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5426108 Antibiotic 31F508 alpha1, alpha2, beta1 and beta2
374
PATENT ABSTRACTS
A novel human protein, minactivin, can be produced by recombinant DNA technology, Biologically active native minactivin, peptides derived from minactivin, and their amino acid sequences can also he purified.
5426045 METHOD FOR CULTURING MAMMALIAN CELLS IN A MEDIUM CONTAINING FISH
SERUM Sawyer Evelyn; Sawyer Philip Kennebunkport, ME, UNITED STATES Assigned to Sea Run Holdings Inc
5426108 ANTIBIOTIC 31F508 ALPHA1, ALPHA2, BETA1 AND BETA2 Zaccardi Joseph New Windsor, NY, UNITED STATES Assigned to American Cyanamid Company This invention relates to antibiotic 31F508 alphal of the formula (*See Patent for Chemical Structure*) 31F508 alpha2, 31F508 betal and 31F508 beta2, derived from the microorganism Streptomyces viridodiastaticus subsp, littus which are useful as anti-bacterial agents.
5427782 A method for culturing mammalian cells using fish serum. The method uses serum extracted from the blood of fishes to culture mammalian cells for various purposes. The technique has the key advantages of 1) freedom from mammalian infectious agents that could contaminate cell lines or endanger researchers or recipients of therapeutants derived from mammalian cell culture; 2) consistent and reproducible serum content and quality; 3) low cross-reactivity; and 4) the appropriate serum nutrients to maintain the growth of mammalian cells. Fish serum is used together with designated defined media to allow mammalian ceils to grow and populations of these cells to he maintained. Blood serum is derived from captive stocks of fish raised under controlled conditions such that the diet, habitat, genetics, life history, and reproductive status of the fish remains substantially consistent and reproducible.
INTRANASAL IMMUNIZATION AGAINST VIRAL INFECTION USING VIRAL GLYCOPROTEIN SUBUNIT VACCINE Compans Richard; Ray Ranjit UNITED STATES Assigned Engineering Associates Inc
Helena, AL, to Molecular
Method for immunizing against respiratory vital infection by administering intranasally an immunogenically effective amount of a vital envelope subunit vaccine, preferably comprising a mixture of the vital envelope glycoproteins complexed with a lipid. 5427783
5426046 HUMAN MONOCLONAL ANTIBODY TO LIPID A OF GRAM NEGATIVE BACTERIA Kaplan Henry; Braude Abraham 1; Teng Nelson N H Stanford, CA, UNITED STATES Assigned to The Board of Trustees of the Leland Stanford Junior University A human monoclonal antibody, C5, specific for lipid A of the endotoxin core of Gram-negative bacteria and the hybridoma cell line which produces the antibody. The monoclonal antibody is produced by the fusion of lipid A sensitized lymphocytes and an appropriate fusion partner.
ZEAXANTHIN-CONTAINING COMPOSITIONS PRODUCED FLAVOBACTER1UM MULTIVORUM
BY
Gierhart Dennis High Ridge, MO, UNITED STATES Assigned to Applied Food Biotechnology Inc Zeaxanthin is produced using Flavobacterium multivorum. The process and the nutrient medium used in the process provide greater zeaxanthin and cell yields per liter, at a lower cost, and more rapidly than known methods and microorganisms. Biomass compositions containing the microorganism of this invention are also disclosed.
PATENT ABSTRACTS
A novel human protein, minactivin, can be produced by recombinant DNA technology, Biologically active native minactivin, peptides derived from minactivin, and their amino acid sequences can also he purified.
5426045 METHOD FOR CULTURING MAMMALIAN CELLS IN A MEDIUM CONTAINING FISH
SERUM Sawyer Evelyn; Sawyer Philip Kennebunkport, ME, UNITED STATES Assigned to Sea Run Holdings Inc
5426108 ANTIBIOTIC 31F508 ALPHA1, ALPHA2, BETA1 AND BETA2 Zaccardi Joseph New Windsor, NY, UNITED STATES Assigned to American Cyanamid Company This invention relates to antibiotic 31F508 alphal of the formula (*See Patent for Chemical Structure*) 31F508 alpha2, 31F508 betal and 31F508 beta2, derived from the microorganism Streptomyces viridodiastaticus subsp, littus which are useful as anti-bacterial agents.
5427782 A method for culturing mammalian cells using fish serum. The method uses serum extracted from the blood of fishes to culture mammalian cells for various purposes. The technique has the key advantages of 1) freedom from mammalian infectious agents that could contaminate cell lines or endanger researchers or recipients of therapeutants derived from mammalian cell culture; 2) consistent and reproducible serum content and quality; 3) low cross-reactivity; and 4) the appropriate serum nutrients to maintain the growth of mammalian cells. Fish serum is used together with designated defined media to allow mammalian ceils to grow and populations of these cells to he maintained. Blood serum is derived from captive stocks of fish raised under controlled conditions such that the diet, habitat, genetics, life history, and reproductive status of the fish remains substantially consistent and reproducible.
INTRANASAL IMMUNIZATION AGAINST VIRAL INFECTION USING VIRAL GLYCOPROTEIN SUBUNIT VACCINE Compans Richard; Ray Ranjit UNITED STATES Assigned Engineering Associates Inc
Helena, AL, to Molecular
Method for immunizing against respiratory vital infection by administering intranasally an immunogenically effective amount of a vital envelope subunit vaccine, preferably comprising a mixture of the vital envelope glycoproteins complexed with a lipid. 5427783
5426046 HUMAN MONOCLONAL ANTIBODY TO LIPID A OF GRAM NEGATIVE BACTERIA Kaplan Henry; Braude Abraham 1; Teng Nelson N H Stanford, CA, UNITED STATES Assigned to The Board of Trustees of the Leland Stanford Junior University A human monoclonal antibody, C5, specific for lipid A of the endotoxin core of Gram-negative bacteria and the hybridoma cell line which produces the antibody. The monoclonal antibody is produced by the fusion of lipid A sensitized lymphocytes and an appropriate fusion partner.
ZEAXANTHIN-CONTAINING COMPOSITIONS PRODUCED FLAVOBACTER1UM MULTIVORUM
BY
Gierhart Dennis High Ridge, MO, UNITED STATES Assigned to Applied Food Biotechnology Inc Zeaxanthin is produced using Flavobacterium multivorum. The process and the nutrient medium used in the process provide greater zeaxanthin and cell yields per liter, at a lower cost, and more rapidly than known methods and microorganisms. Biomass compositions containing the microorganism of this invention are also disclosed.