RUFKLGHFWRP\)UHTXHQF\RI7HVWLFXODU7RUVLRQZDVKLJKHUGXULQJWKHFROGHUKDOI RIWKH\HDUS Conclusions: 2XUGDWDVKRZHGWKDWWHVWLFXODUWRUVLRQZDVWKHPRVWFRPPRQᚏQGLQJ DWVXUJLFDOH[SORUDWLRQIROORZHGE\WRUVLRQRIWHVWLFXODUDSSHQGDJHV$JHKDGOLPLWHG YDOXHLQGLDJQRVLQJWKHFDXVHRIDFXWHVFURWDOSDLQ,QFUHDVHLQSXEOLFDZDUHQHVVLV QHHGHGWRUHGXFHRUFKLGHFWRP\UDWHV7HVWLFXODUWRUVLRQZDVDVVRFLDWHGZLWKFROG ZHDWKHU2XUᚏQGLQJVVXSSRUWWKHSUDFWLFHRIVXUJLFDOH[SORUDWLRQIRUDFXWHVFURWDO SDLQVXVSLFLRXVRIWHVWLFXODUWRUVLRQLQSDWLHQWVRIDQ\DJH
808
ANTI-OXIDANT AND SELECTIVE CYCLOOXYGENASE 2 INHIBITOR COMBINATION IN A RAT TESTICULAR TORSION MODEL: DOES IT REALLY WORK?
*XURFDN68UH,&XPDRJOX$*RQXO,,$ULFLRJOX$%R]NLUOL, 1 Gazi University School of Medicine, Dept. of Urology, Ankara, Turkey, 2Gazi University School of Medicine, Dept. of Medical Biochemistry, Ankara, Turkey, 3 Gazi University School of Medicine, Dept. of Medical Pathology, Ankara, Turkey Introduction & Objectives: ,Q WKLV VWXG\ ZH DLPHG WR LQYHVWLJDWH ZKHWKHU WKH FRPELQDWLRQ WUHDWPHQW RI DQ DQWLR[LGDQW /FDUQLWLQH DQG D VHOHFWLYH F\FORR[\JHQDVH &2; LQKLELWRU PHOR[LFDP LV HᚎHFWLYH LQ WKH WUHDWPHQW RI FHOOXODUGDPDJHFDXVHGE\WHVWLFXODUWRUVLRQ Material & Methods: PDOH ZLVWDU UDWV ZHUH UDQGRPO\ GLYLGHG LQWR JURXSV &RQWUROJURXSFRPSRVHGRIVKDPRSHUDWLRQDQGVHFRQGJURXSXQGHUZHQWWRUVLRQ GHWRUVLRQIRUPLQXWHV*URXSDQGUHFHLYHG/FDUQLWLQHPJNJGD\ DQG PHOR[LFDPH PJNJGD\ UHVSHFWLYHO\ LQ DGGLWLRQ WR WKH VDPH WRUVLRQGHWRUVLRQ SURFHGXUH*URXSZDVVXEMHFWHGWRWKHPD[LPXPWUHDWPHQWZLWK/FDUQLWLQHDQG PHOR[LFDPDIWHUWRUVLRQGHWRUVLRQ%LODWHUDORUFKLHFWRP\ZDVSHUIRUPHGKRXUV DIWHUWKHRSHUDWLRQLQDOOJURXSV+LVWRSDWKRORJLFDQDO\VLVZDVSHUIRUPHGDFFRUGLQJ WR&RVHQWLQRಬVFODVVLᚏFDWLRQV\VWHP,QDGGLWLRQFDWDODVH&$7 0DORQGLDOGHK\GH 0'$ DQG /LSLG K\GURSHUR[LGDVH /+3 DFWLYLWLHV ZHUH ELRFKHPLFDOO\ PHDVXUHG LQWKHWHVWHV Results: /FDUQLWLQHPHOR[LFDPDQGFRPELQDWLRQWKHUDS\UHVXOWHGLQDVWDWLVWLFDOO\ VLJQLᚏFDQWGHFUHDVHLQ0'$DFWLYLW\LQXQLODWHUDOWHVWLFXODUWRUVLRQGHWRUVLRQPRGHO S S DQG S $OWKRXJK VWDWLVWLFDOO\ LQVLJQLᚏFDQW &$7 DFWLYLW\ LQFUHDVHG DIWHU PHOR[LFDP WUHDWPHQW S DQG /+3 DFWLYLW\ GHFUHDVHG DIWHU /&DUQLWLQH WUHDWPHQW S ,Q DGGLWLRQ WUHDWPHQW ZLWK /FDUQLWLQH FDXVHG D VLJQLᚏFDQWGHFUHDVHLQ&RVHQWLQRJUDGHFRPSDUHGWRJURXSS Conclusions: 7KHUHVXOWVRIWKLVVWXG\KDYHVKRZQWKDW/FDUQLWLQHKDV GHᚏQLWH EHQHᚏFLDO HᚎHFWV RQ FHOOXODU GDPDJH DIWHU WHVWLFXODU WRUVLRQGHWRUVLRQ SUREDEO\ WKURXJKLWVZHOONQRZQDQWLR[LGDQWHᚎHFWV$OWKRXJKXQHTXDOO\HᚎHFWLYHVHOHFWLYH F\FORR[\JHQDVH LQKLELWLRQ VHHPV WR H[HUW LWV DQWLLQᚐDPDWRU\ HᚎHFWV WKURXJK LQKLELWLRQ RI F\WRNLQH UHOHDVH LQ UHVSRQVH WR WRUVLRQ 6R FRPELQDWLRQ WKHUDS\ RI WKHVH DJHQWV PLJKW EH FKRVHQ IRU WKH PRVW UHSURGXFWLYH WUHDWPHQW RI WHVWLFXODU WRUVLRQDWFHOOXODUOHYHO
809
TESTICULAR SIZE AND CATCH-UP GROWTH AFTER LYMPHATIC-SPARING AND LYMPHATIC NON-SPARING VARICOCELE REPAIR IN CHILDREN AND ADOLESCENTS
.RFYDUD56HGO£ÏHN-'¯WÝ='YRě£ÏHN- General University Hospital and 1st Faculty of Medicine of Charles University, Dept. of Urology, Prague, Czech Republic Introduction & Objectives: 'LYLVLRQRIO\PSKDWLFYHVVHOVGXULQJYDULFRFHOHFWRP\ PD\ OHDG WR K\GURFHOH IRUPDWLRQ DQG GHYHORSPHQW RI WHVWLFXODU K\SHUWURSK\ DVVRFLDWHGZLWKLQWUDWHVWLFXODURHGHPD:HVWXGLHGWKHWHVWLFXODUJURZWKWKURXJK WKH DGROHVFHQFH LQ UHODWLRQ WR WKH SXEHUWDO VWDJH DQG WR WKH W\SH RI WKH UHSDLU O\PSKDWLFVSDULQJDQGO\PSKDWLFQRQVSDULQJ Material & Methods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ᚎHUHQFHLQWHVWLFXODU VL]HJUHDWHUWKDQFFZDVFRQVLGHUHGK\SRSODVWLF+\SHUWURSK\RIWKHOHIWWHVWLFOH DIWHUYDULFRFHOHFWRP\ZDVGHᚏQHGDVDWOHDVWDLQFUHDVHLQVL]HRYHUWKHULJKW WHVWLFOH Results: %HIRUHUHSDLUWKHPHDQOHIWWHVWLFXODUVL]H/76 ZDVFFWKHDWURSK\ LQGH[$, DQGGLᚎHUHQFHLQWHVWLFXODUVL]H'76 FFLQWKH/6JURXSDQG FFDQGFFLQWKH/16JURXSUHVS$IWHUWKHPHDQIROORZXSRI \LQ/6DQG\LQWKH/16JURXSWKH/76UHDFKHGFF$,DQG'76 FFLQWKH/6JURXSPHDQDJH\36 DQGFFDQGFFLQ WKH/16JURXSPHDQDJH\36 UHVS'LᚎHUHQFHVLQDOOSDUDPHWHUVZHUH KLJKO\VLJQLᚏFDQW6LPLODUVLJQLᚏFDQWGLᚎHUHQFHVZHUHIRXQGLQHDFKSXEHUWDOVWDJH DVZHOODVLQSDWLHQWVIURPWKH/6DQGIURPWKH/16JURXS ROGHUWKDQ \HDUVUDQJHWR ,QWKHVHSDWLHQWVWHVWLFXODUK\SRSODVLDZDVGHWHFWHGLQ EHIRUHDQGLQ DWIROORZXSLQWKH/6JURXSLQ DQG LQWKH/16JURXSUHVSWHVWLFXODUK\SHUWURSK\ZDVIRXQGLQ
DQG LQWKH/6DQG/16JURXSUHVS Conclusions: $IWHU O\PSKDWLF QRQVSDULQJ UHSDLU KLJKHU LQFUHDVH LQ WHVWLFXODU VL]HKDVEHHQIRXQGLQDOOSXEHUWDOVWDJHVH[FHHGLQJPRVWO\WKHVL]HRIWKHULJKW WHVWLVDQGUHᚐHFWLQJWKHLQWUDWHVWLFXODURHGHPD7KHUHIRUHWKHUHDOFDWFKXSJURZWK FDQ EH DVVHVVHG LQ PLFURVXUJLFDO O\PSKDWLFVSDULQJ UHSDLUV RQO\ WKH DEVROXWH GLᚎHUHQFHVEHWZHHQWKHERWKWHVWHVUHPDLQLQPRVWSDWLHQWV6XSSRUWHGE\*UDQW 150=&5
810
MODIFIED CLAVIEN CLASSIFICATION IN PERCUTANEOUS NEPHROLITHOTOMY: ASSESSMENT OF COMPLICATIONS IN CHILDREN
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Conclusions: 31/ LQ FKLOGUHQ LV VDIH DQG HᚎHFWLYH WKHUDS\ 6WRQH EXUGHQ KDV VLJQLᚏFDQWHᚎHFWRQFRPSOLFDWLRQUDWH&ODYLHQಬVJUDGLQJV\VWHPDOORZVXVWRUHSRUW WKHFRPSOLFDWLRQVLQDVWDQGDUGL]HGZD\
811
TRANSITIONING CARE OF COMPLEX PAEDIATRIC UROLOGICAL TO ADULT SERVICES
:RRG'1&DUU%5RELQVRQ.:RRGKRXVH&5- 1 University College London Hospitals, Dept. of Adolescent Urology, London, United Kingdom, 2Great Ormond Street Hospital, Dept. of Paediatric Urology, London, United Kingdom Introduction & Objectives: 7KH PRYH RI D FRPSOH[ XURORJLFDO SDWLHQW IURP D SDHGLDWULFKHDOWKFDUHHQYLURQPHQWWRDGXOWKHDOWKFDUHPD\UHVXOWLQDQXPEHURI GLᚑFXOWLHV7KH\PD\IRUPVWURQJDWWDFKPHQWVWRWKHLUSDHGLDWULFWHDPKDYLQJKDG PXOWLSOH RSHUDWLRQV $ IHZ KDYH FRPSOH[ LVVXHV WKDW KDYH EHHQ FRQᚏGHG LQ WKH WHDPWKH\NQRZZHOOEXWGLVFORVXUHLVXQOLNHO\WRIROORZLQWKHDGXOWHQYLURQPHQW IRUVRPHWLPH7KLVSDSHUH[DPLQHVWKHEHQHᚏWRIDGHGLFDWHGPXOWLGLVFLSOLQDU\ WUDQVLWLRQ FOLQLF LQ RUGHU WR LPSURYH WKLV H[SHULHQFH IRU ERWK SDWLHQW DQG WUHDWLQJ SK\VLFLDQV Material & Methods: 3DWLHQWV IURP WKH DJH RI \HDUV ROG DUH FRQVLGHUHG RQ DQ LQGLYLGXDO EDVLV IRU WUDQVLWLRQ WR DGROHVFHQW DQG DGXOW VHUYLFHV 7KRVH ZKR KDYHFOLQLFDOGLᚑFXOWLHVRUFRPSOH[LVVXHVDUHLQLWLDOO\VHHQDQGDVVHVVHGE\DQ DGROHVFHQWXURORJLVWLQDMRLQWDSSRLQWPHQWZLWKWKHSDWLHQWಬVSDHGLDWULFWHDP7KHVH UXQ LQ D PRQWKO\ WUDQVLWLRQ FOLQLF 7KHVH DUH SURORQJHG DSSRLQWPHQWV DOORZLQJ GHWDLOHGGLVFXVVLRQ7KHUHLVDUHYLHZRIFXUUHQWFOLQLFDOQRWHVDQGJHQHUDWLRQRI DWUDQVLWLRQVXPPDU\2QJRLQJWUHDWPHQWRULQYHVWLJDWLYHSODQVDUHPDGHDQGWKH QH[WUHYLHZLVVHWIRUWKHDGROHVFHQWFOLQLFLQWKHQHZLQVWLWXWLRQ Results: 7KXVIDUSDWLHQWVKDYHEHHQLGHQWLᚏHGDQGVHHQLQRXUWUDQVLWLRQFOLQLF
Eur Urol Suppl 2010;9(2):259