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4818538 Treatment of human viral infections
PATENT
446
also provided a dsDNA sequence encoding the novel polypeptide; a replicable plasmidic expression vehicle containing the dsDNA encoding the novel polypeptides of the invention; a microorganism which has been transformed with the replicable plasmidic expression vehicle; and a method of preparing the dsDNA which encodes the novel polypeptides of the invention.
4818527 T CELL EPITOPES OF THE HEPATITIS B VIRUS NUCLEOCAPSID PROTEIN George Thornton, Ann M Moriarty, David R Milich, Alan McLachlan assigned to Scripps Clinic and Research Foundation Polypeptides correspondmg in amino acid residue sequence to T cell stimulating regions of the HBV nucleocapsid protein are disclosed. A method of enhancing the immunogenicity of a polypeptide immunogen comprising operatively linking the polypeptide through an amino acid residue side chain to core protein particles is also disclosed.
4818528 VACCINE
AGAINST INFECTIOUS BOVINE KERATOCONJUNCTIVITIS
Wallace H Green, Leon N D Potgieter assigned to The University of Tennessee Research Corporation A vaccine for immunizing cattle against infectious bovine keratoconjunctivitis which contains protein fragments having an antigenic site common to pili of pathogenic strains of Moraxella bovis and is produced by reacting purified Moraxella bovis pili with cyanogen bromide.
4818530 PREPARATION OF PELLETS CONTAINING FUNGI FOR CONTROL OF SOILBORNE DISEASES James Marois, Deborah Fravel, William Connick, H Lyn Walker, Paul C Quimby assigned to The United States of America as represented by the Secretary of Agriculture
ABSTRACTS
This invention relates to a method for preparing pellets containing living biocontrol fungi. Fungi are selected and grown for sufficient time to produce inoculum. The fungal propagules are harvested, homogenized and diluted with sodium alginate solution. Pelletization is then accomplished by dropwise addition of the fungal propagule-alginate mixture into a solution of calcium chloride or calcium gluconate. The resultant alginate gel pellets containing living fungi can then be dried and are used to inoculate agricultural fields infested with soilborne plant diseases.
4818538 TREATMENT OF HUMAN VIRAL INFECTIONS Janet Rideout, David W Barry, Sandra N Lehrman, Clair Martha H St, Phillip A Furman assigned to Burroughs Wellcome Co Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the com3’-azido-3’-deoxythymidine or a pound pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5 double bondmono-, di- and triphosphate of 3’-azido-3’pharmaceutically deoxythymidine or a acceptable basic salt thereof for the same purpose.
4818678 DIAGNOSTIC SYSTEM FOR THE DETECTION OF CYTOMEGALOVIRUS Michael B A Oldstone, George Rice assigned to Scripps Clinic and Research Foundation A mammalian monoclonal receptor is produced by a hybridoma formed by fusion of cells from a myeloma cell line and lymphocytes that produce antibodies that react with a viral antigen from a mammal immunized with cytomegalovirusinfected cells. The monoclonal receptor reacts with the viral antigen in a diagnostic system to detect the presence of cytomegalovirus in a biological sample.
446
also provided a dsDNA sequence encoding the novel polypeptide; a replicable plasmidic expression vehicle containing the dsDNA encoding the novel polypeptides of the invention; a microorganism which has been transformed with the replicable plasmidic expression vehicle; and a method of preparing the dsDNA which encodes the novel polypeptides of the invention.
4818527 T CELL EPITOPES OF THE HEPATITIS B VIRUS NUCLEOCAPSID PROTEIN George Thornton, Ann M Moriarty, David R Milich, Alan McLachlan assigned to Scripps Clinic and Research Foundation Polypeptides correspondmg in amino acid residue sequence to T cell stimulating regions of the HBV nucleocapsid protein are disclosed. A method of enhancing the immunogenicity of a polypeptide immunogen comprising operatively linking the polypeptide through an amino acid residue side chain to core protein particles is also disclosed.
4818528 VACCINE
AGAINST INFECTIOUS BOVINE KERATOCONJUNCTIVITIS
Wallace H Green, Leon N D Potgieter assigned to The University of Tennessee Research Corporation A vaccine for immunizing cattle against infectious bovine keratoconjunctivitis which contains protein fragments having an antigenic site common to pili of pathogenic strains of Moraxella bovis and is produced by reacting purified Moraxella bovis pili with cyanogen bromide.
4818530 PREPARATION OF PELLETS CONTAINING FUNGI FOR CONTROL OF SOILBORNE DISEASES James Marois, Deborah Fravel, William Connick, H Lyn Walker, Paul C Quimby assigned to The United States of America as represented by the Secretary of Agriculture
ABSTRACTS
This invention relates to a method for preparing pellets containing living biocontrol fungi. Fungi are selected and grown for sufficient time to produce inoculum. The fungal propagules are harvested, homogenized and diluted with sodium alginate solution. Pelletization is then accomplished by dropwise addition of the fungal propagule-alginate mixture into a solution of calcium chloride or calcium gluconate. The resultant alginate gel pellets containing living fungi can then be dried and are used to inoculate agricultural fields infested with soilborne plant diseases.
4818538 TREATMENT OF HUMAN VIRAL INFECTIONS Janet Rideout, David W Barry, Sandra N Lehrman, Clair Martha H St, Phillip A Furman assigned to Burroughs Wellcome Co Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the com3’-azido-3’-deoxythymidine or a pound pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5 double bondmono-, di- and triphosphate of 3’-azido-3’pharmaceutically deoxythymidine or a acceptable basic salt thereof for the same purpose.
4818678 DIAGNOSTIC SYSTEM FOR THE DETECTION OF CYTOMEGALOVIRUS Michael B A Oldstone, George Rice assigned to Scripps Clinic and Research Foundation A mammalian monoclonal receptor is produced by a hybridoma formed by fusion of cells from a myeloma cell line and lymphocytes that produce antibodies that react with a viral antigen from a mammal immunized with cytomegalovirusinfected cells. The monoclonal receptor reacts with the viral antigen in a diagnostic system to detect the presence of cytomegalovirus in a biological sample.