479. Retroviral Vector-Mediated Expression of Therapeutic Levels of Canine Factor IX in Adult and Neonatal Mice

!""# #  " " 479. Retroviral V ector-Mediated Expression of Vector-Mediated Therapeutic Levels of Canine Factor IX in Adult and Neonatal Mice Lingfei Xu,1 Mark S. Sands,2 Cuihua Gao,1 Katherine P. Ponder.1 1 Internal Medicine and Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, United States; 2Internal Medicine and Biochemistry and Genetics, Washington University School of Medicine, St. Louis, MO, United States. C   2   F"

 

      

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480. Sustained Correction of Hemophilia B Phenotype Following Intravascular Delivery of AA VV ector to AAV Vector Skeletal Muscle Valder R. Arruda,1 Hansell Stedman,2 Nichols C. Timothy,4 Mark Haskins,3 Joerg Schuettrumpf,1 Roland W. Herzog,1 Yi-Lin Liu,1 Kristi Wagner,1 Linda Couto,5 Katherine A. High.1 1 Pediatrics, The Children′s Hospital of Philadelphia, Philadelphia, PA, United States; 2Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, United States; 3Pathology and Medical Genetics, Univeristy of Pennsylvania School of Veterinary, Philadelphia, PA, United States; 4Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, United States; 5Avigen, Inc., Alameda, CA, United States.   ''.,"



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481. Strain-Specific Differences in the Generation of an Anti-Factor VIII Immune Response in Hemophilic Mice Treated with Adenoviral Gene Therapy Fiona E. M. Grant,1 Brian Brown,1 Chang Xin Shi,2 Frank Graham,2 Shawn Tinlin,1 Alexis McKinven,1 David Lillicrap.1 1 Pathology, Queen′s University, Kingston, ON, Canada; 2Biology, McMaster University, Hamilton, ON, Canada. &;2D%B?.  

 

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