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5384022 Method and apparatus for electrophoretic DNA band isolation
780
PATENT ABSTRACTS
5382525
5384022
METHOD OF EFFECTING INCREASED PERFORMANCE OF DIAGNOSTIC ENZYME REACTION SYSTEMS USING NOBLE GASES
METHOD AND APPARATUS FOR ELECTROPHORETIC DNA BAND ISOLATION
Spencer Kevin Hinsdale, IL, UNITED STATES Assigned to American Air Liquide A method of effeoting increased performance of diagnostic enzyme reaction systems which includes contacting at least one reagent of an enzyme-diagnostic kit during use of the reagent in conjuction with the kit with a noble gas, mixture of noble gases or gas mixtures containing at least one noble gas.
5382655 PROCESS FOR THE PURIFICATION OF CYCLOSPORIN A Szanya Tibor; Hanak Laszio; Strbka Gyongyi; Nagy Edit; Melczer Istvan; Deak Gyorgy; MakoBerta; Karczub Anita; Balint Janos; Radnai Ferenc; Karacxony Erno Hajdufi Csaba; Keri Viimos; Marton Gyula; Dencs Judit; Kelemen Janos Veszpr HUNGARY Assigned to Biogal Gyogyszerarugyar RT A process is disclosed for the solution chromatographic purification of cyclosporin A from a starting mixture containing one or more of cyclosporin A, B, C, other cyclosporin components that are more polar or more apolar than cyclosporin A, and other like contaminants, by heating the starting mixture or an evaporation residue thereof to a temperature from about g0 degrees C. to about 115 degrees C., melting the heated starting mixture, and carrying out solution chromatography of the melted material, suitably first in a 48:50:2 mixture of chloroform, dichloromethane, and ethanol, and then in a mixture of like proportions, of the solvents chloroform, ethylacetate, and ethanol.
Rajasekaran Ayyappan K New York, NY, UNITED STATES Assigned to Cornell Research Foundation Ine An electrophoresis system is used to segregate a molecular specimen, the apparatus comprising a container, a gel layer and a buffer solution resident in the container, the gel layer having a well for receiving the molecular specimen. Electrical contacts are resident in the container and apply a potential across the gel layer to enable migration of the molecular specimen along a migration path in the gel layer. A second well is positioned in the gel layer and downstream in the migration path. A cup is inserted into the second well, the cup having a rim which,when the cup is resident in the second well, is positioned below the migration path of the molecular specimen within the gel layer. A membrane is also placeable in the second well to prevent migration of the molecular specimen past the cup. The molecular specimen thereby migrates into the cup and is prevented by the membrane from further migration along the migration path. Aspiration of the contents of the cup enables recovery of the molecular specimen.
5384239 METHOD FOR ANALYZING THE GLYCATION OF HEMOGLOBIN Saundexs Alexande San Carlos, CA, UNITED STATES Assigned to Chronomed Inc As red blood cells age, their hemoglobin is progressively glycosylated. This invention relates to analyzing the history of blood sugar metabolism over a period of several months by taking a blood sample, separating the cells into age-ordered cohorts, determining glycohemoglobin levels in the cells of each cohort, and correlating glycohemoglobin levels with red blood cell age, while correcting for the reversibility of the Amadori rearrangemem.
PATENT ABSTRACTS
5382525
5384022
METHOD OF EFFECTING INCREASED PERFORMANCE OF DIAGNOSTIC ENZYME REACTION SYSTEMS USING NOBLE GASES
METHOD AND APPARATUS FOR ELECTROPHORETIC DNA BAND ISOLATION
Spencer Kevin Hinsdale, IL, UNITED STATES Assigned to American Air Liquide A method of effeoting increased performance of diagnostic enzyme reaction systems which includes contacting at least one reagent of an enzyme-diagnostic kit during use of the reagent in conjuction with the kit with a noble gas, mixture of noble gases or gas mixtures containing at least one noble gas.
5382655 PROCESS FOR THE PURIFICATION OF CYCLOSPORIN A Szanya Tibor; Hanak Laszio; Strbka Gyongyi; Nagy Edit; Melczer Istvan; Deak Gyorgy; MakoBerta; Karczub Anita; Balint Janos; Radnai Ferenc; Karacxony Erno Hajdufi Csaba; Keri Viimos; Marton Gyula; Dencs Judit; Kelemen Janos Veszpr HUNGARY Assigned to Biogal Gyogyszerarugyar RT A process is disclosed for the solution chromatographic purification of cyclosporin A from a starting mixture containing one or more of cyclosporin A, B, C, other cyclosporin components that are more polar or more apolar than cyclosporin A, and other like contaminants, by heating the starting mixture or an evaporation residue thereof to a temperature from about g0 degrees C. to about 115 degrees C., melting the heated starting mixture, and carrying out solution chromatography of the melted material, suitably first in a 48:50:2 mixture of chloroform, dichloromethane, and ethanol, and then in a mixture of like proportions, of the solvents chloroform, ethylacetate, and ethanol.
Rajasekaran Ayyappan K New York, NY, UNITED STATES Assigned to Cornell Research Foundation Ine An electrophoresis system is used to segregate a molecular specimen, the apparatus comprising a container, a gel layer and a buffer solution resident in the container, the gel layer having a well for receiving the molecular specimen. Electrical contacts are resident in the container and apply a potential across the gel layer to enable migration of the molecular specimen along a migration path in the gel layer. A second well is positioned in the gel layer and downstream in the migration path. A cup is inserted into the second well, the cup having a rim which,when the cup is resident in the second well, is positioned below the migration path of the molecular specimen within the gel layer. A membrane is also placeable in the second well to prevent migration of the molecular specimen past the cup. The molecular specimen thereby migrates into the cup and is prevented by the membrane from further migration along the migration path. Aspiration of the contents of the cup enables recovery of the molecular specimen.
5384239 METHOD FOR ANALYZING THE GLYCATION OF HEMOGLOBIN Saundexs Alexande San Carlos, CA, UNITED STATES Assigned to Chronomed Inc As red blood cells age, their hemoglobin is progressively glycosylated. This invention relates to analyzing the history of blood sugar metabolism over a period of several months by taking a blood sample, separating the cells into age-ordered cohorts, determining glycohemoglobin levels in the cells of each cohort, and correlating glycohemoglobin levels with red blood cell age, while correcting for the reversibility of the Amadori rearrangemem.