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4837304 Inhibitor of ribonucleotide reductase
PATENT ABSTRACTS
602
4837171 ANTI-EPIGLYCANIN MONOCLONAL ANTIBODIES John F Codington assigned Hospital Corporation Monoclonal glycanin.
antibodies
to The General
reactive
with
epi-
4837208 TREATMENT OF HUMAN VIRAL INFECTIONS Janet L Rideout, David Barry, Sandra N Lehrman, Clair Martha H St, Phillip A Furman assigned to Burroughs Wellcome Co Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the com.3’-azido-3’-deoxythymidineor a pound pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5’-mono-, di- and triphosphate of 3’-azido-3’-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
4837394 INHIBITOR OF RIBONUCLEOTIDE REDUCTASE Victor M Garsky, Merck & Co Inc
Robert
A Stein assigned to
A series of oligopeptides each of which contains a D-amino acid has been found to inhibit the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication.
4837380 LIPOSOME-CALCITONIN PREPARATION Leonard Deftos, Karl Hostetler assigned to Regents of University of California A liposome-entrapped calcitonin composition and method of use is disclosed. The composition when parenterally administerd to a host mam-
mal, produces an enhanced and prolonged hypocalcemic effect in said mammal and thus is useful in treating diseases related to abnormal skeletal metabolism. The liposomes are substantially free of cholesterol and may be single or multilamellar.
4839275 CIRCULATING ANTIGENS OF DIROFILARIA IMMITIS, MONOCLONAL ANTIBODIES SPECIFIC THEREFOR AND METHODS OF PREPARING SUCH ANTIBODIES AND DETECTING SUCH ANTIGENS Gary J Weil assigned to The Jewish Hospital Novel hybrid cell lines are disclosed for providing monoclonal antibodies to circulating parasite antigens present in the blood of animals infected with the nematode parasite Dirofilaria immitis. Such circulating parasite antigens are also characterized and identified. Further disclosed are methods employed to produce and select such hybrid cell lines and diagnostically useful assay methods utilizing the monoclonal antibodies in the detection of such specific circulating parasite antigens in blood or bodily fluids.
4839288 RETROVIRUS CAPABLE OF CAUSING AIDS, ANTIGENS OBTAINED FROM THIS RETROVIRUS AND CORRESPONDING ANTIBODIES AND THEIR APPLICATION FOR DIAGNOSTIC PURPOSES Luc Montagnier, Denise Guetard, Brim-Vezinet, Francois Clavel, France assigned to Institut Pasteur
Francoise Robinson,
The invention relates to a new variety of retroviruses designated human immunodeficiency virus type II, HIV-II, samples of which have been deposited at CNCM as I-502 and I532. It also concerns purified forms of the antigens which can be obtained from this virus, in particular from the gp 36 and gp 130-140 proteins. These various antigens are useful in medical diagnosis, in particular by being placed in contact with serum of the patient to be dia-
602
4837171 ANTI-EPIGLYCANIN MONOCLONAL ANTIBODIES John F Codington assigned Hospital Corporation Monoclonal glycanin.
antibodies
to The General
reactive
with
epi-
4837208 TREATMENT OF HUMAN VIRAL INFECTIONS Janet L Rideout, David Barry, Sandra N Lehrman, Clair Martha H St, Phillip A Furman assigned to Burroughs Wellcome Co Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the com.3’-azido-3’-deoxythymidineor a pound pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5’-mono-, di- and triphosphate of 3’-azido-3’-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
4837394 INHIBITOR OF RIBONUCLEOTIDE REDUCTASE Victor M Garsky, Merck & Co Inc
Robert
A Stein assigned to
A series of oligopeptides each of which contains a D-amino acid has been found to inhibit the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication.
4837380 LIPOSOME-CALCITONIN PREPARATION Leonard Deftos, Karl Hostetler assigned to Regents of University of California A liposome-entrapped calcitonin composition and method of use is disclosed. The composition when parenterally administerd to a host mam-
mal, produces an enhanced and prolonged hypocalcemic effect in said mammal and thus is useful in treating diseases related to abnormal skeletal metabolism. The liposomes are substantially free of cholesterol and may be single or multilamellar.
4839275 CIRCULATING ANTIGENS OF DIROFILARIA IMMITIS, MONOCLONAL ANTIBODIES SPECIFIC THEREFOR AND METHODS OF PREPARING SUCH ANTIBODIES AND DETECTING SUCH ANTIGENS Gary J Weil assigned to The Jewish Hospital Novel hybrid cell lines are disclosed for providing monoclonal antibodies to circulating parasite antigens present in the blood of animals infected with the nematode parasite Dirofilaria immitis. Such circulating parasite antigens are also characterized and identified. Further disclosed are methods employed to produce and select such hybrid cell lines and diagnostically useful assay methods utilizing the monoclonal antibodies in the detection of such specific circulating parasite antigens in blood or bodily fluids.
4839288 RETROVIRUS CAPABLE OF CAUSING AIDS, ANTIGENS OBTAINED FROM THIS RETROVIRUS AND CORRESPONDING ANTIBODIES AND THEIR APPLICATION FOR DIAGNOSTIC PURPOSES Luc Montagnier, Denise Guetard, Brim-Vezinet, Francois Clavel, France assigned to Institut Pasteur
Francoise Robinson,
The invention relates to a new variety of retroviruses designated human immunodeficiency virus type II, HIV-II, samples of which have been deposited at CNCM as I-502 and I532. It also concerns purified forms of the antigens which can be obtained from this virus, in particular from the gp 36 and gp 130-140 proteins. These various antigens are useful in medical diagnosis, in particular by being placed in contact with serum of the patient to be dia-