PATENT ABSTRACTS
need for the large quantities of acid and lime required therein, but also eliminates the unwanted and highly ecologically undesirable production of huge quantities of waste gypsum.
453
associated with lung neoplasias in sputum specimens which contain mutations and reagents therefor are described.
5561043
5560828 METHOD FOR THE REMOVAL OF COMPONENTS CAUSING TURBIDITY, FROM A FLUID, BY MEANS OF MICROFILTRATION Wenten Gede; Keenhen Dirk; Roesink Hendrik D W; Rasmussen Ala; Jonsson Gunna Bali, INDONESIA Assigned to X-How B V The invention relates to a process for the removal of components causing turbidity, from a fluid, by means of microfiltratiun, whereby the fluid is beer, wine,fruit juice, bacterial suspension, blood, milk, enzyme suspension, etc. According to the invention, the fluid to be treated is fed across an asymmetric membrane having a pore structure such that the pores on the feed side of the membrane are larger than the nominal pore size and the pores of nominal pore size occur in the cross section toward the permeate side, the filtered off components are back-flushed from the membrane and are subsequently carried away with the fluid. The nominal pore size is usually 0.1-5.0 mum and preferably 0.2-1.0 mum. The membrane may be tubular, flat or capillary. Back-flushing takes place intermittently with a frequency of 1 second to 10 minutes for 0.1-1 second at a counter pressure of 0.5-5 bar. The feed velocity is preferably below 2 m/s and the pressure difference over the membrane is less than 0.5 bar.
SELF-ASSEMBLING MULTIMERIC NUCLEIC CONSTRUCTS
ACID
Cantor Charles R; Niemeyer Christof M; Smith Cassandra; Sano Takeshi; Hnatowich Donald J; Rusckowski Mar Boston, MA, UNITED STATES Assigned to Trustees of Boston University The invention is directed to constructs and compositions containing multimeric forms of nucleic acid. Multimeric nucleic acids comprise single-stranded nucleic acids attached via biotin to streptavidin and bound with a functional group. These constructs can be utilized in vivo to treat or identify diseased tissue or cells. Repeated administrations of multimeric nucleic acid compositions produce a rapid and specific ampfification of nucleic acid constructs and their attached functional groups. For twamnent purposes, functional groups may be toxins, radioisotopes, genes or enzymes. Diagnostically, labeled multimeric constructs may be used to identify specific targets in vivo or in vitro. Multimeric nucleic acids may also be used in nanotechnology and to create self-assembling polymeric aggregates such as membranes of defined porosity, microcircuits and many other products.
5561044 5561041 NUCLEIC ACID MUTATION DETECTION BY ANALYSIS OF SPUTUM Sidransky Davi Baltimore, MD, UNITED STATES Assigned to The Johns Hopkins University School of Medicine Methods for detection of target nucleic acids
DETECTION OF MYCOBACTERIA BY MULTIPLEX STRAND DISPLACEMENT NUCLEIC ACID AMPLIFICATION Walker George T; Nadean James G; Spears Patricia A; Nycz Colleen M; Shank Duryl D; Schram James L; Jurgnnsen Stewart R Chapel Hill, NC, UNITED STATES Assigned to Becton Dickinson and Company