XV
New Patents
tion; with the proviso that when Q is other than a benzene ring, R1 and R2 are methyl groups, are disclosed as having action as histamine H2antagonists.
ticulated flaps adapted to be folded against the ends of each support for reinforcing the rectangular cross section.
4451447
4450877 PHARMACEUTICAL PREPARATIONS IN SOLID UNIT DOSAGE FORM Stephen E Walker, Keit Bedford, Terenc Eaves, Buckingham, United Kingdom assigned to Hoechst Aktiengesellschaft
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PHARMACEUTICAL FORMULATIONS Murray Kaplan, Alphonse Granatek assigned to Bristol-Myers Company Stable concentrated solutions of cisplatin in a solvent comprising polyethylene glycol or methoxy polyethylene glycol, or a mixture thereof, plus water and a nontoxic pharmaceutically acceptable source of chloride ion.
4451449 ........ . - ' ~'~.~. 3"- r~-L23 i,. lt.
A process for the manufacture of pharmaceutical preparations in hard capsule form and a capsule filing machine equipped with a detector system and a filling head suitable for dosing a liquid.
XANTHINE DERIVATIVES, AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS Joachim E Goring, Gronau, Federal Republic Of Germany assigned to Wuelfing Johanna CH3 CH3(CH2)3.N ~ . t
CH2~ IC--OR I IN IOR2
4450965 o
CONTAINER FOR PHARMACEUTICAL AMPULES OR THE LIKE Bernard Paillet, Saint Marcel Bel Accueil, France assigned to Compagnie Francaise d'Emballages et de Conditionnement - COFREC "\
N
I
(CH2)3CH3
Ketals of 1-(1,3-dialkylxanthin-7-yl)propan-2ones are of use in the treatment of vascular disorders. A representative embodiment is 2methyl-2-(1,3-dibutylxanthin-7-ylmethyl)-1,3dioxalane.
4451452 PHARMACEUTICAL COMPOSITIONS CONTAINING BIODEGRADABLE POLYMERS
A container for pharmaceutical ampules is formed from a cardboard blank and including hollow lateral supports of rectangular cross section. Such cross section provides a series of parallel openings into which the ends of the ampules are placed. Each support includes a plurality of ar-
Heinrich Deibig, Roland Reiner, Hendricus B A WeUe, Frankfurt, Federal Republic Of Germany assigned to Sandoz Ltd Polymers formed by incomplete esterification of the hydroxy groups of a water-soluble polymer such as polyvinyl alcohol, amylose or dextran with a pharmacologically acceptable mono- or