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PATENT ABSTRACTS
5434340 TRANSGENIC
5435730
MICE DEPLETED
IN MATURE T-CELLS AND METHODS FOR MAKING TRANSGENIC
MICE
Krimpenfort Paulus J; Betas Antonius J M Amsterdam, NETHERLANDS assigned to GenPharm International Inc Transgenic mice having a phenotype characterized by the substantial absence of mature T lymphocytes otherwise naturally occurring in said mice. The phenotype is conferred in the transgenic mouse by a transgene contained in at least the precursor stem cell of the T lymphocyte which is depleted. The transgene comprises a DNA sequence encoding a T cell receptor polypeptide variant which inhibits maturation of the T lymphocyte.
GAL OPERON
OF
STREPTOMYCES Adams Craig W; Brawner Mary E; Fomwald James; Schmidt Francis J King of Prussia, PA, UNITED STATES A recombinant DNA molecule comprising the Streptomyces gal operon galK gene; galE gene; gaiT gene; P1 promoter; P2 promoter; P2 promoter expression unit; P1 promoter regulated region; or the entire Streptomyces gal operon.
5436000 FLAGELLA-LESS
5434344 SUCROSE ACCUMULATING TOMATO
TECHNOLOGY
Bennett Alan B; Yelle Serg Davis, CA, UNITED STATES assigned to The Regents of the University of California A new tomato cultivar is provided which is homozygous for a genetically fixable recessive genetic factor which confers the ability to bear fruit that accumulate sucrose. The increased sucrose content, in turn, leads to a higher total soluble solids content in the mature fruit. Higher total soluble solids in tomato fruit are of particular importance to the tomato processing industry. A method for producing the claimed cultivar is also provided. The claimed genetic factor can be derived from any Lycopersicon species which accumulates sucrose in the mature fruit. Once genetically fixed in a tomato cultivar, the factor can be transmitted to other plants in a predictable manner.
BORRELIA
Barbour Alan; Bundoc Virgili San Antonio, TX, UNITED STATES assigned to University of Texas System This invention relates to flagella-less strains of Borrelia and to novel methods for use of the microorganisms as vaccines and in diagnostic assays. Although a preferred embodiment of the invention is directed to Borrelia burgdorferi, the present invention encompasses flagella-less strains of other microorganisms belonging to the genus Borrelia. Accordingly, with the aid of the disclosure, flagella-less mutants of other Borrelia species, e.g., B. coriacei, which causes epidemic bovine abortion, B. anserina, which causes avian spirochetosis, and B. recurrentis and other Borrelia species causative of relapsing fever, such as Borrelia hermsii, Borrelia turicatae, Borrelia duttoni, Borrelia persiea, and Borrelia hispanica, can be prepared and used in accordance with the present invention and are within the scope of the invention. Therefore, a preferred embodiment comprises a composition of matter comprising a substantially pure preparation of a strain of a flagella-less microorganism belonging to the genus Borrelia.