- Email: [email protected]
5155026 Method for determination of nagase and reagent therefor
138
PATENT ABSTRACTS
A method and apparatus for detecting the presence of biological activity in a sample of
material. In the method, a sample of the material is placed in a closed container with a growth medium which includes a carbon source which may be metabolized to produce carbon dioxide. The medium with the sample therein is exposed to conditions conducive to the occurrence of normal metabolic process for a period of time sufficient to cause production of CO2 by the metabolism of the carbon source. Thereafter, the presence of CO2 in the gaseous atmosphere above the medium is detected by measuring the infrared absorbance of the gaseous atmosphere with the container by passing an infrared beam through the container and the gaseous atmosphere and detecting the infrared absorbance of the gaseous atmosphere.
5155025 HYDROGEN PEROXIDE STABILIZATION IN ASSAYS Michael P Allen, Sheng-Fe Li assigned to ChemTrak Hydrogen peroxide stabilized in the presence of blood components by the addition of a metal oxide oxidant, an anionic chelating agent, particularly hydroxylic carboxylate and nitroprusside, and a catalase inhibitor. The composition finds particular application for stabilizing hydrogen peroxide in a diagnostic assay on a bibulous support.
5155026 5155023 ENZYME IMMUNOASSAY PROCEDURE FOR AMPHIPATHIC ANALYTES John Frazer, William B Freese, Michael Voegtline assigned to Synbiotics Corporation Immunoreagents for the release, non-specific capture and detection of lipopolysaccharides (LPS) that may be diagnostic for microorganisms causative for, among other things, Chlamydia trachomatis or Chlamydia psittaci are described.
5155024 BINDER COMPOSITION AND ANALYTICAL ELEMENT HAVING STABILIZED PEROXIDASE IN LAYER CONTAINING THE COMPOSITION Jon N Eikenberry assigned to Eastman Kodak Company An analytical element has a peroxidase-labeled ligand analog distributed within a water-soluble binder composition comprising at least about 50 percent, by weight, of poly(vinyl alcohol). As a result, the peroxidase retains more of its stability prior to use. Such elements can be used to determine any of a number of imrnunologically reactive analytes, such as digoxin.
METHOD FOR DETERMINATION OF NAGASE AND REAGENT THEREFOR Akira Noto, Kunihiro Nakajima, Kazuyuki Sasakura, Tsutomu Sugasawa, Osaka, Japan assigned to Shionogi & Co Ltd Highly sensitive reagent for colorimetrically determining N-acetyl- beta-D-glucosaminidase (NAGase) activity by the continuous method, comprising sodio-3,3'-dichlorophenolsul fonphthaleinyl N-acetyl- beta-D-glucosaminide and a buffer, with which renal dysfunction can be diagnosed precisely, quickly, and easily.
5155032 HORSESHOE CRAB AMEBOCYTE LYSATE FACTOR G ACTIVATION INHIBITOR Shigenor Tanaka, Jun Aketagawa, Makoto Ohki, Shoji Takahashi, Hiroshi Tamura, Yuko Shibata, Tokyo, Japan assigned to Seikagaku Kogyo Co Ltd This invention relates to a horseshoe crab amebocyte lysate factor G activation inhibitor comprising as an active ingredient a polyglycoside containing at least one poly-(l right arrow3)- beta-D-glucoside structure portion consisting of 2 to 370 (1 right arrow3)- beta-Dglucoside structural units of the following formula See Patent for Chemical Structure which are continuously bound to one another. This in-
PATENT ABSTRACTS
A method and apparatus for detecting the presence of biological activity in a sample of
material. In the method, a sample of the material is placed in a closed container with a growth medium which includes a carbon source which may be metabolized to produce carbon dioxide. The medium with the sample therein is exposed to conditions conducive to the occurrence of normal metabolic process for a period of time sufficient to cause production of CO2 by the metabolism of the carbon source. Thereafter, the presence of CO2 in the gaseous atmosphere above the medium is detected by measuring the infrared absorbance of the gaseous atmosphere with the container by passing an infrared beam through the container and the gaseous atmosphere and detecting the infrared absorbance of the gaseous atmosphere.
5155025 HYDROGEN PEROXIDE STABILIZATION IN ASSAYS Michael P Allen, Sheng-Fe Li assigned to ChemTrak Hydrogen peroxide stabilized in the presence of blood components by the addition of a metal oxide oxidant, an anionic chelating agent, particularly hydroxylic carboxylate and nitroprusside, and a catalase inhibitor. The composition finds particular application for stabilizing hydrogen peroxide in a diagnostic assay on a bibulous support.
5155026 5155023 ENZYME IMMUNOASSAY PROCEDURE FOR AMPHIPATHIC ANALYTES John Frazer, William B Freese, Michael Voegtline assigned to Synbiotics Corporation Immunoreagents for the release, non-specific capture and detection of lipopolysaccharides (LPS) that may be diagnostic for microorganisms causative for, among other things, Chlamydia trachomatis or Chlamydia psittaci are described.
5155024 BINDER COMPOSITION AND ANALYTICAL ELEMENT HAVING STABILIZED PEROXIDASE IN LAYER CONTAINING THE COMPOSITION Jon N Eikenberry assigned to Eastman Kodak Company An analytical element has a peroxidase-labeled ligand analog distributed within a water-soluble binder composition comprising at least about 50 percent, by weight, of poly(vinyl alcohol). As a result, the peroxidase retains more of its stability prior to use. Such elements can be used to determine any of a number of imrnunologically reactive analytes, such as digoxin.
METHOD FOR DETERMINATION OF NAGASE AND REAGENT THEREFOR Akira Noto, Kunihiro Nakajima, Kazuyuki Sasakura, Tsutomu Sugasawa, Osaka, Japan assigned to Shionogi & Co Ltd Highly sensitive reagent for colorimetrically determining N-acetyl- beta-D-glucosaminidase (NAGase) activity by the continuous method, comprising sodio-3,3'-dichlorophenolsul fonphthaleinyl N-acetyl- beta-D-glucosaminide and a buffer, with which renal dysfunction can be diagnosed precisely, quickly, and easily.
5155032 HORSESHOE CRAB AMEBOCYTE LYSATE FACTOR G ACTIVATION INHIBITOR Shigenor Tanaka, Jun Aketagawa, Makoto Ohki, Shoji Takahashi, Hiroshi Tamura, Yuko Shibata, Tokyo, Japan assigned to Seikagaku Kogyo Co Ltd This invention relates to a horseshoe crab amebocyte lysate factor G activation inhibitor comprising as an active ingredient a polyglycoside containing at least one poly-(l right arrow3)- beta-D-glucoside structure portion consisting of 2 to 370 (1 right arrow3)- beta-Dglucoside structural units of the following formula See Patent for Chemical Structure which are continuously bound to one another. This in-