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PATENT ABSTRACTS
4543331 FERMENTATIVE
OR ENZYMATIC
P R O D U C T I O N OF 2-KETO-LGULONIC
ACID
Antibiotic LL-D42067 alpha derived by aerobic fermentation of the microorganism Actinomadura madurae subspecies simaoensis NRRL 15734, useful as an antibacterial and antiparasitic agent.
Takayasu Sonoyama, Shigeo Yagi, Bunji Kageyama, Osaka, Japan assigned to Shionogi & Co Ltd Fermentative or enzymatic production of 2keto-L-gulonic acid from 2, 5-diketo-D-gluconic acid using living or processed mutants, being defective in metabolizing 5-keto-D-gluconic acid and incapable of producing 2-keto-D-gluconic acid. The mutant is derived from 2-keto-Lgluconic acid producing microorganisms of genus Corynebacterium. The production is carried out in the presence of nitrates and/or hydrogen donors in a preliminarily sterilized fermentation broth in which a 2, 5-diketo-Dgluconic acid producing microorganism of genus Gluconobacter or Erwinia has been cultivated.
4548974 ANTIBIOTICS PRODUCED BY KIBDELOSPORANGIUM ARIDUM SHEARER
4554390 METHOD
FOR HARVESTING ALGAE
Cyril C Curtain, Harve Snook, Williamstown, Australia assigned to Commonwealth Scientific and Industrial Research Organization; Betatene Limit A method for harvesting algae of the genus Dunaliella from suspensions thereof in brines containing sodium chloride at a concentration of about 3M or above, wherein the algal suspension is contacted with an adsorbent having a hydrophobic surface so as to adsorb the algae thereon, and the adsorbent with the algae adsorbed thereon is separated from the brine, betacarotene and other useful cell components may be extracted from the adsorbed algae by treatment with a suitable solvent.
Betty Bowie, David J Newman, Marcia Shearer, Robert Sitrin, Joseph Valenta assigned to SmithKline Beckman Corporation 4556073 A novel antibiotic complex of Vancomycin-like antibiotics, AAD 216 complex, is produced by the cultivation of a fermentation broth containing Kibdelosporangium aridum Shearer gen. nov., sp. nov. ATCC 39323 microorganisms in an aqueous nutrient medium under submerged aerobic conditions. The AAD 216 complex and its major bioactive components; AAD 216A, AAD 216B, and AAD 216C exhibit antibiotic activity and growth promotant activity.
4551533 ANTIBIOTIC
LL-D42067 ALPHA
Taikwang M Lee, Donald B Borders, Joseph J Goodman, Raymond T Testa, William M Maiese, David Labeda assigned to American Cyanamid Company
PROCESS FOR REDUCTION OF NITRATE CONTENT OF TOBACCO BY MICROBIAL TREATMENT Lawrence Gravely, Vernon Geiss, Charles Gregory assigned to Brown & Williamson Tobacco Corporation A process for the reduction of the nitrate content of tobacco materials by microbial treatment is disclosed wherein tobacco materials are subjected, under controlled conditions, to the action of a microorganism effective to degrade nitrates through a biochemical reaction. Tobacco materials treated in accordance with this process, when incorporated into a tobacco smoking product, produce a mild smoke having reduced nitrogen oxides and hydrogen cyanide deliveries without loss of desirable flavor, taste or other smoking properties.