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4996144 Microassay for detection of DNA and RNA
324
PATENT ABSTRACTS
4994578
non-radioactive probes.
CERTAIN ANTI-TUMOR DUOCARMYCIN ANTIBIOTICS FROM STREPTOMYCES Kazunori Ohba, Hiroomi Watabe, Mieko Nagasawa, Shiro Sakakibara, Takashi Shomura, Masaji Sezaki, Shinichi Kondo, Masao Koyama, Tadashi Nakazawa, Haruo Yamamoto, Kanagawa, Japan assigned to Meiji Seika Kaisha Ltd Novel substances exhibiting antimicrobial activity and antitumor activity, a process for producing them by cultivating a microorganism belonging to the genus Streptomyces and capable of producing them and derivatives of such substances.
4994582 NOVEL
ANTIBIOTIC
nucleic
acid
hydridization
4996144 MICROASSAY FOR DETECTION OF DNA AND RNA Anne Crossway, Catherine M Houck assigned to Calgene Inc A novel hybridization diagnostic technique is involved employing micromanipulation of cells for detection of D N A or R N A in the cells. Cellular suspensions are employed, the DNA or RNA purified by microextraction using liquid media having differential solubilization properties, whereby the nucleic acid is retained in an aqueous microdrop. The nucleic acid in the microdrop may then be assayed with a nucleic acid probe in accordance with conventional ways.
NK130119
Takaaki Nishikiori, Masanori Yamazaki, Seiichi Saito, Nobuyoshi Shimada, Takashi Kurokawa, Kiyonobu Hirose, Takumi Yamashita, Takashi Harada, Tokyo, Japan assigned to Nippon Kayaku Kabushiki Kaisha This invention relates to an antibiotic NK130119 of the formula: See Patent for Chemical Structure which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.
4996142 NON-RADIOACTIVE NUCLEIC ACID HYBRIDIZATION PROBES Ali H AI-Hakim, Roger Hull, Norwich, United Kingdom assigned to Agricultural Genetics Company Limited The invention relates to an adduct of a basic macromoleculer and biotin having the general formula: See Patent for Chemical Structure in which MM is the residue of a basic macromolecule formed by substituting the H-atom of one or more primary amino groups; alk represents an optionally substituted alkylene group having from 1 to 10 C-atoms; m is 0 or 1; and n is a positive integer, with the proviso that, where MM represents cytochrome C or histone, m is not 0. The adduct is useful in constructing
4996148 A80407 ANTIBIOTICS Lawrence E Doolin, Richard M Gale, Otis W Godfrey, Robert Hamill, David Maboney, Raymond C Yao assigned to Eli Lilly and Company New glycopeptide antibiotic A80407, comprising A80407A and A80407B, is produced by Kibdelosporangium philippinensis strains N R R L 18198, and N R R L 18199 or AS0407producing mutants of these strains. The A80407 antibiotics have excellent activity against Grampositive bacteria, increase feed-utilization efficiency in monogastric and ruminant animals and improve weight gains in animals.
4996152 AVIAN HERPESVIRUS AMPLICON AS A EUCARYOTIC EXPRESSION VECTOR Jeanne Carter, Robert Silva assigned to The United States of America as represented by the Secretary of Agriculture DNA fragments (seeds) having the characteristics of amplicons, which are useful for amplifying genes of interest, have been isolated
PATENT ABSTRACTS
4994578
non-radioactive probes.
CERTAIN ANTI-TUMOR DUOCARMYCIN ANTIBIOTICS FROM STREPTOMYCES Kazunori Ohba, Hiroomi Watabe, Mieko Nagasawa, Shiro Sakakibara, Takashi Shomura, Masaji Sezaki, Shinichi Kondo, Masao Koyama, Tadashi Nakazawa, Haruo Yamamoto, Kanagawa, Japan assigned to Meiji Seika Kaisha Ltd Novel substances exhibiting antimicrobial activity and antitumor activity, a process for producing them by cultivating a microorganism belonging to the genus Streptomyces and capable of producing them and derivatives of such substances.
4994582 NOVEL
ANTIBIOTIC
nucleic
acid
hydridization
4996144 MICROASSAY FOR DETECTION OF DNA AND RNA Anne Crossway, Catherine M Houck assigned to Calgene Inc A novel hybridization diagnostic technique is involved employing micromanipulation of cells for detection of D N A or R N A in the cells. Cellular suspensions are employed, the DNA or RNA purified by microextraction using liquid media having differential solubilization properties, whereby the nucleic acid is retained in an aqueous microdrop. The nucleic acid in the microdrop may then be assayed with a nucleic acid probe in accordance with conventional ways.
NK130119
Takaaki Nishikiori, Masanori Yamazaki, Seiichi Saito, Nobuyoshi Shimada, Takashi Kurokawa, Kiyonobu Hirose, Takumi Yamashita, Takashi Harada, Tokyo, Japan assigned to Nippon Kayaku Kabushiki Kaisha This invention relates to an antibiotic NK130119 of the formula: See Patent for Chemical Structure which exhibits antifungal, antitumor, vascularizations-inhibitory and insecticidal activities.
4996142 NON-RADIOACTIVE NUCLEIC ACID HYBRIDIZATION PROBES Ali H AI-Hakim, Roger Hull, Norwich, United Kingdom assigned to Agricultural Genetics Company Limited The invention relates to an adduct of a basic macromoleculer and biotin having the general formula: See Patent for Chemical Structure in which MM is the residue of a basic macromolecule formed by substituting the H-atom of one or more primary amino groups; alk represents an optionally substituted alkylene group having from 1 to 10 C-atoms; m is 0 or 1; and n is a positive integer, with the proviso that, where MM represents cytochrome C or histone, m is not 0. The adduct is useful in constructing
4996148 A80407 ANTIBIOTICS Lawrence E Doolin, Richard M Gale, Otis W Godfrey, Robert Hamill, David Maboney, Raymond C Yao assigned to Eli Lilly and Company New glycopeptide antibiotic A80407, comprising A80407A and A80407B, is produced by Kibdelosporangium philippinensis strains N R R L 18198, and N R R L 18199 or AS0407producing mutants of these strains. The A80407 antibiotics have excellent activity against Grampositive bacteria, increase feed-utilization efficiency in monogastric and ruminant animals and improve weight gains in animals.
4996152 AVIAN HERPESVIRUS AMPLICON AS A EUCARYOTIC EXPRESSION VECTOR Jeanne Carter, Robert Silva assigned to The United States of America as represented by the Secretary of Agriculture DNA fragments (seeds) having the characteristics of amplicons, which are useful for amplifying genes of interest, have been isolated