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5468639 Isolated DNA molecule encoding shet2 of Shigella flexneri 2a
PATENTABSTRACTS
proteins, and antibodies bind the ax1 receptor.
which specifically
75
2a vaccine candidate. 5468845
5468636
ANTIBODIES
TO OSTEOGENIC PROTEINS
BACILLUS THURINGIENSIS FOR CONTROLLING PESTS IN THE FAMILY
APHIDIDAE
Payne Jewel M; Cannon Raymond J; Schnepf H Ernest; Schwab George E San Diego, CA, UNITED STATES assigned to Mycogen Corporation The subject invention concerns Bacillus thuringiensis isolates designated B.t. PS157C1, B.t. PS86A1, and B.t. PS75J1, which are active against aphid pests. Thus, these isolates, or variants thereof, can be used to control such pests. Further, genes encoding novel delta-endotoxins can be removed from these isolates and transferred to other host microbes, or plants. Expression of the delta-endotoxins in microbe hosts results in the control of aphid pests, whereas transformed plants become resistant to aphid pests.
Oppermann Herman; Ozkaynak Engin; Kubemsampath Thangavel; Rueger David C Medway, MA, UNITED STATES assigned to Stryker Corporation Disclosed are (1) osteogenic devices comprising a matrix containing substantially pure natural-sourced mammalian osteogenic protein; (2) DNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogenic proteins; (3) vectors carrying sequences encoding these novel polypeptide chains and host cells transfected with these vectors; (4) methods of producing these polypeptide chains using recombinant DNA technology; (5) antibodies specific for these novel polypeptide chains; (6) osteogenic devices comprising these recombinantly produced proteins in association with an appropriate carrier matrix; and (7) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals.
5468639 5468852 ISOLATED
DNA MOLECULE
ENCODING SHETZ SHIGELLA FLEXNERI
OF 2A
OLIGONUCLEOTIDES FOR DETECTING BACTERIA
Fasano Alessi; Levine Myron M; Nataro James P; Noriega Fernando Ellicott City, MD, UNITED STATES assigned to University of Maryland at Baltimore
Ohashi Tetsu; Tada Jun; Fukushima Shiger; Ozaki Hiroko; Nishimura Naoyuk; Shirasaki Yoshinari; Yamagata Koichi Kyoto, JAPAN assigned to Shimadzu Corporation
Substantially pure enterotoxins of Shigella flexneri 2a are described, along with a method for obtaining the same, antibodies having binding specificity to the enterotoxins and a method for use of the enterotoxins to develop a non-reactogenic Shigella flexneri
Oligonucleotides (SEQ ID NOs 1-8) selectively hybridizable with a specific gene of Vibro parahaemolyticus, oligonucleotides (SEQ ID NOs 9-13) selectively hybridizable with the LT gene of toxigenic Escherichia coil, oligonucleotides (SEQ ID NOs 14-21) selectively hybrizable with the STh or STp
proteins, and antibodies bind the ax1 receptor.
which specifically
75
2a vaccine candidate. 5468845
5468636
ANTIBODIES
TO OSTEOGENIC PROTEINS
BACILLUS THURINGIENSIS FOR CONTROLLING PESTS IN THE FAMILY
APHIDIDAE
Payne Jewel M; Cannon Raymond J; Schnepf H Ernest; Schwab George E San Diego, CA, UNITED STATES assigned to Mycogen Corporation The subject invention concerns Bacillus thuringiensis isolates designated B.t. PS157C1, B.t. PS86A1, and B.t. PS75J1, which are active against aphid pests. Thus, these isolates, or variants thereof, can be used to control such pests. Further, genes encoding novel delta-endotoxins can be removed from these isolates and transferred to other host microbes, or plants. Expression of the delta-endotoxins in microbe hosts results in the control of aphid pests, whereas transformed plants become resistant to aphid pests.
Oppermann Herman; Ozkaynak Engin; Kubemsampath Thangavel; Rueger David C Medway, MA, UNITED STATES assigned to Stryker Corporation Disclosed are (1) osteogenic devices comprising a matrix containing substantially pure natural-sourced mammalian osteogenic protein; (2) DNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogenic proteins; (3) vectors carrying sequences encoding these novel polypeptide chains and host cells transfected with these vectors; (4) methods of producing these polypeptide chains using recombinant DNA technology; (5) antibodies specific for these novel polypeptide chains; (6) osteogenic devices comprising these recombinantly produced proteins in association with an appropriate carrier matrix; and (7) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals.
5468639 5468852 ISOLATED
DNA MOLECULE
ENCODING SHETZ SHIGELLA FLEXNERI
OF 2A
OLIGONUCLEOTIDES FOR DETECTING BACTERIA
Fasano Alessi; Levine Myron M; Nataro James P; Noriega Fernando Ellicott City, MD, UNITED STATES assigned to University of Maryland at Baltimore
Ohashi Tetsu; Tada Jun; Fukushima Shiger; Ozaki Hiroko; Nishimura Naoyuk; Shirasaki Yoshinari; Yamagata Koichi Kyoto, JAPAN assigned to Shimadzu Corporation
Substantially pure enterotoxins of Shigella flexneri 2a are described, along with a method for obtaining the same, antibodies having binding specificity to the enterotoxins and a method for use of the enterotoxins to develop a non-reactogenic Shigella flexneri
Oligonucleotides (SEQ ID NOs 1-8) selectively hybridizable with a specific gene of Vibro parahaemolyticus, oligonucleotides (SEQ ID NOs 9-13) selectively hybridizable with the LT gene of toxigenic Escherichia coil, oligonucleotides (SEQ ID NOs 14-21) selectively hybrizable with the STh or STp