4591552 Detection of hepatitis B surface antigen (or antibody to same) with labeled synthetic peptide

4591552 Detection of hepatitis B surface antigen (or antibody to same) with labeled synthetic peptide

Molecu/ar Pergamon Immunology, Vol. 24, No. 2, pp. i-iii, 1987 Journals Ltd. Printed in Great Britain. NEW PATENTS This Section contains abstracts (...

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Molecu/ar Pergamon

Immunology, Vol. 24, No. 2, pp. i-iii, 1987 Journals Ltd. Printed in Great Britain.

NEW PATENTS This Section contains abstracts (without graphics) of recently issued United States patents and published patent applications filed from over 30 countries under the Patent Cooperation Treaty. This information was obtained from recent additions to the Pergamon PATSEARCHx online database in accordance with interest profiles developed by the Editors. Further information about Pergamon PATSEARCH% can be obtained from Pergamon InfoLine Inc., 1340 Old Chain Bridge Road, McLean, Virginia 22101 U.S.A. Copies of complete patents announced in this Section are available from Pergamon InfoLine Inc. for $8 per copy. Pavment with order is reauired. Orders outside North America add $2 for air postage. Order by patent number for Pergamon InfoLine only.

4590072

stimulate cell-mediated immune responses without stimulating synthesis of gamma E globulin and gamma G globulin. The polyanionic polysaccharide may be injected along to stimulate cell-mediated immune responses to antigens in a diseased subject.

LIVE VACCINE FOR BOVINE BABESIOSIS AND METHOD OF PREPARATION Gerald Buening, Charles Carson assigned to Curators of the University of Missouri

4591552

A live vaccine for bovine babesiosis comprises viable bovine erythrocytes parasitized with a cloned population of Babesia bovis, the clone strain being fast-growing, avirulent, and producing a mild but immunizing infection when administered. The vaccine is free of slowgrowing virulent B. bovis. The clone strain used in the vaccine is prepared from a natural mixture of virulent and avirulent babesia by progressive dilution culturing to obtain cultures containing single parasites, propagating the single parasites under favorable conditions for growth, and selecting a fast-growing avirulent clone line for either in vitro or in vivo propagation to prepare the vaccines.

DETECTION OF HEPATITIS B SURFACE ANTIGEN (OR ANTIBODY TO SAME) WITH LABELED SYNTHETIC PEPTIDE A Rober Neurath assigned to New York Blood Center Inc A radiolabeled or enzyme labeled peptide having no more than 60 amino acids in the chain of the peptide; the peptide having covalently linked amino acids disposed in a steric configuration which is recognized by and bound by an antibody. The labeled peptides can be utilized in various processes to detect the presence of a given antibody or antigen in a sample. Hepatitis B surface antigen and antibody to same may be so detected.

4590181 SYNTHETIC IMMUNOREGULATORS AND METHODS OF USE AND PREPARATION

4591558 NOVEL SUBSTANCES HAVING ANTITUMOR AND IMMUNOSTIMULATING ACTIVITY, PROCESS FOR PREPARING THE SAME AND ANTITUMOR AGENT CONTAINING THE SAME

Robert E McCarthy assigned to Board of Regents of the University of Nebraska To regulate the immune response to an antigen, a subject is injected with the antigen and a polyanionic polysaccharide derivative having a molecular weight of between 10,000 and 600,000 selected to correspond to the antigen. For virus, as an example, mycodextran sulfate or pustulan sulfate may be used in sufficient quantities to

Kenzo Tamai, Isam Saikawa, Takash Yasuda, Shohachi Murakami, Toyoo Maeda, Hisatsugu i