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475 EVALUATION AND CLINICAL APPLICATION OF THE UROLIZER®-DEVICE FOR DETERMINATION OF THE BONN-RISK-INDEX OF CALCIUM OXALATE STONE FORMATION
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EVALUATION AND CLINICAL APPLICATION OF THE UROLIZER®-DEVICE FOR DETERMINATION OF THE BONN-RISK-INDEX OF CALCIUM OXALATE STONE FORMATION
%HFKOHU5%HUJ::XQGHUOLFK+/DXEH1 1 Friedrich-Schiller-University of Jena, Dept. of Urology, Jena, Germany, 2 Kaiserslautern University, Institute of Thin Film Technology, Bonn, Germany Introduction & Objectives: 7KH%2115LVN,QGH[ %5, VXFFHVVIXOO\GHWHUPLQHV WKH FDOFLXP R[DODWH &D2[ FU\VWDOOL]DWLRQ ULVN IURP XULQH VDPSOHV 7KH %5, LV EDVHG RQ D VWDQGDUGL]HG FU\VWDOOL]DWLRQ WHVW SHUIRUPHG RQ QDWLYH XULQH $ %5, PHDVXULQJ GHYLFH WKH ಫಫ8UROL]HUpಬಬ ZDV GHYHORSHG RSHUDWLQJ DXWRPDWLFDOO\ DQG UHTXLULQJ RQO\ D PLQLPXP RI SUHSDUDWLYH HᚎRUWV ,Q WKLV VWXG\ WKH 8UROL]HUp ZDV WHVWHGLQUHVSHFWWRLWVSUHFLVLRQDQG HYDOXDWHGUHJDUGLQJLWVDQDO\WLFDODQG GLDJQRVWLF SUDFWLFDELOLW\ IRU PHWDSK\OD[LV FRQWURO LQ WKH IUDPHZRUN RI WKH GDLO\ URXWLQHRIDVWRQHVXUJHU\)XUWKHUPRUHWKHLQᚐXHQFHRIXULQHVWRUDJHDWPRGHUDWH WHPSHUDWXUHVRQ%5,ZDVLQYHVWLJDWHG Material & Methods: KXULQHV IURP UHFXUUHQW &D2[ VWRQHIRUPHUV 6) ZHUH FROOHFWHG DQG URXWLQH XULQDO\VHV SHUIRUPHG XULQH VDPSOHV ZHUH XVHG IRU WKH LQYHVWLJDWLRQ RI 8UROL]HUp SUHFLVLRQ E\ SHUIRUPLQJ VL[ LQGHSHQGHQW %5, GHWHUPLQDWLRQVLQVHULHV)URP6)KXULQHVZHUHFROOHFWHGDWWKHEHJLQQLQJ DQG DIWHU PRQWKV RI PHWDSK\OD[LV :LWK WKH UHVXOWV REWDLQHG IURP WKH ᚏUVW XULQDO\VLV SDWLHQWV ZHUH LQGLFDWHG WR VXᚎHU IURP PLOG K\SHUFDOFLXULD &D PPROG ORZXULQDU\S+RUK\SRFLWUDWXULDDQGSDWLHQWVIURPK\SHUFDOFLXULD &D !PPROG 7KHIRUPHUZHUHWUHDWHGZLWKDONDOLQHFLWUDWH $& DQGWKHODWWHU ZLWK K\GURFKORURWKLD]LGH +&7 $QDO\VHV RI XULQHV FROOHFWHG EHIRUH DQG GXULQJ WUHDWPHQW %5, XVLQJ WKH 8UROL]HUp DQG XULQDO\VLVEDVHG ULVN LQGLFHV ZHUH HYDOXDWHG VDPSOHV ZHUH WDNHQ IRU LQYHVWLJDWLRQ RI XULQH VWRUDELOLW\ DQG ZHUH PHDVXUHG WKULFH GLUHFWO\ DIWHU FROOHFWLRQ DIWHU K VWRUDJH DW 7 r& DQG DIWHU KFRROLQJDW7 r&2XWFRPHVZHUHVWDWLVWLFDOO\WHVWHGIRULGHQWLW\ZLWKUHJDUGWR WKHLPPHGLDWHO\REWDLQHGUHVXOWV Results: 5HSHDW PHDVXUHPHQWV IRU HYDOXDWLRQ RI 8UROL]HUp SUHFLVLRQ UHYHDOHG VWDWLVWLFDO LGHQWLW\ RI GDWD S 9& 3DVVLQJ%DEORFN ,Q ERWK SDWLHQW JURXSV %5, GHFUHDVHG VLJQLᚏFDQWO\ GXULQJ PHWDSK\OD[LV S :LOFR[RQ 7HVW ,Q WKH $&JURXS %5, GHFUHDVHG IURP s WR s / DQG LQ WKH +&7JURXS IURP s WR s / ,Q PRVW SDWLHQWV XULQDU\ SDUDPHWHUVFKDQJHGDVGHVLUHGDQGUHODWHGULVNLQGLFHV HJ$3 &D2[ GHFUHDVHG DSSURSULDWHO\KVWRUDJHRIXULQHDWERWKWHVWHGWHPSHUDWXUHVGLGQRWVLJQLᚏFDQWO\ DᚎHFW%5, S %ODQG$OWPDQQ3DVVLQJ%DEORFN Conclusions: 7KHSLORWUXQ8UROL]HUpVKRZVKLJKDQDO\WLFDOUHOLDELOLW\WKHFOLQLFDO XWLOLW\RI8UROL]HUpEDVHG%5,LVGHPRQVWUDWHG%\TXDQWLI\LQJWKHಫಫRYHUDOOಬಬWKHUDS\ HᚎHFWZLWKLQPLQXWHVWKHDQDO\VLVGHYLFHPD\EHHVSHFLDOO\VXLWHGIRUXURORJLVWV VSHFLDOL]LQJLQXUROLWKLDVLVWUHDWPHQW7KHSRVVLELOLW\IRUXULQHVWRUDJHDWPRGHUDWH WHPSHUDWXUHVZLWKRXWORVVRIDQDO\VLVTXDOLW\IXUWKHUGHPRQVWUDWHVWKHDSSOLFDELOLW\ RIWKH%5,PHWKRG
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RELATIONSHIP BETWEEN NEPHROLITHIASIS AND COMPONENTS OF METABOLIC SYNDROME IN KOREAN ADULTS
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.QROO7'H/D5RVHWWH---RFKDP'/DJXQD3/LHGEHUJ) 0DQQVRQ:5DVVZHLOHU-55LHGOHU,5RFFR)6LHPHU6 :HQGW1RUGDKO*=LJHXQHU5$ONHQ3(XURSHDQ,QWUDUHQDO6XUJHU\6RFLHW\ 1 Sindelfingen-Böblingen Medical Center, Dept. of Urology, Sindelfingen, Germany, 2Academic Medical Center University of Amsterdam, Dept. of Urology, Amsterdam, The Netherlands, 3University Hospital Schleswig-Holstein Campus Lübeck, Dept. of Urology, Lübeck, Germany, 4Växjö County Hospital, Dept. of Urology, Växjö, Sweden, 5University Hospital Lund, Dept. of Urology, Lund, Sweden, 6Slk Klinikum Heilbronn, Dept. of Urology, Heilbronn, Germany,
475
EVALUATION AND CLINICAL APPLICATION OF THE UROLIZER®-DEVICE FOR DETERMINATION OF THE BONN-RISK-INDEX OF CALCIUM OXALATE STONE FORMATION
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476
NUTRITIONAL, ENVIRONMENTAL AND FAMILY HISTORY DETERMINANTS OF RECURRENT NEPHROLITHIASIS VERSUS PRIMARY NEPHROLITHIASIS
5HQWVFKOHU$2HKOVFKO¦JHU6:LUWK03 Technical University Dresden, Dept. of Urology, Dresden, Germany Introduction & Objectives: 7KHSUHYDOHQFHRIQHSKUROLWKLDVLVDPRXQWVWKH LQFLGHQFHLVDERXWLQ*HUPDQ\7KHSURSRUWLRQRIUHFXUUHQWQHSKUROLWKLDVLV DIWHU SULPDU\ WKHUDS\ ZLWKRXW VSHFLᚏF SRVWRSHUDWLYH WUHDWPHQW DFFRXQWV IRU XS WR ZLWKLQ VHYHQ \HDUV 0HWDEROLF V\QGURPH GLDEHWHV PHOOLWXV DUWHULDO K\SHUWHQVLRQDGLSRVLW\ DQGQHSKUROLWKLDVLVDUHTXLWHFRPPRQGLVRUGHUV7KHIRRG SDWWHUQDQGWKHSHUVRQDOFLUFXPVWDQFHVLQᚐXHQFHWKHLQFLGHQFHRIQHSKUROLWKLDVLV 7KH DLP RI WKLV VWXG\ ZDV WR H[DPLQH WKH HᚎHFWV RI QXWULWLRQDO HQYLURQPHQWDO IDPLO\KLVWRU\DQGPHGLFDOIDFWRUVRQUHFXUUHQWYHUVXVSULPDU\QHSKUROLWKLDVLV Material & Methods: %HWZHHQ -DQ DQG $XJ SDWLHQWV ZHUH H[DPLQHGZLWKSULPDU\ DQGUHFXUUHQW QHSKUROLWKLDVLVZLWKDVWDQGDUGL]HG TXHVWLRQQDLUH +HVVHHWDO :HDQDO\VHGDJH%0,VH[IDPLO\KLVWRU\VWRQH KLVWRU\ DUWHULDO K\SHUWHQVLRQ GLDEHWHV PHOOLWXV JRXW 3 $2' DQJLQD SHFWRULV JDVWURLQWHVWLQDO GLVHDVHV VPRNLQJ ZRUNLQJ HQYLURQPHQW GULQNLQJ DPRXQW DQG DOLPHQWDWLRQ IUHTXHQF\ RI DOFRKRO VXJDU PHDW IUXLW DQG YHJHWDEOH DQG GLHW 7KH SUHVHQFH RI QHSKUROLWKLDVLV ZDV DVVHVVHG E\ XOWUDVRXQG DQGRU UDGLRORJLFDO H[DPLQDWLRQRIWKHNLGQH\VDQGXSSHUXULQDU\WUDFW6WDWLVWLFDODQDO\VLVZDVGRQH XVLQJWKH0DQQ:KLWQH\8WHVW Results: 7KHIUHTXHQF\RIPHDWLQJHVWLRQZDVVLJQLᚏFDQWO\LQFUHDVHGLQUHFXUUHQW VWRQH IRUPHUV S %DODQFHG PL[HG GLHW ZDV VLJQLᚏFDQWO\ GHFUHDVHG LQ UHFXUUHQWVWRQHIRUPHUV S
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RELATIONSHIP BETWEEN NEPHROLITHIASIS AND COMPONENTS OF METABOLIC SYNDROME IN KOREAN ADULTS
&KR<6-RR.-3DUN+-.ZRQ&+ Kangbuk Samsung Hospital, Dept. of Urology, Seoul, South Korea Introduction & Objectives: 0HWDEROLFV\QGURPH 06 DQGQHSKUROLWKLDVLV 1/ DUH FRPPRQGLVRUGHUV6RPHRIWKHFRPSRQHQWVRIPHWDEROLFV\QGURPHKDYHEHHQ SURSRVHGDVSUHFXUVRUVRI1/,WLVQRWNQRZQKRZHYHUZKHWKHU06LVDVVRFLDWHG ZLWK FRPSRQHQWV DᚎHFWLQJ 1/ 7KH REMHFWLYH RI WKH VWXG\ ZDV WR HYDOXDWH WKH UHODWLRQVKLSEHWZHHQ1/DQGFRPSRQHQWVRI06LQ.RUHDQDGXOWV Material & Methods: %HWZHHQ -DQXDU\ DQG 'HFHPEHU D WRWDO RI DGXOWVZKRYLVLWHGRXUKHDOWKSURPRWLRQFHQWHUDQGQRSUHYLRXVKLVWRU\RI 1/ZHUHHQUROOHG7KH06GLDJQRVLVZDVSHUIRUPHGDFFRUGLQJWRWKHJXLGHOLQHVRI WKH1DWLRQDO&KROHVWHURO(GXFDWLRQ3URJUDP$GXOW7UHDWPHQW3DQHO,,, 1&(3$73 ,,, 7KHSUHVHQFHRI1/ZDVDVVHVVHGE\XOWUDVRXQGH[DPLQDWLRQRINLGQH\VDQG XSSHUXULQDU\WUDFW Results: 7KH PHDQ DJH ZDV s \HDUV DQG WKH SUHYDOHQFH RI 06 LQ 1/ JURXS DQG RWKHU JURXS ZHUH UHVSHFWLYHO\ S $PRQJ WKH LQGLYLGXDOFRPSRQHQWVRI06DEGRPLQDOREHVLW\KLJKEORRGSUHVVXUHDQG+'/ & KLJKGHQVLW\OLSRSURWHLQFKROHVWHURO ZHUHLQGHSHQGHQWO\UHODWHGWRHFKRJUDSKLF HYLGHQFH RI 1/ 7DEOH 7KH UHVXOWV ZHUH IXUWKHU DQDO\VHG VHSDUDWHO\ LQ PDOH DQG IHPDOH SDUWLFLSDQWV 7KH SUHYDOHQFH RI 06 LQ 1/ JURXS LQ PDOH DQG IHPDOH ZHUHUHVSHFWLYHO\&RPSDUHGWRDQGLQ1/IUHHJURXS WKHUHZDVQRVWDWLVWLFDOO\VLJQLᚏFDQWGLᚎHUHQFH,QDPXOWLYDULDWHORJLVWLFUHJUHVVLRQ PRGHOFHQWUDOREHVLW\DQGK\SHUWHQVLRQZHUHLQGHSHQGHQWULVNIDFWRUVRI1/ RGGV UDWLRUHVSHFWLYHO\ LQIHPDOH:KHQGLYLGHGLQWRWKUHHJURXSV ุ EDVHGRQWKHVXPRI06FRPSRQHQWVWKHRGGUDWLRVZHUHLQJURXSDQG LQ ุ JURXS 7DEOH &RUUHODWLRQ EHWZHHQ IDFWRUV RI PHWDEROLF V\QGURPH DQG QHSKUROLWKLDVLV 1/JURXS
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.QROO7'H/D5RVHWWH---RFKDP'/DJXQD3/LHGEHUJ) 0DQQVRQ:5DVVZHLOHU-55LHGOHU,5RFFR)6LHPHU6 :HQGW1RUGDKO*=LJHXQHU5$ONHQ3(XURSHDQ,QWUDUHQDO6XUJHU\6RFLHW\ 1 Sindelfingen-Böblingen Medical Center, Dept. of Urology, Sindelfingen, Germany, 2Academic Medical Center University of Amsterdam, Dept. of Urology, Amsterdam, The Netherlands, 3University Hospital Schleswig-Holstein Campus Lübeck, Dept. of Urology, Lübeck, Germany, 4Växjö County Hospital, Dept. of Urology, Växjö, Sweden, 5University Hospital Lund, Dept. of Urology, Lund, Sweden, 6Slk Klinikum Heilbronn, Dept. of Urology, Heilbronn, Germany,