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5559211 Biologically active product produced by streptococcus pyogenes and method of purification
452
PATENT ABSTRACTS
5559210
5559212
REAGENTS A N D M E T H O D S FOR THE D E T E C T I O N AND Q U A N T I F I C A T I O N OF T E S T O S T E R O N E IN FLUID SAMPLES
FROG E M B R Y O AND EGG-DERIVED T U M O R CELL ANTI-PROLIFERATION PROTEIN
Adamczyk Macie; Chen Yon-Yih; Walling John; James Bryan; Artip Sharon Guroee, IL, UNITED STATES Assigned to Abbott Laboratories A Position 1 immunogen having the following formula: (*See Patent for Chemical Structure*) wherein: (a) P represents an immunogenic carrier material (b) X represents a linking moiety wherein -X-P is attached to a testosterone derivative (c) n is from 1 to 10, inclusive (d) the degree of substitution of P by the testosterone derivative is from 1 to 100%, inclusive.
Ardelt Wojciech J Passaic, NJ, UNITED STATES Assigned to Alfacell Corporation Rana pipiens eggs are subjected to fertilization and the embryos are grown to a predetermined stage of development. The embryos and unfertilized eggs are then subjected to mechanical processing in the presence of a weakly acidic buffer to produce an extract. The extract is subjected to ion-exchange chromatography and size-exclusion chromatography. The resulting pharmaceutical has activity against certain cancer cells. The amino acid sequence and composition of the pharmaceutical are disclosed.
5560827 EXCLUSION CHROMATOGRAPHIC SEPARATION OF IONIC FROM NONIONIC SOLUTES 5559211 B I O L O G I C A L L Y ACTIVE P R O D U C T P R O D U C E D BY S T R E P T O C O C C U S PYOGENES AND M E T H O D OF PURIFICATION Kumagal Katsu; Rikiishi Hidem; Tamura Keiji;Sugawara Shunj; Nemoto Eiji; Okamoto Shigefum; Onta Tokio Sendai, JAPAN Assigned to Kabushiki Kalsha Saikin Kagaku Kenkyujo A biologically active, stable protein with a molecular weight of 20,000 to 30,000 and an iscelectric point of 8.0-10.0 is produced from the culture fluid of Streptococcus pyogenes and purified. The purified biologically active protein produces lymphocyte proliferation, provides protection against bacterial and viral infection and restricts minor metastasis.
Hester Roger D; Farina George Hattiesburg, MS, UNITED STATES Assigned to Tennessee Valley Authority; University of Southern Mississip A process for effectively and economically separating an ionic component such as acid from a nonionic component such as sugar in polar solutions using ion exclusion technology whereby the viability of using hydrolysis to convert wood and agricultural waste products such as corn stover into fuel alcohol is substantially effected. Underlying the gist of this invention are newly discovered methods by which dispersion, caused by shrinkage of resin within ion exclusion columns, is controlled resulting in operation of such columns, over a wide range of process conditions to produce separate and distinct elution profiles for the acid and sugar. Successful operation of these new ion exclusion methods, techniques, and systems can replace lime precipitation which currently is being used in acid hydrolysis processing. This not only obviates the
PATENT ABSTRACTS
5559210
5559212
REAGENTS A N D M E T H O D S FOR THE D E T E C T I O N AND Q U A N T I F I C A T I O N OF T E S T O S T E R O N E IN FLUID SAMPLES
FROG E M B R Y O AND EGG-DERIVED T U M O R CELL ANTI-PROLIFERATION PROTEIN
Adamczyk Macie; Chen Yon-Yih; Walling John; James Bryan; Artip Sharon Guroee, IL, UNITED STATES Assigned to Abbott Laboratories A Position 1 immunogen having the following formula: (*See Patent for Chemical Structure*) wherein: (a) P represents an immunogenic carrier material (b) X represents a linking moiety wherein -X-P is attached to a testosterone derivative (c) n is from 1 to 10, inclusive (d) the degree of substitution of P by the testosterone derivative is from 1 to 100%, inclusive.
Ardelt Wojciech J Passaic, NJ, UNITED STATES Assigned to Alfacell Corporation Rana pipiens eggs are subjected to fertilization and the embryos are grown to a predetermined stage of development. The embryos and unfertilized eggs are then subjected to mechanical processing in the presence of a weakly acidic buffer to produce an extract. The extract is subjected to ion-exchange chromatography and size-exclusion chromatography. The resulting pharmaceutical has activity against certain cancer cells. The amino acid sequence and composition of the pharmaceutical are disclosed.
5560827 EXCLUSION CHROMATOGRAPHIC SEPARATION OF IONIC FROM NONIONIC SOLUTES 5559211 B I O L O G I C A L L Y ACTIVE P R O D U C T P R O D U C E D BY S T R E P T O C O C C U S PYOGENES AND M E T H O D OF PURIFICATION Kumagal Katsu; Rikiishi Hidem; Tamura Keiji;Sugawara Shunj; Nemoto Eiji; Okamoto Shigefum; Onta Tokio Sendai, JAPAN Assigned to Kabushiki Kalsha Saikin Kagaku Kenkyujo A biologically active, stable protein with a molecular weight of 20,000 to 30,000 and an iscelectric point of 8.0-10.0 is produced from the culture fluid of Streptococcus pyogenes and purified. The purified biologically active protein produces lymphocyte proliferation, provides protection against bacterial and viral infection and restricts minor metastasis.
Hester Roger D; Farina George Hattiesburg, MS, UNITED STATES Assigned to Tennessee Valley Authority; University of Southern Mississip A process for effectively and economically separating an ionic component such as acid from a nonionic component such as sugar in polar solutions using ion exclusion technology whereby the viability of using hydrolysis to convert wood and agricultural waste products such as corn stover into fuel alcohol is substantially effected. Underlying the gist of this invention are newly discovered methods by which dispersion, caused by shrinkage of resin within ion exclusion columns, is controlled resulting in operation of such columns, over a wide range of process conditions to produce separate and distinct elution profiles for the acid and sugar. Successful operation of these new ion exclusion methods, techniques, and systems can replace lime precipitation which currently is being used in acid hydrolysis processing. This not only obviates the