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4959458 Hybrid cell line for producing monoclonal antibody to a human monocyte antigen, antibody, and methods
New Patents
xviii
formula I exhibit activity as platelet activating factor (PAF) antagonists and are, therefore, useful in disease states characterized by excess platelet activating factor or for the prevention and treatment of cardiovascular diseases, pulmonary diseases, immunological disorders, inflammatory diseases, dermatological disorders, shock or transplant rejection.
Hybrid cell line for production of monoclonal antibody to an antigen found on normal human monocytes and granulocytes. The hybrid is formed by fusing splenocytes from immunized BALB/cJ mice with P3X63Ag8UI myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
4959457
ANTI-LYMPHOTOXIN Timothy S Bringman assigned to Genentech Inc Antibody is provided which is capable of neutralizing the in vitro anti-neoplastic cellular activity of lymphotoxin. This antibody, which preferably is produced of monoclonal fusions, can be used in assays for lymphotoxin or for immunoaffinity purification of lymphotoxin.
4959503
DIARYLALKANOIDS HAVING A C T I V I T Y AS L I P O X Y G E N A S E INHIBITORS David T Connor, Daniel L Flynn assigned to Warner-Lambert Company
~59~8
HYBRID CELL LINE FOR PRODUCING MONOCLONAL ANTIBODY TO A HUMAN MONOCYTE ANTIGEN, ANTIBODY, AND METHODS Patrick Kung, Gideon Goldstein assigned to Ortho Pharmaceutical Corporation
The present invention is novel diarylalkanoids having activity as lipoxygenase inhibitors, novel pharmaceutical compositions therefor, and novel methods of use in treating asthma, allergies, cardiovascular diseases, migraines, psoriasis and immunoinflammatorydiseases for diarylalkanoids. The compounds of this invention are also useful as cytoprotective agents.
For information about PATSEARCH ~
Pergamon Orbit InfoLine Inc. 8000 Westpark Drive McLean, VA 22102 USA Telephone (703) 442-0900 Telex: 09-1811
Pergamon Orbit InfoLine Ltd 12 Vandy Street London EC2A 2DE UK Telephone (071) 377-4650 Telex: 8814614
xviii
formula I exhibit activity as platelet activating factor (PAF) antagonists and are, therefore, useful in disease states characterized by excess platelet activating factor or for the prevention and treatment of cardiovascular diseases, pulmonary diseases, immunological disorders, inflammatory diseases, dermatological disorders, shock or transplant rejection.
Hybrid cell line for production of monoclonal antibody to an antigen found on normal human monocytes and granulocytes. The hybrid is formed by fusing splenocytes from immunized BALB/cJ mice with P3X63Ag8UI myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
4959457
ANTI-LYMPHOTOXIN Timothy S Bringman assigned to Genentech Inc Antibody is provided which is capable of neutralizing the in vitro anti-neoplastic cellular activity of lymphotoxin. This antibody, which preferably is produced of monoclonal fusions, can be used in assays for lymphotoxin or for immunoaffinity purification of lymphotoxin.
4959503
DIARYLALKANOIDS HAVING A C T I V I T Y AS L I P O X Y G E N A S E INHIBITORS David T Connor, Daniel L Flynn assigned to Warner-Lambert Company
~59~8
HYBRID CELL LINE FOR PRODUCING MONOCLONAL ANTIBODY TO A HUMAN MONOCYTE ANTIGEN, ANTIBODY, AND METHODS Patrick Kung, Gideon Goldstein assigned to Ortho Pharmaceutical Corporation
The present invention is novel diarylalkanoids having activity as lipoxygenase inhibitors, novel pharmaceutical compositions therefor, and novel methods of use in treating asthma, allergies, cardiovascular diseases, migraines, psoriasis and immunoinflammatorydiseases for diarylalkanoids. The compounds of this invention are also useful as cytoprotective agents.
For information about PATSEARCH ~
Pergamon Orbit InfoLine Inc. 8000 Westpark Drive McLean, VA 22102 USA Telephone (703) 442-0900 Telex: 09-1811
Pergamon Orbit InfoLine Ltd 12 Vandy Street London EC2A 2DE UK Telephone (071) 377-4650 Telex: 8814614