METHOD FOR THERAPEUTICALLY TREATING ABNORMAL CELLS EXPRESSING A MAJOR HISTOCOMPATIBILITY C O M P L E X C L A S S II A N T I G E N USING CYTOLYTIC INDUCER T4 CELLS
DETECTION AND/OR IDENTIFICATION OF MICROORGANISMS IN A TEST SAMPLE USING BIOLUMINESCENCE OR OTHER EXOGENOUS GENETICALLYINTRODUCED MARKER
Shyr-Te Ju assigned to Trustees of Boston University The lbresent invention provides a lymphocytemediated immunotherapy for the treatment of human or animal subjects afflicted with abnormal or tumor cells which express a MHC Class II antigen on their surface. The method utilizes inducer T-cell clones or lines having a demonstrable specificity for an identifiable antigen. These T-cells are activated in-vivo to express cytolytic and therapeutic activity against the abnormal or tumor cells in the subject, 4861595 CELLULAR ENCAPSULATION OF BIOLOGICALS FOR ANIMAL AND HUMAN USE Andrew C Barnes, David L Edwards assigned to Mycogen Corporation
Shimon Y Ulitzur, Jonathan C Kuhn, Haifa, lsrael assigned to Technicon Research A G A method for determining the presence of microorganisms in a tests sample. Exogenous DNA containing a luminescent system or other genetic marker system derived from a suitable donor source is introduced by genetic means into a host microorganism which lacks or poorly expresses the donor DNA and whose presence it is desired to detect. Expression of the donor gene system allows the detection of the host microorganism. Compositions of bacteriophages and plasmids as well as a method for detection of antibiotics in a test sample are described. 4861710 RECOMBINANT DNA CLONE ENCODING LAMININ RECEPTOR Mark E Sobel, Lance A Liotta, Ulla Wewer, Michael C Jayc, William N Drohan assigned to The United States of America as represented by the Department of Health and Human Services
A biological delivery system particularly suited for delivery of protein compounds to animals and humans is disclosed. The system uses a producing microbe itself after suitable treatment by chemical and/or physical means. The product being delivered is contained within the treated microbial cell; it is produced intracellularly by a homologous (native) gene.
The invention provides a recombinant eDNA clone encoding cell surface receptor for laminin, as well as a probe and methods of using that probe to diagnose the aggressiveness of a carcinoma Or the effectiveness of an agent for treating cancer cells.
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RESTRICTION FRAGMENT ANALYSIS OF INDIVIDUALS USING CARDIOVASCULAR SYSTEM PROBES Philippe M Frossard assigned to Biotechnology Research Partners Ltd
GENE CODING FOR THERMOSTABLE BETAGALACTOSIDASE, BACILLUS SUBTILIS HAVING THE GENE, ENZYME CODED BY THE GENE AND A PROCESS FOR THE PRODUCTION THEREOF
Polymorphisms in the renin,' kallikrein, and A N F gene regions are predictive for hypertension in individual human subjects.
Haruhisa Hirata, Hirosuke Okada, Seiji Negoro, Osaka, Japan assigned to Wakamoto Pharmaceutical Co Ltd