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5234817 Wash solution containing a cationic surfactant and its use in chlamydial and gonococcal determinations
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Pergamon
Comp. lmmun, Microbiol. Infect. Dis. Vol. 17, No. I, pp. Ill VII, 1994 Elsevier Science Ltd. Printed in Great Britain 0147-9571/94 $6.00 + 0.00
NEW PATENTS This section contains abstracts and, where appropriate, illustrations of recently issued United States patents and published patent application filed from over 30 countries under the Patent Cooperation Treaty. This information was obtained from recent additions to the PATSEARCH" online database in accordance with interest profiles developed by the Editors. Further information about online patent searching can be obtained from Research on Demand, Inc., 2421 Fourth Street, Ste. C., Berkeley, CA 94710, U.S.A. [Tel. 510-841 1145: Fax 510-841 6311].
5234683 METHOD OF STIMULATING IMMUNE SYSTEM
A wash solution having a pH of from about 7 to about 12 comprises at least about 0.1 weight percent of one or more cationic surfactants. This wash solution is useful in assays for chlamydial or gonococcal organisms, such as Chlamydia trachomatis or Neisseria gonorrhoeae. In particular, it can be used to remove uncomplexed materials from the insolubilized complexes formed between antigen and antibodies.
THE
Robert L Hunter, William L Ragland assigned to Emory University The present invention relates to biologicallyactive copolymers and to compounds that can be safely used to cause the thymus of an animal or human to increase in size, thereby replenishing the T-lymphocyte population. When injected into an animal or human with an antigen, certain of the biologically-active copolymers cause immunosuppression to the antigen. When injected into poultry, certain of the biologicallyactive copolymers modulate immune responsiveness. The biologically active copolymers are also useful as growth promoters for animals. Compounds within the biologicallyactive copolymers of the present invention are effective tumoricidal agents. At low concentration, certain of the biologically-active copolymers can cause dedifferentiated cells to differentiate. The biologically-active copolymer of the present invention is a safe and non-toxic formulation that can effectively be administered to animals or humans. The biologically-active copolymer can be mixed in an oil and water emulsion and administered to an animal or human by injection or by oral administration.
5235042 ENDOTHELIAL CELL GROWTH FACTOR Michae Klagsbrun assigned to The Children's Medical Center Corporation Endothelial cell growth factor (ECG) from various sources possesses a strong and specific affinity for heparin. This strong affinity of ECG for heparin enables removal of undesired impurities from a mixture comprising ECG by: a) contacting immobilized heparin with the mixture to form a heparin-ECG complex; b) separating uncomplexed mixture from the complex; and c) contacting the complex with a salt solution of a salt concentration and pH effective to separate the ECG from the heparin. The resulting purified ECG (or fragment thereof) is useful in therapeutics and as an additive for cell culturing. The purified ECG is also useful to raise antibodies that are used in therapeutics and in ECG immunoassays.
5234817 5236708
WASH SOLUTION CONTAINING A CATIONIC SURFACTANT AND ITS USE IN CHLAMYDIAL AND GONOCOCCAL DETERMINATIONS
REDUCED-PROTEIN SUBUNIT VACCINE FOR SWINE DYSENTERY Anthony Ostle, Michael J Wannemuehler assigned to Iowa State University Research Foundation Inc; Ambico lnc
Allan Pronovost, James H Gilbert assigned to Eastman Kodak Company Ill
Pergamon
Comp. lmmun, Microbiol. Infect. Dis. Vol. 17, No. I, pp. Ill VII, 1994 Elsevier Science Ltd. Printed in Great Britain 0147-9571/94 $6.00 + 0.00
NEW PATENTS This section contains abstracts and, where appropriate, illustrations of recently issued United States patents and published patent application filed from over 30 countries under the Patent Cooperation Treaty. This information was obtained from recent additions to the PATSEARCH" online database in accordance with interest profiles developed by the Editors. Further information about online patent searching can be obtained from Research on Demand, Inc., 2421 Fourth Street, Ste. C., Berkeley, CA 94710, U.S.A. [Tel. 510-841 1145: Fax 510-841 6311].
5234683 METHOD OF STIMULATING IMMUNE SYSTEM
A wash solution having a pH of from about 7 to about 12 comprises at least about 0.1 weight percent of one or more cationic surfactants. This wash solution is useful in assays for chlamydial or gonococcal organisms, such as Chlamydia trachomatis or Neisseria gonorrhoeae. In particular, it can be used to remove uncomplexed materials from the insolubilized complexes formed between antigen and antibodies.
THE
Robert L Hunter, William L Ragland assigned to Emory University The present invention relates to biologicallyactive copolymers and to compounds that can be safely used to cause the thymus of an animal or human to increase in size, thereby replenishing the T-lymphocyte population. When injected into an animal or human with an antigen, certain of the biologically-active copolymers cause immunosuppression to the antigen. When injected into poultry, certain of the biologicallyactive copolymers modulate immune responsiveness. The biologically active copolymers are also useful as growth promoters for animals. Compounds within the biologicallyactive copolymers of the present invention are effective tumoricidal agents. At low concentration, certain of the biologically-active copolymers can cause dedifferentiated cells to differentiate. The biologically-active copolymer of the present invention is a safe and non-toxic formulation that can effectively be administered to animals or humans. The biologically-active copolymer can be mixed in an oil and water emulsion and administered to an animal or human by injection or by oral administration.
5235042 ENDOTHELIAL CELL GROWTH FACTOR Michae Klagsbrun assigned to The Children's Medical Center Corporation Endothelial cell growth factor (ECG) from various sources possesses a strong and specific affinity for heparin. This strong affinity of ECG for heparin enables removal of undesired impurities from a mixture comprising ECG by: a) contacting immobilized heparin with the mixture to form a heparin-ECG complex; b) separating uncomplexed mixture from the complex; and c) contacting the complex with a salt solution of a salt concentration and pH effective to separate the ECG from the heparin. The resulting purified ECG (or fragment thereof) is useful in therapeutics and as an additive for cell culturing. The purified ECG is also useful to raise antibodies that are used in therapeutics and in ECG immunoassays.
5234817 5236708
WASH SOLUTION CONTAINING A CATIONIC SURFACTANT AND ITS USE IN CHLAMYDIAL AND GONOCOCCAL DETERMINATIONS
REDUCED-PROTEIN SUBUNIT VACCINE FOR SWINE DYSENTERY Anthony Ostle, Michael J Wannemuehler assigned to Iowa State University Research Foundation Inc; Ambico lnc
Allan Pronovost, James H Gilbert assigned to Eastman Kodak Company Ill