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5607860 Dual chamber blood culture bottle
PATENT ABSTRACTS
can also be chemically synthesized. Disclosed are the uses of the protein, peptides and oligopeptides as antigens for vaccine formulations, and as antigens in diagnostic immunoassays. The nucleotide sequences are useful for constructing vectors for use as vaccines for insertions into attenuated bacteria in constructing a recombinant bacterial vaccine and for inserting into a viral vector in constructing a recombinant viral vaccine. Also described is the use of nucleotide sequences related to the gene encoding E as primers and/or probes in molecular diagnostic assays for the detection of M. catarrhalis.
753
simultaneously into two independent sample vials. Independent culture chambers contain growth media, one culture chamber preferably containing an aerobic growth medium and another culture chamber preferably containing an anaerobic growth medium. The device is configured to isolate the sample vials and culture chambers from contaminants of the external environment. Further, means are provided for releasing the blood from one sample vial into one culture chamber while simultaneously releasing the blood from the other sample vial into the other culture chamber. In the preferred embodiment, outer walls of the device are constructed of transparent plastic so as to enable visual observance of microorganism growth in the respective culture chambers.
5607851 PROCESS FOR PURIFYING HEPATITIS A VIRUS (HAV), AND VACCINE COMPOSITIONS CONTAINING HEPATITIS A VIRUS
5607863 BARRIER-CONTROLLED ASSAY
Pellegrini Vittoria; Fineschi Nicoletta; Zuckerman Arie J Siena, ITALY Assigned to Biocine S p A A process is described for the purification of the hepatitis A virus, which allows one to obtain with good yields a pure product, in which organic material collected by centrifugation after lysis of the culture cells is submitted to gel filtration and successively to ion exchange chromatography.
5607860 DUAL CHAMBER BLOOD CULTURE BOTTLE Gombrich Peter P; Domanik Richard A; Mayer William Chicago, IL, UNITED STATES Assigned to Accumed Inc A multi-chambered blood culture device for simultaneously conducting two blood culture tests on a single blood sample. An integrated unit is provided for receiving a blood sample
DEVICE
Chandler Howard M Yarmouth, ME, UNITED STATES Assigned to SmithKline Diagnostics Inc An assay device for detection and/or determination of an analyte in a test sample uses a barrier containing an aperture to control the application of reagents to the device for greater reproducibility of results. In its simplest form, the device comprises: (1) a chromatographic medium having a first end, a second end, and fLrst and second surfaces, and having a specific binding partner for the analyte immobilized thereto in a detection zone; (2) at least one absorber in operable contact with at least one of the first and second ends; and (3) a substantially fluid-impermeable barrier adjacent to the fu,st surface of the chromatographic medium, the barrier having at least one aperture therethrough for application of liquid to the chromatographic medium, the bamer at least partially blocking application of liquid to the chromatographic medium. The device can be adapted for shmdwich or competitive assays and can be used to perform amplified assays, such as those using silver amplification or enzyme amplification. Various arrangements of components within the device are possible, and elements such as filters can be accommodated.
can also be chemically synthesized. Disclosed are the uses of the protein, peptides and oligopeptides as antigens for vaccine formulations, and as antigens in diagnostic immunoassays. The nucleotide sequences are useful for constructing vectors for use as vaccines for insertions into attenuated bacteria in constructing a recombinant bacterial vaccine and for inserting into a viral vector in constructing a recombinant viral vaccine. Also described is the use of nucleotide sequences related to the gene encoding E as primers and/or probes in molecular diagnostic assays for the detection of M. catarrhalis.
753
simultaneously into two independent sample vials. Independent culture chambers contain growth media, one culture chamber preferably containing an aerobic growth medium and another culture chamber preferably containing an anaerobic growth medium. The device is configured to isolate the sample vials and culture chambers from contaminants of the external environment. Further, means are provided for releasing the blood from one sample vial into one culture chamber while simultaneously releasing the blood from the other sample vial into the other culture chamber. In the preferred embodiment, outer walls of the device are constructed of transparent plastic so as to enable visual observance of microorganism growth in the respective culture chambers.
5607851 PROCESS FOR PURIFYING HEPATITIS A VIRUS (HAV), AND VACCINE COMPOSITIONS CONTAINING HEPATITIS A VIRUS
5607863 BARRIER-CONTROLLED ASSAY
Pellegrini Vittoria; Fineschi Nicoletta; Zuckerman Arie J Siena, ITALY Assigned to Biocine S p A A process is described for the purification of the hepatitis A virus, which allows one to obtain with good yields a pure product, in which organic material collected by centrifugation after lysis of the culture cells is submitted to gel filtration and successively to ion exchange chromatography.
5607860 DUAL CHAMBER BLOOD CULTURE BOTTLE Gombrich Peter P; Domanik Richard A; Mayer William Chicago, IL, UNITED STATES Assigned to Accumed Inc A multi-chambered blood culture device for simultaneously conducting two blood culture tests on a single blood sample. An integrated unit is provided for receiving a blood sample
DEVICE
Chandler Howard M Yarmouth, ME, UNITED STATES Assigned to SmithKline Diagnostics Inc An assay device for detection and/or determination of an analyte in a test sample uses a barrier containing an aperture to control the application of reagents to the device for greater reproducibility of results. In its simplest form, the device comprises: (1) a chromatographic medium having a first end, a second end, and fLrst and second surfaces, and having a specific binding partner for the analyte immobilized thereto in a detection zone; (2) at least one absorber in operable contact with at least one of the first and second ends; and (3) a substantially fluid-impermeable barrier adjacent to the fu,st surface of the chromatographic medium, the barrier having at least one aperture therethrough for application of liquid to the chromatographic medium, the bamer at least partially blocking application of liquid to the chromatographic medium. The device can be adapted for shmdwich or competitive assays and can be used to perform amplified assays, such as those using silver amplification or enzyme amplification. Various arrangements of components within the device are possible, and elements such as filters can be accommodated.