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4957599 Alkaline extraction, peroxide bleaching of nonwoody lignocellulosic substrates
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PATENT ABSTRACTS
monoclonal antibodies gives a uniform level of protection against all strains of infectious bursal disease tested. The monoclonal antibodies were effective in inducing priming for an active antiviral response in a heterologous host. 4956479 23-DEOXY-27-CHLORO DERIVATIVES OF LL-F28249 COMPOUNDS Susan Y Tamura, Goro Asato, Hamilton Sq, N J, United Statee assigned to American Cyanamid Company The present invention relates to novel derivatives of LL-F28249 compounds. These LL-F28249 compounds preferably are derived via a controlled microbiological fermentation of Streptomyces cyaneogriseus subspecies noncyanogenus having deposit accession number NRRL 15773. The 23-deoxy-27-halo(chloro) derivatives have the 23-hydroxy group of the LL-F28249 compounds replaced by hydrogen and a halogen such as chlorine in the 27-position with the double bond shifted to the 26,26'position. The novel derivatives of the present invention possess activity as anthelmintic, ectoparasitic, insecticidal, acaricidal and nematicidal agents and are useful in areas of human and animal health and in agricultural crops. Compositions containing the present compounds also are presented herein.
4957599 ALKALINE EXTRACTION, PEROXIDE BLEACHING OF NONWOODY LIGNOCELLULOSIC SUBSTRATES Yu-Chia T Chou, David Garrison, William Lewis assigned to E I du Pont de Nemours and Company An improved process for delignifying and bleaching nonwoody, lignocellulosic material into products digestible by ruminants and ingestible by humans. The process comprises treating the substrate in an alkaline solution for a period of time, separating the wetted substrate from the slurry and then treating the wetted substrate with an alkaline peroxide solution at an initial pH of 8.5 to 11.0 for a period of time, and separating, washing and drying the product.
4957739 PHARMACEUTICAL C O M P O S I T I O N S O F A 105 K D P. HAEMOLYTICA DERIVED ANTIGEN USEFUL FOR TREATMENT OF SHIPPING FEVER Peter Berget, Michael Engler, Sarah Highlander, George Weinstock assigned to Board of Regents The University of Texas System Novel compositions are disclosed for use in the treatment or diagnosis of bovine pasteurellosis, commonly referred to as Shipping Fever. Cellfree Pasteurella haemolytica supernatants are employed to provide individual antigen compositions, identified through reaction with sera from naturally-infected or convalescent cattle. In particular, at least seven individual P. hameolytica antigen groups were recognized in cell-free culture supernatants. Purified P. haemolytica supernatant, formulated in a suitable pharmaceutical vaccine composition is shown to elicit a specific immune response, in both cows and rabbits, directed against the individual immunoreactive P. haemolytica polypeptides identified. Also disclosed are novel recombinant cells, plasmids and bacteriophage which include transcriptionally active P. haemolytica antigen genes. Recombinant clones are similarly selected to be reactive with naturally-infected antisera. Examples, and further disclosure, are also provided which demonstrate the utility of a presently disclosed antibody and antigen compositions in immunodetection of both antigens and antibodies in various biological samples.
4957743 METHOD
FOR TREATING HERPES
Helmu Keller, D 8646 Nordhalben, Federal Republic Of Germany This application relates to a composition and method for treating herpes and chronic inflammatory intestinal tract diseases. According to the invention, herpes, Morbus Crohn and Colitis ulcerosa are treated with a medication prepared from the juice or watery extract of meat-eating plants, preferably the Venus Fly Trap (Dionaea muscipula).
PATENT ABSTRACTS
monoclonal antibodies gives a uniform level of protection against all strains of infectious bursal disease tested. The monoclonal antibodies were effective in inducing priming for an active antiviral response in a heterologous host. 4956479 23-DEOXY-27-CHLORO DERIVATIVES OF LL-F28249 COMPOUNDS Susan Y Tamura, Goro Asato, Hamilton Sq, N J, United Statee assigned to American Cyanamid Company The present invention relates to novel derivatives of LL-F28249 compounds. These LL-F28249 compounds preferably are derived via a controlled microbiological fermentation of Streptomyces cyaneogriseus subspecies noncyanogenus having deposit accession number NRRL 15773. The 23-deoxy-27-halo(chloro) derivatives have the 23-hydroxy group of the LL-F28249 compounds replaced by hydrogen and a halogen such as chlorine in the 27-position with the double bond shifted to the 26,26'position. The novel derivatives of the present invention possess activity as anthelmintic, ectoparasitic, insecticidal, acaricidal and nematicidal agents and are useful in areas of human and animal health and in agricultural crops. Compositions containing the present compounds also are presented herein.
4957599 ALKALINE EXTRACTION, PEROXIDE BLEACHING OF NONWOODY LIGNOCELLULOSIC SUBSTRATES Yu-Chia T Chou, David Garrison, William Lewis assigned to E I du Pont de Nemours and Company An improved process for delignifying and bleaching nonwoody, lignocellulosic material into products digestible by ruminants and ingestible by humans. The process comprises treating the substrate in an alkaline solution for a period of time, separating the wetted substrate from the slurry and then treating the wetted substrate with an alkaline peroxide solution at an initial pH of 8.5 to 11.0 for a period of time, and separating, washing and drying the product.
4957739 PHARMACEUTICAL C O M P O S I T I O N S O F A 105 K D P. HAEMOLYTICA DERIVED ANTIGEN USEFUL FOR TREATMENT OF SHIPPING FEVER Peter Berget, Michael Engler, Sarah Highlander, George Weinstock assigned to Board of Regents The University of Texas System Novel compositions are disclosed for use in the treatment or diagnosis of bovine pasteurellosis, commonly referred to as Shipping Fever. Cellfree Pasteurella haemolytica supernatants are employed to provide individual antigen compositions, identified through reaction with sera from naturally-infected or convalescent cattle. In particular, at least seven individual P. hameolytica antigen groups were recognized in cell-free culture supernatants. Purified P. haemolytica supernatant, formulated in a suitable pharmaceutical vaccine composition is shown to elicit a specific immune response, in both cows and rabbits, directed against the individual immunoreactive P. haemolytica polypeptides identified. Also disclosed are novel recombinant cells, plasmids and bacteriophage which include transcriptionally active P. haemolytica antigen genes. Recombinant clones are similarly selected to be reactive with naturally-infected antisera. Examples, and further disclosure, are also provided which demonstrate the utility of a presently disclosed antibody and antigen compositions in immunodetection of both antigens and antibodies in various biological samples.
4957743 METHOD
FOR TREATING HERPES
Helmu Keller, D 8646 Nordhalben, Federal Republic Of Germany This application relates to a composition and method for treating herpes and chronic inflammatory intestinal tract diseases. According to the invention, herpes, Morbus Crohn and Colitis ulcerosa are treated with a medication prepared from the juice or watery extract of meat-eating plants, preferably the Venus Fly Trap (Dionaea muscipula).