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5135859 Process for producing polyesters by fermentation; a process for producing optically active carboxylic acids and esters
ii
New Patents
detergent composition which comprises as detergent-active material solely an anionic synthetic detergent, and as builder a water-soluble inorganic or organic builder salt, an improved overall detergency is obtained. The builder salt is typically sodium tripolyphosphate or sodium carbonate, and the lipase is typically obtained from certain Pseudomonas or Chromobacter strains.
5135859 PROCESS FOR PRODUCING P O L Y E S T E R S BY FERMENTATION; A PROCESS FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACIDS AND ESTERS ~ Bernard Witholt, Roland G Lageveen, Eelde, Netherlands assigned to Rijks Universiteit to Grouingen This invention relates to a process for producing polyester biopolymers by culturing Pseudomonas oleovorans bacteria on substrates comprising certain nutrients. The nature of the polyesters can be varied by varying the nature of the carbon source used. In this way polyesters with unsaturated double bonds can be produced, too. From the polyesters, optically active earboxylic acids or esters are produced. The polymers can be used for making articles of manufacture, such as sutures, films, skin and bone grafts.
5151198 METHOD AND APPARATUS FOR SEPARATING FLUIDS USING A CARBONACEOUS POLYMERIC FILTER HAVING A LOI GREATER T H A N 40 Francis P McCullough, Stuart D Stein assigned to The Dow Chemical Company An improvement in an apparatus for separating fluids or non-biotechnological products in solution, wherein said apparatus has a fibrous element which permits flow of fluids therethrough the improvement wherein the fibrous element is composed of non-flammable irreversibly heat set non-graphitic carbonaceous fibers having an LOI greater than 40.
5151265 GAMMA INTERFERON FORMULATION Jiin-Yu Hwang-Felgner, Richard E Jones, James Maher assigned to Genentech Iuc A liquid pharmaceutical composition comprising an effective amount of non-lyophilized gCmma-intefferon. The liquid pharmaceutical composition which additionally includes a buffer capable of maintaining the pH of the liquid composition within the range of 4.0 to 6.0, a stabilizing agent and a non-ionic detergent.
5151268 METHODS OF USING RECOMBINANT HUMAN PROTEIN C Nils U Bang, Robert J Beckmal~n, S Richard Jaskunas, Mei-Huei T Lai, Sheila P Little, George Long, Robert F Santerre assigned to Eft Lilly and Company The present invention comprises novel DNA compounds which encode human protein C activity. A variety of eukaryotic and prokaryotic recombinant DNA expression vectors have been constructed that comprise the novel protein C activity-encoding DNA and drive expression of protein C activity when transformed into an appropriate host cell. The novel expression vectors can be used to produce protein C derivatives, such as non-carboxylated, non-glycosylated, or non-hydroxylated protein C, and to produce protein C precursors, such as nascent or zymogen protein C, and to produce subfragments of protein C, such as active or inactive light and heavy chain. The recombinantproduced protein C activity is useful in the treatment and prevention of a variety of vascular disorders.
5151349 ~METHOD FOR EXPRESSING POLYPEPTIDE HAVING ANTI-
T U M O R AcriVlTY
Shoj Tanaka, Masafumi Tsujimoto, Yayoi Wada, Nobuo Tsuruoka, Hiroshi NakA=~to, Osaka, Japan assigned to Suntory Limited Disclosed is a human TNF derivative with a
New Patents
detergent composition which comprises as detergent-active material solely an anionic synthetic detergent, and as builder a water-soluble inorganic or organic builder salt, an improved overall detergency is obtained. The builder salt is typically sodium tripolyphosphate or sodium carbonate, and the lipase is typically obtained from certain Pseudomonas or Chromobacter strains.
5135859 PROCESS FOR PRODUCING P O L Y E S T E R S BY FERMENTATION; A PROCESS FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACIDS AND ESTERS ~ Bernard Witholt, Roland G Lageveen, Eelde, Netherlands assigned to Rijks Universiteit to Grouingen This invention relates to a process for producing polyester biopolymers by culturing Pseudomonas oleovorans bacteria on substrates comprising certain nutrients. The nature of the polyesters can be varied by varying the nature of the carbon source used. In this way polyesters with unsaturated double bonds can be produced, too. From the polyesters, optically active earboxylic acids or esters are produced. The polymers can be used for making articles of manufacture, such as sutures, films, skin and bone grafts.
5151198 METHOD AND APPARATUS FOR SEPARATING FLUIDS USING A CARBONACEOUS POLYMERIC FILTER HAVING A LOI GREATER T H A N 40 Francis P McCullough, Stuart D Stein assigned to The Dow Chemical Company An improvement in an apparatus for separating fluids or non-biotechnological products in solution, wherein said apparatus has a fibrous element which permits flow of fluids therethrough the improvement wherein the fibrous element is composed of non-flammable irreversibly heat set non-graphitic carbonaceous fibers having an LOI greater than 40.
5151265 GAMMA INTERFERON FORMULATION Jiin-Yu Hwang-Felgner, Richard E Jones, James Maher assigned to Genentech Iuc A liquid pharmaceutical composition comprising an effective amount of non-lyophilized gCmma-intefferon. The liquid pharmaceutical composition which additionally includes a buffer capable of maintaining the pH of the liquid composition within the range of 4.0 to 6.0, a stabilizing agent and a non-ionic detergent.
5151268 METHODS OF USING RECOMBINANT HUMAN PROTEIN C Nils U Bang, Robert J Beckmal~n, S Richard Jaskunas, Mei-Huei T Lai, Sheila P Little, George Long, Robert F Santerre assigned to Eft Lilly and Company The present invention comprises novel DNA compounds which encode human protein C activity. A variety of eukaryotic and prokaryotic recombinant DNA expression vectors have been constructed that comprise the novel protein C activity-encoding DNA and drive expression of protein C activity when transformed into an appropriate host cell. The novel expression vectors can be used to produce protein C derivatives, such as non-carboxylated, non-glycosylated, or non-hydroxylated protein C, and to produce protein C precursors, such as nascent or zymogen protein C, and to produce subfragments of protein C, such as active or inactive light and heavy chain. The recombinantproduced protein C activity is useful in the treatment and prevention of a variety of vascular disorders.
5151349 ~METHOD FOR EXPRESSING POLYPEPTIDE HAVING ANTI-
T U M O R AcriVlTY
Shoj Tanaka, Masafumi Tsujimoto, Yayoi Wada, Nobuo Tsuruoka, Hiroshi NakA=~to, Osaka, Japan assigned to Suntory Limited Disclosed is a human TNF derivative with a