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5208536 Method for slice selection in an NMR mas solids imaging system
New Patents
5208324
5208534
PARAMAGNETIC COMPOUNDS
MAGNETIC RESONANCE IMAGING SYSTEM
Jo Klaveness, Pal Rongved, Per Strande, Oslo, Norway assigned to Nycomed Imaging AS There are provided paramagnetic compounds comprising a paramagnetic metal species chelated by a chelating moiety bound by an amide group to a linker group itself bound by an ester group to a macromolecule, wherein said linker group provides a carbon chain of at least 2 atoms between said amide group and said ester group. The novel compounds are particularly suitable as contrast agents, e.g. in magnetic resonance imaging.
5208375 COMPOSITIONS FOR MAGNETIC Dennis A Moore, Rebecca A Wallace assigned to Mallinckrodt Medical Inc Methods and compositions for enhancing magnetic resonance imaging in at least a portion of a warm-blooded animal.
Kazuya Okamoto, Kozo Satoh, Yono, Japan assigned to Kabushiki Kaisha Toshiba A magnetic resonance imaging system includes a magnetic field applying section for applying a static field, gradient field pulses, and an RF field to an object to be examined, a signal detecting section, including a homogeneous coil and a plurality of surface coils arranged to surround a desired region of the object, for detecting magnetic resonance signals from the object through the homogeneous coil and the surface coils, and an image data processing section for obtaining an image of the desired region by synthesizing image data based on the magnetic resonance signals respectively detected by the surface coils upon weighting/adding processing. The system uses differential surface coils as the surface coils. A magnetic resonance signal is detected through the homogeneous coil within the same time interval in which magnetic resonance signals are detected through the surface coils. Weighting functions for weighting/adding processing of image data are determined on the basis of these magnetic resonance signals.
5208533 NMR MACHINE WITH LOW FIELD AND DYNAMIC POLARIZATION Patrick Le Roux, Gif sur Yvette, France assigned to General Electric CGR S A Problems of homogeneity of the resonant field of an NMR machine are solved by differentiating the polarization and resonance functions assigned to coils of the field of said machine. In order to produce a magnetization, use is made of a polarization coil which produces a high field. This polarization field does not need to be homogeneous. Before making measurements, during sequences of excitation-measurement of the electromagnetic wave within the body under examination, the polarization field is switched in order to be cancelled and the body is subjected to a resonance field. This resonance field can be of much lower strength but is on the other hand much more homogeneous. By thus making use of switching of the orienting field, it is shown that the signal-to-noise ratio of the detected signal is maintained.
5208536 METHOD FOR SLICE SELECTION IN AN NMR MAS SOLIDS IMAGING SYSTEM David G Cory assigned to Bruker Instruments Inc A multiple-pulse RF pulse sequence applied in the presence of an oscillating magnetic field gradient enables slice selection in a magic angle spinning nuclear magnetic resonance solids imaging system. Slice selectivity is produced by a series of RF pulses, some of which introduce a nutation that coherently adds for only a selected slice plane of the sample and averages to zero in other areas and some of which average certain gradient-induced modulations so that only those object areas in the selected slice contribute to the output. The pulse train is applied in a manner synchronous with rotor rotation so that rotation induced modulations average to zero over one or more rotor rotation periods.
5208324
5208534
PARAMAGNETIC COMPOUNDS
MAGNETIC RESONANCE IMAGING SYSTEM
Jo Klaveness, Pal Rongved, Per Strande, Oslo, Norway assigned to Nycomed Imaging AS There are provided paramagnetic compounds comprising a paramagnetic metal species chelated by a chelating moiety bound by an amide group to a linker group itself bound by an ester group to a macromolecule, wherein said linker group provides a carbon chain of at least 2 atoms between said amide group and said ester group. The novel compounds are particularly suitable as contrast agents, e.g. in magnetic resonance imaging.
5208375 COMPOSITIONS FOR MAGNETIC Dennis A Moore, Rebecca A Wallace assigned to Mallinckrodt Medical Inc Methods and compositions for enhancing magnetic resonance imaging in at least a portion of a warm-blooded animal.
Kazuya Okamoto, Kozo Satoh, Yono, Japan assigned to Kabushiki Kaisha Toshiba A magnetic resonance imaging system includes a magnetic field applying section for applying a static field, gradient field pulses, and an RF field to an object to be examined, a signal detecting section, including a homogeneous coil and a plurality of surface coils arranged to surround a desired region of the object, for detecting magnetic resonance signals from the object through the homogeneous coil and the surface coils, and an image data processing section for obtaining an image of the desired region by synthesizing image data based on the magnetic resonance signals respectively detected by the surface coils upon weighting/adding processing. The system uses differential surface coils as the surface coils. A magnetic resonance signal is detected through the homogeneous coil within the same time interval in which magnetic resonance signals are detected through the surface coils. Weighting functions for weighting/adding processing of image data are determined on the basis of these magnetic resonance signals.
5208533 NMR MACHINE WITH LOW FIELD AND DYNAMIC POLARIZATION Patrick Le Roux, Gif sur Yvette, France assigned to General Electric CGR S A Problems of homogeneity of the resonant field of an NMR machine are solved by differentiating the polarization and resonance functions assigned to coils of the field of said machine. In order to produce a magnetization, use is made of a polarization coil which produces a high field. This polarization field does not need to be homogeneous. Before making measurements, during sequences of excitation-measurement of the electromagnetic wave within the body under examination, the polarization field is switched in order to be cancelled and the body is subjected to a resonance field. This resonance field can be of much lower strength but is on the other hand much more homogeneous. By thus making use of switching of the orienting field, it is shown that the signal-to-noise ratio of the detected signal is maintained.
5208536 METHOD FOR SLICE SELECTION IN AN NMR MAS SOLIDS IMAGING SYSTEM David G Cory assigned to Bruker Instruments Inc A multiple-pulse RF pulse sequence applied in the presence of an oscillating magnetic field gradient enables slice selection in a magic angle spinning nuclear magnetic resonance solids imaging system. Slice selectivity is produced by a series of RF pulses, some of which introduce a nutation that coherently adds for only a selected slice plane of the sample and averages to zero in other areas and some of which average certain gradient-induced modulations so that only those object areas in the selected slice contribute to the output. The pulse train is applied in a manner synchronous with rotor rotation so that rotation induced modulations average to zero over one or more rotor rotation periods.