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4464355 Serum-free and mitogen-free T-cell growth factor and process for making same
PATEST ABSIRACTS
40.
tmuous basis. If desired, at least portions of the treated blood mav then be separated, as lbr example by a continuous centrifuge, before returning the remaining dwerted blood to the subject.
4464355 SERUM-FREE AND MITOGENFREE T-CELL GROWTH FACTOR AND PROCESS FOR MAKING SAME Hans-Ake Fabricius, Roland Stahn, Breisach, Federal Republic Of Germany assigned to Hooper Trading Co A serum-free and mitogen-free T-cell growth factor which is effective in stimulating natural killer cell function in tumor patients is provided. A method of producing the growth factor from human, bovine or porcine spleen or blood is described.
4464362 TOPICAL SKIN REPAIR COMPOSITION Martin Kludas. Dieter Heise, Berlin, Federal Republic Of Germany assigned to Estee Lauder lnc Cosmetic compositions containing an active substance complex for promoting the DNA repair process of the skin cells, in order to guard against possible cellular skin damage due to excessive light influence, and to counteract the light-caused aging process of the skin. The active substance complex consists of inactivated cultures of bacteria of the genus Bifidobacterium or bacteria related to this genus.
4464470 REPLICATION OF VIRULENT T R E P O N E M A P A L L I D U M IN TISSUE CULTURE A Howard Fieldsteel, David L Cox. Randolph A Moeckli assigned to SRI International A method and materials are provided for replication of virulent Treponema pallidum in tissue culture, employing a modified Eagle's minimum essential medium, wherein said in vitro cultivated T. pallidum can be utilized as a source of relatively pure organisms, free of host tissue, for the preparation of a vaccine against syphilis and as a source of organisms for use in specific immunological tests for syphilis.
4464474 NON-A, NON-B HEPATITIS ASSAY AND VACCINE Pierre k Coursaget. Philippe C Maupas, Saint Avertin. France assigned to Connaught Laboratories Limited A newly discovered particle in the urine and serum of non-A, non-B hepatitis patients has been associated with non-A, non-B hepatitis. The particle resembles a togavirus and is 50-60 nm in diameter with a discrete core of about 40 nm in diameter. The virus loses its infectivity for tissue culture upon heating at 25 degrees C. in aqueous suspension or by exposure to ether. The particle may be cultured in vitro or recovered from body fluids or tissues to make immunoassays and vaccines. The immunoassays may be employed to detect the particle antigens or antibodies thereto in test samples.
4464395 4465574 ANTIHYPERTENSIVE C O M P O U N D 176
BLOOD FRACTIONATION IMPROVEMENT
Leeyuan Huang assigned to Merck & Co lnc Antihypertensive compound 176 is a natural product amino acid produced by cultivation of a Streptomyces species under controlled aerobic fermentation conditions. The product is also shown to inhibit angiotensin converting enzyme.
Patric Mattock, Gordan Aitchison. Oxford, United Kingdom assigned to United Kingdom Atomic Energy Authority The extraction of Factor VIII, the antihaemophilic factor in blood, is dilficult due to its
40.
tmuous basis. If desired, at least portions of the treated blood mav then be separated, as lbr example by a continuous centrifuge, before returning the remaining dwerted blood to the subject.
4464355 SERUM-FREE AND MITOGENFREE T-CELL GROWTH FACTOR AND PROCESS FOR MAKING SAME Hans-Ake Fabricius, Roland Stahn, Breisach, Federal Republic Of Germany assigned to Hooper Trading Co A serum-free and mitogen-free T-cell growth factor which is effective in stimulating natural killer cell function in tumor patients is provided. A method of producing the growth factor from human, bovine or porcine spleen or blood is described.
4464362 TOPICAL SKIN REPAIR COMPOSITION Martin Kludas. Dieter Heise, Berlin, Federal Republic Of Germany assigned to Estee Lauder lnc Cosmetic compositions containing an active substance complex for promoting the DNA repair process of the skin cells, in order to guard against possible cellular skin damage due to excessive light influence, and to counteract the light-caused aging process of the skin. The active substance complex consists of inactivated cultures of bacteria of the genus Bifidobacterium or bacteria related to this genus.
4464470 REPLICATION OF VIRULENT T R E P O N E M A P A L L I D U M IN TISSUE CULTURE A Howard Fieldsteel, David L Cox. Randolph A Moeckli assigned to SRI International A method and materials are provided for replication of virulent Treponema pallidum in tissue culture, employing a modified Eagle's minimum essential medium, wherein said in vitro cultivated T. pallidum can be utilized as a source of relatively pure organisms, free of host tissue, for the preparation of a vaccine against syphilis and as a source of organisms for use in specific immunological tests for syphilis.
4464474 NON-A, NON-B HEPATITIS ASSAY AND VACCINE Pierre k Coursaget. Philippe C Maupas, Saint Avertin. France assigned to Connaught Laboratories Limited A newly discovered particle in the urine and serum of non-A, non-B hepatitis patients has been associated with non-A, non-B hepatitis. The particle resembles a togavirus and is 50-60 nm in diameter with a discrete core of about 40 nm in diameter. The virus loses its infectivity for tissue culture upon heating at 25 degrees C. in aqueous suspension or by exposure to ether. The particle may be cultured in vitro or recovered from body fluids or tissues to make immunoassays and vaccines. The immunoassays may be employed to detect the particle antigens or antibodies thereto in test samples.
4464395 4465574 ANTIHYPERTENSIVE C O M P O U N D 176
BLOOD FRACTIONATION IMPROVEMENT
Leeyuan Huang assigned to Merck & Co lnc Antihypertensive compound 176 is a natural product amino acid produced by cultivation of a Streptomyces species under controlled aerobic fermentation conditions. The product is also shown to inhibit angiotensin converting enzyme.
Patric Mattock, Gordan Aitchison. Oxford, United Kingdom assigned to United Kingdom Atomic Energy Authority The extraction of Factor VIII, the antihaemophilic factor in blood, is dilficult due to its