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5278183 Method for the treatment of autoimmune diseases
IX
New Patents antibodies to the virus, and the use of polynucleotide probes to detect the viral genome. Vaccines include both wholly and partially inactivated viruses inactivated cell lines expressing FIV antigens, and subunit vaccines. Whole, live virus is also useful as a model system for predicting the behavior of human immunodeficiency virus (HIV).
The addition of 5-androstene 3 beta, 17 betadiol and/or 5-androstene 3 beta,7 beta, 17 beta trio1 to growth media increases proliferation of lymphocytes in culture. By methods of the invention it is possible to increase production of autogenous lymphocytes for administration to the patient.
5278183 5275934 METHOD OF DETECTING VIRAL INFECTION IN VACCINATED ANIMALS Leonard E Post, Darrell R Thomsen assigned to The Upjohn Company Provided are methods for determining whether a vaccinated animal is uninfected or infected with a virulent wild-type virus. Methods, vaccines and viruses are disclosed that are useful to seratologically distinguish infected from uninfected animals in populations of animals vaccinated with a properly incapacitated virus lacking an antigen of the wild-type virus.
METHOD FOR THE TREATMENT OF AUTOIMMUNE DISEASES Bruno Silvestrini, Rome, Italy assigned to Instituto Ricerca Francesco Angelini S p A A pharmaceutical composition for the treatment of autoimmune diseases comprising an effective amount of a compound of formula See Patent for Tabular Presentation PS where A is the nucleus of I-benzyl-indazol-3-yl, R and R’, the same or different from each other, are H or an alkyl having from I to 5 carbon atoms, R”’ is H or an alkyl having from I to 4 carbon atoms, or, when R”’ is H, of a salt thereof with organic or inorganic pharmaceutically acceptable bases.
5279965
5277904
RECOMBINANT INFECTIOUS LARYNGOTRACHEITIS VIRUS
BROAD SPECTRUM DERMATOPHYTE VACCINE
Calvin L Keeler
Allan C Pier A vaccine for the prophylaxis of dermatophyte infection in animals, such as guinea pigs, cats, rabbits, horses and lambs comprising a suspension of killed T. equinum, T. mentagrophytes (var. granulare), M. canis and M. gypseum in an effective amount combined with an adjuvant. The vaccine of the invention contains advantages over prior art dermatophyte vaccines in that it reduces the risk of infection in inoculated animals and persons utilizing the vaccine and provides cross-immunity.
The present invention is concerned with the preparation of an Infectious Laryngotracheitis Virus (ILTV) mutant which does not produce a functional thymidine kinase enzyme as a result of a mutation in the TK gene, and its preparation. The invention also relates to an ILTV mutant containing a heterologous gene encoding an antigen of an avian pathogen incorporated into the TK gene. Such an ILTV mutant can be applied as a vector vaccine to induce an immune response after infection of an appropriate host animal.
5277907
5281416
REGULATION OF THE IMMUNE SYSTEM Roger M Loria assigned monwealth University
to Virginia
Com-
SWINE DYSENTERY
VACCINE
Peter Coloe, East Doncaster, Australia assigned to Royal Melbourne Institute of Technology Limited
New Patents antibodies to the virus, and the use of polynucleotide probes to detect the viral genome. Vaccines include both wholly and partially inactivated viruses inactivated cell lines expressing FIV antigens, and subunit vaccines. Whole, live virus is also useful as a model system for predicting the behavior of human immunodeficiency virus (HIV).
The addition of 5-androstene 3 beta, 17 betadiol and/or 5-androstene 3 beta,7 beta, 17 beta trio1 to growth media increases proliferation of lymphocytes in culture. By methods of the invention it is possible to increase production of autogenous lymphocytes for administration to the patient.
5278183 5275934 METHOD OF DETECTING VIRAL INFECTION IN VACCINATED ANIMALS Leonard E Post, Darrell R Thomsen assigned to The Upjohn Company Provided are methods for determining whether a vaccinated animal is uninfected or infected with a virulent wild-type virus. Methods, vaccines and viruses are disclosed that are useful to seratologically distinguish infected from uninfected animals in populations of animals vaccinated with a properly incapacitated virus lacking an antigen of the wild-type virus.
METHOD FOR THE TREATMENT OF AUTOIMMUNE DISEASES Bruno Silvestrini, Rome, Italy assigned to Instituto Ricerca Francesco Angelini S p A A pharmaceutical composition for the treatment of autoimmune diseases comprising an effective amount of a compound of formula See Patent for Tabular Presentation PS where A is the nucleus of I-benzyl-indazol-3-yl, R and R’, the same or different from each other, are H or an alkyl having from I to 5 carbon atoms, R”’ is H or an alkyl having from I to 4 carbon atoms, or, when R”’ is H, of a salt thereof with organic or inorganic pharmaceutically acceptable bases.
5279965
5277904
RECOMBINANT INFECTIOUS LARYNGOTRACHEITIS VIRUS
BROAD SPECTRUM DERMATOPHYTE VACCINE
Calvin L Keeler
Allan C Pier A vaccine for the prophylaxis of dermatophyte infection in animals, such as guinea pigs, cats, rabbits, horses and lambs comprising a suspension of killed T. equinum, T. mentagrophytes (var. granulare), M. canis and M. gypseum in an effective amount combined with an adjuvant. The vaccine of the invention contains advantages over prior art dermatophyte vaccines in that it reduces the risk of infection in inoculated animals and persons utilizing the vaccine and provides cross-immunity.
The present invention is concerned with the preparation of an Infectious Laryngotracheitis Virus (ILTV) mutant which does not produce a functional thymidine kinase enzyme as a result of a mutation in the TK gene, and its preparation. The invention also relates to an ILTV mutant containing a heterologous gene encoding an antigen of an avian pathogen incorporated into the TK gene. Such an ILTV mutant can be applied as a vector vaccine to induce an immune response after infection of an appropriate host animal.
5277907
5281416
REGULATION OF THE IMMUNE SYSTEM Roger M Loria assigned monwealth University
to Virginia
Com-
SWINE DYSENTERY
VACCINE
Peter Coloe, East Doncaster, Australia assigned to Royal Melbourne Institute of Technology Limited