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4569943 Physiologically active substance P-23924, its production and use
N e w Patents
features of this LBN-cytoplasm are described and discussed.
4569840 THYMIDINE KINASE-NEGATIVE TEMPERATURE RESISTANT BOVINE HERPESVIRUS-1 MUTANT AS A VACCINE AGAINST INFECTIOUS BOVINE RHINOTRACHEITIS Sau Kit assigned to Baylor College of Medicine; NovaGene Ltd Described are thymidine kinase negative temperature resistant mutants of bovine herpesvirus effective in inducing resistance to infectious bovine rhinotracheitis, methods for their production, methods for maintaining them in viable form, and methods for administering them to animals in immunologically effective doses to induce resistance to infectious bovine rhinotracheitis.
4569908
v
The aspartase from a mutant Bacillus subtilis, NRRL B-15536, is produced in relatively high cell yield within a comparatively short time. The enzyme converts fumaric acid to L-aspartic acid stoichiometrically with outstanding selectivity and productivity. The enzyme is stabilized by divalent magnesium ions, 2-mercaptoethanol, and ammonium furmarate, and can be conveniently purified with high recovery.
4569943 PHYSIOLOGICALLY ACTIVE S U B S T A N C E P-23924, I T S PRODUCTION AND USE Hisayoshi Okazaki, Kazuhiko Ohta, Takenori Ishimaru, Kyoto, Japan assigned to Takeda Chemical Industries Ltd The compound of the formula: See Patent jor Chemical Structure wherein R1 is hydrogen, methyl or hydroxymethyl, R2 is hydrogen or methoxy, R3 is hydroxy or methoxy, and R4 is hydrogen or a group See Patent jbr Chemical Structure is novel, and the compound is of use as inhibitors of animal tissue fibrosis, or biochemical reagents.
MULTICLASS HYBRID INTERFERONS 4570212 David F Mark, Abla A Creasey assigned to Cetus Corporation New multiclass hybrid interferon polypeptides, their corresponding encoding recombinant DNA molecules and transformed hosts which produce the new interferons are described. The amino acid sequences of these hybrids include at least two different subsequences, one of which has substantial homology with a portion of a first class of interferon (e.g., HuIFN- alpha) and the other which has substantial homology with a portion of a second class of interferon e.g., HuIFN- beta). Data indicates the interferon activity of alpha- beta hybrids may be substantially restricted to either cell growth regulatory activity or antiviral activity.
4569911 METHOD OF MAKING ASPARTIC ACID AND PURIFYING ASPARTASE Yoshihisa Tsuda assigned to UOP Inc
SILICON CONTROLLED RECTIFIER POLYPHASE BRIDGE INVERTER COMMUTATED WITH GATE-TURN-OFF THYRISTOR Dean B Edwards, Wally E Rippel assigned to California Institute of Technology A polyphase SCR inverter (10) having N switching poles, each comprised of two SCR switches (1 A, 1B; 2A, 2B... NA, NB) and two diodes (DIB; DIB; D2A, D2B... DNA, DNB) in series opposition with saturable reactors (L1A, LIB; L2A, L 2 B . . . LNA, LNB) connecting the junctions between the SCR switches and diodes to an output terminal (1, 2 . . . 3) is commutated with only one GTO thyristor (16) connected between the common negative terminal ofa dc source and a tap of a series inductor (14) connected to the positive terminal of the dc source. A clamp winding (22) and diode (24) are provided, as is a snubber (18) which may have its capacitance (c) sized for maximum load current divided into a plurality of capacitors (C1, C 2 . . . CN), each in series with an SCR switch S1, $2 . . . SN). The total capacitance may be selected by activating
features of this LBN-cytoplasm are described and discussed.
4569840 THYMIDINE KINASE-NEGATIVE TEMPERATURE RESISTANT BOVINE HERPESVIRUS-1 MUTANT AS A VACCINE AGAINST INFECTIOUS BOVINE RHINOTRACHEITIS Sau Kit assigned to Baylor College of Medicine; NovaGene Ltd Described are thymidine kinase negative temperature resistant mutants of bovine herpesvirus effective in inducing resistance to infectious bovine rhinotracheitis, methods for their production, methods for maintaining them in viable form, and methods for administering them to animals in immunologically effective doses to induce resistance to infectious bovine rhinotracheitis.
4569908
v
The aspartase from a mutant Bacillus subtilis, NRRL B-15536, is produced in relatively high cell yield within a comparatively short time. The enzyme converts fumaric acid to L-aspartic acid stoichiometrically with outstanding selectivity and productivity. The enzyme is stabilized by divalent magnesium ions, 2-mercaptoethanol, and ammonium furmarate, and can be conveniently purified with high recovery.
4569943 PHYSIOLOGICALLY ACTIVE S U B S T A N C E P-23924, I T S PRODUCTION AND USE Hisayoshi Okazaki, Kazuhiko Ohta, Takenori Ishimaru, Kyoto, Japan assigned to Takeda Chemical Industries Ltd The compound of the formula: See Patent jor Chemical Structure wherein R1 is hydrogen, methyl or hydroxymethyl, R2 is hydrogen or methoxy, R3 is hydroxy or methoxy, and R4 is hydrogen or a group See Patent jbr Chemical Structure is novel, and the compound is of use as inhibitors of animal tissue fibrosis, or biochemical reagents.
MULTICLASS HYBRID INTERFERONS 4570212 David F Mark, Abla A Creasey assigned to Cetus Corporation New multiclass hybrid interferon polypeptides, their corresponding encoding recombinant DNA molecules and transformed hosts which produce the new interferons are described. The amino acid sequences of these hybrids include at least two different subsequences, one of which has substantial homology with a portion of a first class of interferon (e.g., HuIFN- alpha) and the other which has substantial homology with a portion of a second class of interferon e.g., HuIFN- beta). Data indicates the interferon activity of alpha- beta hybrids may be substantially restricted to either cell growth regulatory activity or antiviral activity.
4569911 METHOD OF MAKING ASPARTIC ACID AND PURIFYING ASPARTASE Yoshihisa Tsuda assigned to UOP Inc
SILICON CONTROLLED RECTIFIER POLYPHASE BRIDGE INVERTER COMMUTATED WITH GATE-TURN-OFF THYRISTOR Dean B Edwards, Wally E Rippel assigned to California Institute of Technology A polyphase SCR inverter (10) having N switching poles, each comprised of two SCR switches (1 A, 1B; 2A, 2B... NA, NB) and two diodes (DIB; DIB; D2A, D2B... DNA, DNB) in series opposition with saturable reactors (L1A, LIB; L2A, L 2 B . . . LNA, LNB) connecting the junctions between the SCR switches and diodes to an output terminal (1, 2 . . . 3) is commutated with only one GTO thyristor (16) connected between the common negative terminal ofa dc source and a tap of a series inductor (14) connected to the positive terminal of the dc source. A clamp winding (22) and diode (24) are provided, as is a snubber (18) which may have its capacitance (c) sized for maximum load current divided into a plurality of capacitors (C1, C 2 . . . CN), each in series with an SCR switch S1, $2 . . . SN). The total capacitance may be selected by activating