPERAZINYL)-4PYRIMIOINAMINES S Rakhit, J F Bagli, Dollard des Ormeaux, Canada assigned to American Home Products Corp Herein is disclosed 2-(1-piperazinyl)-4pyrimidinamine derivatives, acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions of the derivatives. The derivatives are distinguished most readily by having novel substituents at position 4 of the piperazinyl radical, the substituents being selected from the group consisting of optionally substituted 2-cycloheptimidazolyl, 1,4,5,6,7, 8-hexahydrocycloheptimidazol-2-yl, 2-benzoxazolyl, benzthiazol-2-yl, 1H-2-benzimid~olyl and 1-oxo2,4, 6-cycloheptarien-2-yl. The derivatives are useful for treating hypertension in a mammal. 4333939
4333941
INHIBITION OF ENVELOPED VIRUSES WITH PHENYL KETONES B S Baratz, R A Phillips, D L Steward, assigned to The Dow Chemical Company
Enveloped viruses such as rhabdoviruses, herpes viruses, influenza viruses, alpha viruses and paramyxo viruses are inactivated by contacting the viruses or virus infected cells with a beta-aminophenylketone compound such as 4-n-butoxy- beta-(l-piperidyl)propiophenone hydrochloride; 3,4-dichloro- beta-(l-piperidyl)propiophenone; 4n-decyloxybeta-( l-piperidyl)propiophenone; or 4-n-butoxy- beta-(N, N-diethylamino)propiophenone.
43339~
ANTI-DEPRESSANT AND ANALGESIC 4-PHENOXYPIPERIDINES
TETRAHYDROPYRIDINYL- INDOLES J Guillaume, L Nedelec, C Dumont, Sevran, France assigned to Roussel Uclaf
K Eistetter, H Kley, H Menge, H Schaefer, Constance, West Germany assigned to BYK Gulden Lomberg Chemische Fabrik GmbH