- Email: [email protected]
5549898 Immunogenic anaplasma marginale surface antigens, compositions, and methods of use
PATENT ABSTRACTS
5549830 REVERSE OSMOSIS AND ULTRAFILTRATION METHODS FOR SOLUTIONS TO ISOLATE DESIRED SOLUTES INCLUDING TAXANE Carver David; Prout Timothy R; Workman Christopher T; Hughes Charles L Boulder, CO, UNITED STATES Assigned to NaPro BioTherapeutics lnc A method of processing a feed liquid in the form of an extraction solution containingtaxane solutes that is an extraction product of a biomass utilizes at least one semipermeable membrane to remove at least one taxane solute from the solvent by reverse osmosis. The feed liquid is placed in a first region on one side of the membrane and pressure is supplied to transport constitutes of the feed liquid across the membrane to a second region as a first permeate while retaining a first retentate in the first region. The taxane solute may be either retained or transported. Where the taxane solute is transported, the method can further include the use of a second semipermeable membrane of a pore size different from the first membrane and supplying a pressure to transport some of the first permeate across the second membrane as a second permeate while retaining a majority of the desired taxane solute as a second retentate. Here, the first membrane has a pore size which allows transport of the taxane solute while the second membrane has a pore size that retains the taxane solute. A variety of solvents and useable membranes is disclosed.
5549896 HEPATITIS A VIRUS STRAIN, METHOD FOR THE ISOLATION OF NEW HEPATITIS A VIRUS STRAINS AND HEPATITIS A VACCINES Gluml uck Reinhard; Brantschen Stefan Spiegel/Bern, SWITZERLAND Assigned to Schweiz Serum- & Impfinstitut Bern The invention relates to hepatitis A viruses (HAVs) having a serotype displaying the
419
immunological characteristics of the HAV slJain RG-SB XAII2 (CNCM 1-1080). In particular, the invention relates to the new hepatitis A virus strain RG-SB XAI12 (CNCM 1-1080). The lavantion also relates to structural components of said HAVs. ~rthennore, the invention relates to processes for the isolation of said HAVs. The HAVs of the present invention and the smtctural components thereof can be used for the production of vaccines and diagnostic compositions. Finally,the invention relates to polyclonal and monoclonal antibodies which am direct~ to said new HAVs.
5~9~8 IMMUNOGENIC ANAPLASMA MARGINALE SURFACE ANTIGENS, COMPOSITIONS, AND METHODS OF USE McGuire Travis; Palmer Guy; Barbet Anthony; Davis William Pullman, WA, UNITED STATES
A purifiedantigenicsurfaceproteinof Anaplasma marginale has been identified, and is capable of inducing immune responses in ruminants which neutralizes virulent Anaplasma marginale. The antigenic surface protein has a molecular weight of about 105,000 daltons, and can be purified by an immonoaffinity chromatography process. The antigen has further utility in diagnostic tests for anaplasmosis. It can be synthesized by polypeptideprocedures or by genetic engineering. DNA and amino acid sequences have been developed for the antigen according to this invention. The antigen is useful as a vaccine component for protecting mammals against infection by Anaplasma marginale and may be useful for rickettsial organisms other than Anaplasma marginale.
5549920 EXTRUSION INACTIVATION OF PROTEASE ENZYME IN FISH AND FISH FOOD PRODUCTS Choudhury Gour S Kodiak, AK, UNITED S T A T E SAssignedtoUniversityofAlaska
5549830 REVERSE OSMOSIS AND ULTRAFILTRATION METHODS FOR SOLUTIONS TO ISOLATE DESIRED SOLUTES INCLUDING TAXANE Carver David; Prout Timothy R; Workman Christopher T; Hughes Charles L Boulder, CO, UNITED STATES Assigned to NaPro BioTherapeutics lnc A method of processing a feed liquid in the form of an extraction solution containingtaxane solutes that is an extraction product of a biomass utilizes at least one semipermeable membrane to remove at least one taxane solute from the solvent by reverse osmosis. The feed liquid is placed in a first region on one side of the membrane and pressure is supplied to transport constitutes of the feed liquid across the membrane to a second region as a first permeate while retaining a first retentate in the first region. The taxane solute may be either retained or transported. Where the taxane solute is transported, the method can further include the use of a second semipermeable membrane of a pore size different from the first membrane and supplying a pressure to transport some of the first permeate across the second membrane as a second permeate while retaining a majority of the desired taxane solute as a second retentate. Here, the first membrane has a pore size which allows transport of the taxane solute while the second membrane has a pore size that retains the taxane solute. A variety of solvents and useable membranes is disclosed.
5549896 HEPATITIS A VIRUS STRAIN, METHOD FOR THE ISOLATION OF NEW HEPATITIS A VIRUS STRAINS AND HEPATITIS A VACCINES Gluml uck Reinhard; Brantschen Stefan Spiegel/Bern, SWITZERLAND Assigned to Schweiz Serum- & Impfinstitut Bern The invention relates to hepatitis A viruses (HAVs) having a serotype displaying the
419
immunological characteristics of the HAV slJain RG-SB XAII2 (CNCM 1-1080). In particular, the invention relates to the new hepatitis A virus strain RG-SB XAI12 (CNCM 1-1080). The lavantion also relates to structural components of said HAVs. ~rthennore, the invention relates to processes for the isolation of said HAVs. The HAVs of the present invention and the smtctural components thereof can be used for the production of vaccines and diagnostic compositions. Finally,the invention relates to polyclonal and monoclonal antibodies which am direct~ to said new HAVs.
5~9~8 IMMUNOGENIC ANAPLASMA MARGINALE SURFACE ANTIGENS, COMPOSITIONS, AND METHODS OF USE McGuire Travis; Palmer Guy; Barbet Anthony; Davis William Pullman, WA, UNITED STATES
A purifiedantigenicsurfaceproteinof Anaplasma marginale has been identified, and is capable of inducing immune responses in ruminants which neutralizes virulent Anaplasma marginale. The antigenic surface protein has a molecular weight of about 105,000 daltons, and can be purified by an immonoaffinity chromatography process. The antigen has further utility in diagnostic tests for anaplasmosis. It can be synthesized by polypeptideprocedures or by genetic engineering. DNA and amino acid sequences have been developed for the antigen according to this invention. The antigen is useful as a vaccine component for protecting mammals against infection by Anaplasma marginale and may be useful for rickettsial organisms other than Anaplasma marginale.
5549920 EXTRUSION INACTIVATION OF PROTEASE ENZYME IN FISH AND FISH FOOD PRODUCTS Choudhury Gour S Kodiak, AK, UNITED S T A T E SAssignedtoUniversityofAlaska