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5595903 Genetically engineered human acetylcholinesterase
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PATENT ABSTRACTS
5595899 M E T H O D S OF I N T R O D U C I N G F O R E I G N D N A INTO CELLS
Phage display methods were used to identify mimetics of SDI-1. Such mimetics are small peptides that are capable of binding to cyclin molecules, especially CDK2. The invention is directed to the mimetics and to methods for producing them.
Sato Masahiro; Tada Nobuhiro Kawagoe, JAPAN Assigned to Hoechst Japan Limited The present invention provides an easy and efficient method of introducing a foreign DNA into certain cells which have been considered difficult to be transformed by conventional methods. The present inventors have found that bis-benzimdazolyl compounds which specifically bind to DNA were useful as a carrier to introduce the DNA into a target cell. Foreign DNA was introduced into a host cell by exposing said cell to a suspension or a solution containing the foreign DNA-compound complex.
5595903 GENETICALLY ENGINEERED HUMAN ACETYLCHOLINESTERASE Soreq Hermon; Haim Zakut Rishon Le Zion, ISRAEL Assigned to Yissum Research Development Co of the Hebrew University of Jerusalem Genetically engineered human acetylcholinesterase and antibodies that define the protein are described. These composition may be used in pharmaceutical preparations for treatment and prophylaxis of organo-phosphorous compound poisoning or post-operative apnea. Also described are human cholinesterase DNA probes which may be employed for diagnosing progressing ovarian carcinomas and hemocytopoietic disorders.
5596079 M I M E T I C S OF SENESCENT CELL D E R I V E D INHIBITORS OF DNA SYNTHESIS Smith James R; Kay Brian UNITED STATES
Houston, TX,
5596089 OLIGONUCLEOTIDE PROBE A N D PRIMERS SPECIFIC TO BOVINE OR P O R C I N E M A L E G E N O M I C DNA Silversides David; Daneau Isabelle M; Houde Alain St Hyacinthe, CANADA Assigned to Universite De Montreal The present invention relates to novel bovine (SEQ ID NO:l) and porcine (SEQ ID NO:2) genomic sequences for the SRY gene along with oligonucleotide primers. The present invention also relates to a method of sexing bovine or porcine tissue by descriminating PCR products obtained by amplification of specific DNA or eDNA sequences of bovine or porcine tissue which is used as a DNA template and wherein two pairs of DNA primers are used for the PCR. The present invention also relates to a method for the genetic manipulation or selection of sexual phenotype in domesticated animals, which comprises using transgenes composed of SRY sequences to cause and control the expression of genetic ablation sequences and genetic switching sequences in undifferentiated and developing gonadal tissues of both XX and XY animals.
5597689 N U C L E O T I D E SEQUENCES PERMITTING THE REPLICATION AND M A I N T E N A N C E OF A GENETIC I N F O R M A T I O N IN A N I M A L CELLS Devauchelle Gacu erard; Cemtti Martine; Persillon Cacu ecile Saint Christol Les Ales, FRANCE Assigned to Institut National de la Recherche Agronomique (I N R A); Centre National de la Recherche Scientifique (C N R S)
PATENT ABSTRACTS
5595899 M E T H O D S OF I N T R O D U C I N G F O R E I G N D N A INTO CELLS
Phage display methods were used to identify mimetics of SDI-1. Such mimetics are small peptides that are capable of binding to cyclin molecules, especially CDK2. The invention is directed to the mimetics and to methods for producing them.
Sato Masahiro; Tada Nobuhiro Kawagoe, JAPAN Assigned to Hoechst Japan Limited The present invention provides an easy and efficient method of introducing a foreign DNA into certain cells which have been considered difficult to be transformed by conventional methods. The present inventors have found that bis-benzimdazolyl compounds which specifically bind to DNA were useful as a carrier to introduce the DNA into a target cell. Foreign DNA was introduced into a host cell by exposing said cell to a suspension or a solution containing the foreign DNA-compound complex.
5595903 GENETICALLY ENGINEERED HUMAN ACETYLCHOLINESTERASE Soreq Hermon; Haim Zakut Rishon Le Zion, ISRAEL Assigned to Yissum Research Development Co of the Hebrew University of Jerusalem Genetically engineered human acetylcholinesterase and antibodies that define the protein are described. These composition may be used in pharmaceutical preparations for treatment and prophylaxis of organo-phosphorous compound poisoning or post-operative apnea. Also described are human cholinesterase DNA probes which may be employed for diagnosing progressing ovarian carcinomas and hemocytopoietic disorders.
5596079 M I M E T I C S OF SENESCENT CELL D E R I V E D INHIBITORS OF DNA SYNTHESIS Smith James R; Kay Brian UNITED STATES
Houston, TX,
5596089 OLIGONUCLEOTIDE PROBE A N D PRIMERS SPECIFIC TO BOVINE OR P O R C I N E M A L E G E N O M I C DNA Silversides David; Daneau Isabelle M; Houde Alain St Hyacinthe, CANADA Assigned to Universite De Montreal The present invention relates to novel bovine (SEQ ID NO:l) and porcine (SEQ ID NO:2) genomic sequences for the SRY gene along with oligonucleotide primers. The present invention also relates to a method of sexing bovine or porcine tissue by descriminating PCR products obtained by amplification of specific DNA or eDNA sequences of bovine or porcine tissue which is used as a DNA template and wherein two pairs of DNA primers are used for the PCR. The present invention also relates to a method for the genetic manipulation or selection of sexual phenotype in domesticated animals, which comprises using transgenes composed of SRY sequences to cause and control the expression of genetic ablation sequences and genetic switching sequences in undifferentiated and developing gonadal tissues of both XX and XY animals.
5597689 N U C L E O T I D E SEQUENCES PERMITTING THE REPLICATION AND M A I N T E N A N C E OF A GENETIC I N F O R M A T I O N IN A N I M A L CELLS Devauchelle Gacu erard; Cemtti Martine; Persillon Cacu ecile Saint Christol Les Ales, FRANCE Assigned to Institut National de la Recherche Agronomique (I N R A); Centre National de la Recherche Scientifique (C N R S)