- Email: [email protected]
5100646 NMR glomerular filtration test
IV
NewPatents
itted from the subject responsive to the RF pulses and emitting responsive output signals, a computer for receiving the output signals from the receiver and establishing image information related thereto and a visual display for displaying images obtained from the image information. The improved method includes performing a first image generating sequence including generating a 90 degrees RF pulse while simultaneously applying a first slice selection gradient, a phase-encoding gradient and subsequently applying a first preparation gradient after which a 180 degrees refocussing pulse is generated. Subsequently a first read-out gradient is generated while the echo signal is read by the receiver. The sequences is repeated a sufficient number of times to create a first volume image. A second image generating sequence is performed which is similar to the first except that the slice selection gradient, the preparation gradient and the read-out gradient are changed by the same ratio. The second image thereby generated is combined by a computer to create a third, nondistorted image, which may then be delivered to a visual display or other application.
51ooa6 NMR GLOMERULAR FILTRATION TEST Peter L Choyke, Joseph’ A Frank, Howard A Austin assigned to The United States of America as represented by the Secretary of the Department of Health and Human Services A method of determining the glomerular filtration rate of a subject comprises (1) obtaining a serum sample Spre and a urine sample Upre from a subject; (2) administering to the subject an amount of a paramagnetic substance that is filtered by the kidneys and is readily detectable by NMR in serum and urine; (3) allowing for the concentration of the substance to equilibrate between the blood and the extravascular spaces; (4) separating an aliquot of the urine sample VA and obtaining a serum sample from the subject at the time tA; (5) calculating a urine rate (v/a)A from the formula (v/a)A = VA/aA; (6) measuring the magnetic resonance relaxation times of the serum and urine samples, (7) obtaining the concentrations of the paramagnetic substance in the serum samples and the urine samples by comparing their relaxation times to a standard; and (8) calculating GFR from the formula See Patent for Mathematical Equation
5099846 METHOD AND APPARATUS FOR VIDEO PRESENTATION FROM A VARIETY OF SCANNER IMAGING SOURCES Tyrone L Hardy The disclosure is directed to a method and apparatus for presenting a plurality of scanning images in a video presentation. The disclosure is particularly directed to the use of such an apparatus and method in stereotactic surgery, wherein acquisition of a plurality of scanner images, conversion of these images into a selected standard format, storage of the acquired and converted images, selective recall and display of at least two of the images, and independent manipulation of each of the images for comparision are provided. Probe placement can be simulated and the images can be enhanced in various ways. The images used can be, for example, CT, PET, X-ray, DSA, isotope, and NMR scans. Brain map atlas images can be superimposed on and fitted to the scan images of a particular brain. Video displays of three dimensional simulations can also be produced.
5101156 RAPID FLOW MEASUREMENT USING AN NMR IMAGING SYSTEM Norbert J Pelt assigned to General Electric An NMR system measures the velocity of flowing spins in the presence of stationary spins by performing three separate measurement cycles. The first cycle is a reference, the second cycle includes a magnetic field gradient having an incremental, flow sensitizing first moment DeltaMl, and a third measurement cycle includes a magnetic field gradient having an incremental flow sensitizing first moment - DeltaM 1. The resulting NMR signals are processed to produce a velocity measurement.
NewPatents
itted from the subject responsive to the RF pulses and emitting responsive output signals, a computer for receiving the output signals from the receiver and establishing image information related thereto and a visual display for displaying images obtained from the image information. The improved method includes performing a first image generating sequence including generating a 90 degrees RF pulse while simultaneously applying a first slice selection gradient, a phase-encoding gradient and subsequently applying a first preparation gradient after which a 180 degrees refocussing pulse is generated. Subsequently a first read-out gradient is generated while the echo signal is read by the receiver. The sequences is repeated a sufficient number of times to create a first volume image. A second image generating sequence is performed which is similar to the first except that the slice selection gradient, the preparation gradient and the read-out gradient are changed by the same ratio. The second image thereby generated is combined by a computer to create a third, nondistorted image, which may then be delivered to a visual display or other application.
51ooa6 NMR GLOMERULAR FILTRATION TEST Peter L Choyke, Joseph’ A Frank, Howard A Austin assigned to The United States of America as represented by the Secretary of the Department of Health and Human Services A method of determining the glomerular filtration rate of a subject comprises (1) obtaining a serum sample Spre and a urine sample Upre from a subject; (2) administering to the subject an amount of a paramagnetic substance that is filtered by the kidneys and is readily detectable by NMR in serum and urine; (3) allowing for the concentration of the substance to equilibrate between the blood and the extravascular spaces; (4) separating an aliquot of the urine sample VA and obtaining a serum sample from the subject at the time tA; (5) calculating a urine rate (v/a)A from the formula (v/a)A = VA/aA; (6) measuring the magnetic resonance relaxation times of the serum and urine samples, (7) obtaining the concentrations of the paramagnetic substance in the serum samples and the urine samples by comparing their relaxation times to a standard; and (8) calculating GFR from the formula See Patent for Mathematical Equation
5099846 METHOD AND APPARATUS FOR VIDEO PRESENTATION FROM A VARIETY OF SCANNER IMAGING SOURCES Tyrone L Hardy The disclosure is directed to a method and apparatus for presenting a plurality of scanning images in a video presentation. The disclosure is particularly directed to the use of such an apparatus and method in stereotactic surgery, wherein acquisition of a plurality of scanner images, conversion of these images into a selected standard format, storage of the acquired and converted images, selective recall and display of at least two of the images, and independent manipulation of each of the images for comparision are provided. Probe placement can be simulated and the images can be enhanced in various ways. The images used can be, for example, CT, PET, X-ray, DSA, isotope, and NMR scans. Brain map atlas images can be superimposed on and fitted to the scan images of a particular brain. Video displays of three dimensional simulations can also be produced.
5101156 RAPID FLOW MEASUREMENT USING AN NMR IMAGING SYSTEM Norbert J Pelt assigned to General Electric An NMR system measures the velocity of flowing spins in the presence of stationary spins by performing three separate measurement cycles. The first cycle is a reference, the second cycle includes a magnetic field gradient having an incremental, flow sensitizing first moment DeltaMl, and a third measurement cycle includes a magnetic field gradient having an incremental flow sensitizing first moment - DeltaM 1. The resulting NMR signals are processed to produce a velocity measurement.