- Email: [email protected]
5099206 Nuclear magnetic resonance spectroscopy
III
New Patents
5998692
5099207
CALCIUM CHELATE AND GADOLINIUM PHARMACEUTICAL COMPOSITION AND METHODS OF X-RAY AND NMR IMAGING
METHOD OF DETERMINING A NUCLEAR MAGNETIZATION DISTRIBUTION OF A SUBVOLUME OF AN OBJECT, METHOD OF SHIMMING A PART OF A STEADY FIELD IN WHICH THE OBJECT IS SITUATED, AND MAGNETIC RESONANCE DEVICE FOR PERFORMING SUCH A METHOD
Heinz Gries, Ulrich Speck, Hanns-Joachim Weinmann, Hans P Niendorf, Wolfgang Seifert, Berlin, Federal Republic Of Germany assigned to Schering Aktiengellschaft Improved metal complex-containing pharmaceutical agents are described which, as an additive, contain one or more complexing agents and/or one or more weak metal complex(es) or mixtures thereof.
5999296 NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Peter R Luyten, Eindhoven, signed to U S Philips Corp
Netherlands
as-
An MRI method for spectroscopy utilizes a sequence which includes four RF electromagnetic pulses (pl, p2, p3, p4), three of which are spatially selective to generate a resonance signal (e) from a sub-volume of an object. The phase difference between the first and the second 90 degrees excitation pulse amounts to 90 degrees. The waiting period (dtl) between the first and the second pulse (p 1, p2) is chosen so that the second pulse (~2) selectively resets the nuclear spins excited by the first non-selective pulse (pl) in the longitudinal direction. The selectively reset magnetization, for example of fat, is recalled, after the dephasing of the nonreset magnetization, for example of water, by the further pulses (~3, ~4). A spectrum is determined from the resonance signal (e). In a modified version in which the phases of the first and the second pulse are the same, the sequence is used for shimming a local field around the subvolume.
Junjiro Imaizumi, Teruaki Fujito, Katsuya Hioka, Tokyo, Japan assigned to Jeol Ltd There is disclosed high-resolution NMR spectroscopy in solids. Magic angle spinning and cross polarization are used in conjunction. The sample is rotated by a spinner at a high speed about an axis oriented at the magic angle 54 degrees44 with respect to the static magnetic field. Under this condition, a 90 degrees pulse is applied to abundant nuclear species, such as 1H that is coupled to dilute nuclear species, such as 13C. Then, a spin-locking pulse or pulse sequence is applied to the abundant nuclear species. An observing pulse or pulse sequence is applied to the dilute nuclear species. The free induction decay signal from the dilute nuclear species is detected. The spin-locking pulse or the observing pulse is amplitude-modulated at a low frequency.
5999208 METHOD FOR MAGNETIC RESONANCE IMAGING AND RELATEDAPPARATUS J M Fitzpatrick, Hsuan Chang assigned to Vanderbilt University An improved method and related apparatus is provided for magnetic resonance imaging with distortions due to magnetic field inhomogeneities and subject susceptibility corrected. The method includes providing a subject positioned within a main magnetic field, a source of RF signals, a receiver for receiving signals em-
New Patents
5998692
5099207
CALCIUM CHELATE AND GADOLINIUM PHARMACEUTICAL COMPOSITION AND METHODS OF X-RAY AND NMR IMAGING
METHOD OF DETERMINING A NUCLEAR MAGNETIZATION DISTRIBUTION OF A SUBVOLUME OF AN OBJECT, METHOD OF SHIMMING A PART OF A STEADY FIELD IN WHICH THE OBJECT IS SITUATED, AND MAGNETIC RESONANCE DEVICE FOR PERFORMING SUCH A METHOD
Heinz Gries, Ulrich Speck, Hanns-Joachim Weinmann, Hans P Niendorf, Wolfgang Seifert, Berlin, Federal Republic Of Germany assigned to Schering Aktiengellschaft Improved metal complex-containing pharmaceutical agents are described which, as an additive, contain one or more complexing agents and/or one or more weak metal complex(es) or mixtures thereof.
5999296 NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Peter R Luyten, Eindhoven, signed to U S Philips Corp
Netherlands
as-
An MRI method for spectroscopy utilizes a sequence which includes four RF electromagnetic pulses (pl, p2, p3, p4), three of which are spatially selective to generate a resonance signal (e) from a sub-volume of an object. The phase difference between the first and the second 90 degrees excitation pulse amounts to 90 degrees. The waiting period (dtl) between the first and the second pulse (p 1, p2) is chosen so that the second pulse (~2) selectively resets the nuclear spins excited by the first non-selective pulse (pl) in the longitudinal direction. The selectively reset magnetization, for example of fat, is recalled, after the dephasing of the nonreset magnetization, for example of water, by the further pulses (~3, ~4). A spectrum is determined from the resonance signal (e). In a modified version in which the phases of the first and the second pulse are the same, the sequence is used for shimming a local field around the subvolume.
Junjiro Imaizumi, Teruaki Fujito, Katsuya Hioka, Tokyo, Japan assigned to Jeol Ltd There is disclosed high-resolution NMR spectroscopy in solids. Magic angle spinning and cross polarization are used in conjunction. The sample is rotated by a spinner at a high speed about an axis oriented at the magic angle 54 degrees44 with respect to the static magnetic field. Under this condition, a 90 degrees pulse is applied to abundant nuclear species, such as 1H that is coupled to dilute nuclear species, such as 13C. Then, a spin-locking pulse or pulse sequence is applied to the abundant nuclear species. An observing pulse or pulse sequence is applied to the dilute nuclear species. The free induction decay signal from the dilute nuclear species is detected. The spin-locking pulse or the observing pulse is amplitude-modulated at a low frequency.
5999208 METHOD FOR MAGNETIC RESONANCE IMAGING AND RELATEDAPPARATUS J M Fitzpatrick, Hsuan Chang assigned to Vanderbilt University An improved method and related apparatus is provided for magnetic resonance imaging with distortions due to magnetic field inhomogeneities and subject susceptibility corrected. The method includes providing a subject positioned within a main magnetic field, a source of RF signals, a receiver for receiving signals em-