81. Nature of neurological deficits influences the treatment order preference for hip-spine syndrome

81. Nature of neurological deficits influences the treatment order preference for hip-spine syndrome

Proceedings of the 34th Annual Meeting of the North American Spine Society / The Spine Journal 19 (2019) S1−S58 vertebra (UIV+1, UIV+2) and one level ...

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Proceedings of the 34th Annual Meeting of the North American Spine Society / The Spine Journal 19 (2019) S1−S58 vertebra (UIV+1, UIV+2) and one level below the lower instrumented vertebra (LIV+1) were analyzed. Statistical analyses were conducted utilizing paired t-test, one-way/repeated-measures ANOVA, and Pearson’s correlation test. The statistical significance level was set at p<0.05. RESULTS: A total of 91 patients met our inclusion criteria. Mean age (&§ SD [range]) was 61.9 & 11.9; 55.6% of the patients were female. Median interval between the surgery and the secondary CT was 248 (180364) days. Volumetric BMD (&§ SD) in UIV+1 was 113.1 & § 32.6 mg/cm &>3 & preoperatively and 102.4 & § 32.2 mg/cm3 (percent change:-10.5 & § 12.6%) postoperatively (p <0.001). No correlation was observed between percent vBMD change in UIV+1 and interval between operation and postoperative CT (r=0.15, p=0.15). This trend of vBMD change was similar regardless of UIV level and number of fused level. The change of vBMDs in UIV+2 and LIV+1 appeared similar as UIV+1 (UIV +2: -11.9 & § 12.3%, p=0.19,LIV+1: -7.2 & § 20.7%, p=0.40). CONCLUSIONS: Posterior lumbar fusion surgery negatively affected the regional vBMDs measured by QCT in adjacent levels. BMDs in UIV+1, UIV+2, and LIV+1 were equally affected by the surgery. Our finding suggests that the postoperative decrease of regional BMDs in the lumbar spine dominantly occurs in the early postoperative phase (within 6 months) and a systemic effect has a greater role, rather than a regional mechanical one, in this postoperative BMD decline. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. https://doi.org/10.1016/j.spinee.2019.05.092

80. Bariatric surgery prior to elective anterior cervical discectomy and fusion in obese patients is associated with a reduced risk of 90-day postoperative complications and readmissions Azeem T. Malik, MBBS1, Sheldon Retchin, MD2, Wendy Xu, PhD2, Scott S. Strassels, PhD2, Elizabeth Yu, MD1, Safdar N. Khan, MD1; 1 The Ohio State University Wexner Medical Center, Columbus, OH, US; 2 Columbus, OH, US BACKGROUND CONTEXT: Obese patients, particularly those with a body mass index (BMI) ≥35 kg/m2, pose a major challenge for a spine surgeon. Though obesity has previously been shown to be linked with adverse outcomes following elective spine surgical procedures, the impact of prior bariatric surgery on altering postoperative outcomes following elective anterior cervical discectomy and fusions (ACDFs) has not been explored. PURPOSE: To evaluate whether bariatric surgery prior to ACDF in obese Medicare patients reduces the risk of experiencing adverse postoperative outcomes. STUDY DESIGN/SETTING: Retrospective review of 100% Medicare Claims Database. PATIENT SAMPLE: The PearlDiver program was used to query the 2007-2013 100% Medicare Standard Analytical Files (SAF100) for patients undergoing an elective ACDF using International Classification of Diseases 9th Edition (ICD-9) procedure codes 81.02. Records were filtered to include only those patients who underwent a 1- to 2-level surgery using ICD-9 procedure code 81.62. Only those patients receiving an ACDF due to degenerative spine pathologies were included in the study. Finally, patients who did not have active enrollment up to 2 years prior and 1 year after the surgery were excluded. A total of 121,382 patients undergoing an elective 1- to 2-level ACDF were included in the final cohort. OUTCOME MEASURES: ICD-9 diagnosis codes were used to identify patients having at least moderate/Class II obesity (V85.35-V85.45, V85.4 and 278.01) within the last 2 years prior to an ACDF. Based on previously published literature, ICD-9 procedure codes for high gastric bypass (44.31), laparoscopic gastroenterostomy (44.38), other gastroenterostomy without gastrectomy (44.39), laparoscopic gastroplasty (44.68), laparoscopic gastric restrictive procedure (44.95-44.98), insertion of gastric bubble (44.93), other repair of stomach (44.69), open and other partial gastrectomy (43.89), isolation of intestinal segment (45.50-45.51),

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intestinal anastomosis (45.90, 45.91), partial gastrectomy with anastomosis to esophagus (43.5), duodenum (43.6) and jejunum (43.7) and other operations on stomach, unspecified (44.99) being coded on the same day as an obesity code were used to categorize patients receiving a bariatric surgical procedure.Only those patients receiving a bariatric surgery within 2 years prior to an ACDF were included. The 2-year mark was chosen as an arbitrary value. The study cohort was divided into two groups: (1) obese ACDF patients (BMI ≥35) receiving a bariatric surgery procedure within two years prior to an ACDF and (2) obese ACDF patients (BMI ≥35) without a known history of a bariatric surgical procedure within the last 2 years. Primary outcomes included 90-day complications (wound, pulmonary, cardiac, sepsis, renal, deep venous thrombosis, pain and dysphagia), 90-day readmissions, 90-day and 1-year revision cervical fusions. METHODS: Multivariate analyses were used to assess the impact of prior bariatric surgery on 90-day outcomes following ACDF, after adjusting for age, gender, region and Elixhauser Co-morbidity Index. RESULTS: A total of 6,128 patients with a BMI >35kg/m2 underwent ACDF, of which 411 ACDF patients underwent a bariatric surgical procedure within the 2 years prior to an ACDF. Multivariate analysis adjusting for age, gender, region and Elixhauser Co-morbidity Index (ECI), demonstrated that a history of prior bariatric surgery was associated with a significantly reduced rate of 90-day pulmonary complications (6.6% vs 12.7%, OR 0.53 [95% CI 0.34-0.78]; p=0.002), cardiac complications (15.3% vs 24.2%, OR 0.69 [95% CI 0.51-0.92]; p=0.012), sepsis (9.5% vs 15.1%, OR 0.69 [95% CI 0.48-0.96]; p=0.035), renal complications (2.9% vs 7.1%, OR 0.54 [95% CI 0.28-0.94]; p=0.044) and 90-day readmissions (3.9% vs 8.0%, OR 0.53 [95% CI 0.30-0.85]; p=0.015). Prior bariatric surgery had no statistically significant impact on the rates of wound complications (p=0.325), deep venous thrombosis (p=0.176), pain complications (p=0.606), dysphagia (p=0.171), 90-day revision (p=0.875) and 1-year revisions (p=0.313). CONCLUSIONS: Surgery-induced weight loss prior to an ACDF in obese patients is associated with reduced 90-day complication and readmission rates. Orthopedic and bariatric surgeons should counsel obese patients on the benefits of bariatric surgery following ACDFs. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. https://doi.org/10.1016/j.spinee.2019.05.093

81. Nature of neurological deficits influences the treatment order preference for hip-spine syndrome Kirkham B. Wood, MD1, Stuart B. Goodman, MD, PhD2, Ning Liu, MD, MPH3, Paul F. Lachiewicz, MD4; 1 Stanford University School of Medicine Dept of Orthopedic Surgery, Redwood City, CA, US; 2 Stanford University School of Medicine, Redwood City, CA, US; 3 Stanford University, Redwood City, CA, US; 4 Duke University Department of Orthopaedic Surgery, Chapel Hill, NC, US BACKGROUND CONTEXT: With the aging of society, patients with concurrent degenerative lumbar disorders and hip osteoarthritis, also referred to as the "hip-spine syndrome," are frequently evaluated by both spine and arthroplasty surgeons. The decision-making can be straightforward in many but in others, the optimal treatment order—spine surgery or total hip arthroplasty (THA) first—remains unclear and complicated, especially when neurological deficits are involved. PURPOSE: To compare, in spine and arthroplasty surgeons respectively, the treatment order preference among four typical scenarios of hip-spine syndrome with different neurological symptoms. STUDY DESIGN/SETTING: Prospective survey at a professional society level. PATIENT SAMPLE: Eighty-eight experienced spine (37) and total hip arthroplasty (51) surgeons from the Scoliosis Research Society (SRS) and The Hip Society, respectively. OUTCOME MEASURES: Percentage of surgeons, in each specialty, choosing "spine first" in each scenario.

Refer to onsite annual meeting presentations and postmeeting proceedings for possible referenced figures and tables. Authors are responsible for accurately reporting disclosure and FDA device/drug status at time of abstract submission.

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Proceedings of the 34th Annual Meeting of the North American Spine Society / The Spine Journal 19 (2019) S1−S58

METHODS: Four fictional patients were devised to have concurrent degenerative lumbar disorders and painful hip osteoarthritis, with the primary neurological symptom in each scenario being (a) radicular leg pain, (b) neurogenic claudication, (c) leg weakness, and (d) myelopathy, respectively. A survey with history, physical examination, and radiographs was formulated and sent to clinical members of SRS and The Hip Society soliciting their treatment order preference—spine surgery or THA first—and their rationale. Surgeons’ choices, as measured by the percentage choosing "spine surgery first," were compared among the four scenarios and between the two specialties. Text-mining was used to summarize the rationale for decision-making by identifying the most frequently used words in surgeons’ comments. RESULTS: Responses were received from 37 (37/100, 37%) spine surgeons and 51 (51/101, 50%) arthroplasty surgeons across North America. In both specialties, the percentage choosing "spine first" varied in the same fashion among the four scenarios. Myelopathy, leg weakness, neurogenic claudication, and radicular pain, in that order, drove the decision-making toward "spine first" (97%, 73%, 46% and 8% of the spine surgeons and 86%, 45%, 33%, and 18% of the arthroplasty surgeons chose "spine first"). Only in the scenario of leg weakness did a significant disparity noted between the two specialties: spine surgeons were more sensitive to weakness than arthroplasty surgeons (73% vs 45% choosing "spine first," P=0.017). In both specialties, text-mining showed that the words that describe the symptoms or pathologies of the neurological deficits, such as "stenosis," "weakness," and "myelopathy," were most frequently used in surgeons’ comments in most scenarios except for that of radicular pain. CONCLUSIONS: The nature of neurological deficits influences the treatment order preference for hip-spine syndrome in both spine and arthroplasty surgeons, with myelopathy, weakness, neurogenic claudication, and radicular pain, in this order, driving the decision-making toward performing spine surgery first. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. https://doi.org/10.1016/j.spinee.2019.05.094

82. Bariatric surgery diminishes spinal symptoms in a morbidly obese population: a 2-year survivorship analysis of cervical and lumbar pathologies Peter G. Passias, MD1, Haddy Alas, BS2, Avery Brown, BS2, Cole Bortz, BA3, Katherine E. Pierce, BS3, Dennis Vasquez-Montes, MS, BA2, Bassel G. Diebo, MD4, Carl B. Paulino, MD5, John Afthinos, MD6, Michael C. Gerling, MD7; 1 NY Spine Institute, NYU Langone Health, New York, NY, US; 2 Department of Orthopedic Surgery, NYU Langone Orthopedic Hospital, NYU Langone Health, New York, NY, US; 3 New York, NY, US; 4 Department of Orthopaedic Surgery, SUNY Downstate Medical Center, Brooklyn, NY, US; 5 SUNY Downstate Medical Center, Brooklyn, NY, US; 6 Long Island Jewish Forest Hills, Forest Hills, NY, US; 7 NYU Langone, Brooklyn, Brooklyn, NY, US BACKGROUND CONTEXT: Bariatric surgery for morbid obesity helps to address common comorbidity burdens, including decreasing rates of myocardial infarction and stroke. The increased mechanical stresses on the spine caused by morbid obesity predispose patients to various spinal pathologies and are concerning for spinal surgeons, with previous studies suggesting poorer outcomes than the general population. The effects of bariatric surgery on diminishing spinal complaints or symptoms have yet to be elucidated in the literature. PURPOSE: To assess the rate in which various spinal symptoms diminish after bariatric surgery. STUDY DESIGN/SETTING: Retrospective analysis of the prospectively collected New York State Inpatient Database (NYSID) years (2004-2013). PATIENT SAMPLE: A total of 4,351 patients who underwent bariatric surgery with at least one identified spinal diagnosis present before bariatric surgery.

OUTCOME MEASURES: Time from bariatric surgery until disappearance of specific spinal complaint, percentage of unresolved spinal complaints with 2-year follow-up. METHODS: Retrospective analysis of the prospectively collected (NYSID) years 2004-2013. Patient linkage codes allow identification of multiple and return inpatient stays within the time frame analyzed (720 days). Inclusion criteria were bariatrics surgery patients with one or more visits prior to and after bariatric procedure (excluding pts with <30 days f/ u, spine surgery, or new post-bariatric spine pathology) for one of the following common cervical or lumbar spinal diagnoses, queried with ICD9CM codes: herniation, stenosis, spondylosis, disc degeneration, and spondylolisthesis. Time from bariatric surgery until the patient’s respective spinal diagnosis was no longer present was considered resolution of spinal symptoms. Kaplan-Meier survivorship curves assessed rates of resolution within each spinal diagnosis cohort. RESULTS: A total of 4,351 bariatric surgery pts with a preop spinal diagnosis by ICD-9 were analyzed. Lumbar pts: 1,049 had stenosis, 774 spondylosis, 648 degeneration, 249 spondylolisthesis, 72 disc herniation. Cervical pts: 581 disc herniation, 376 had stenosis, 366 spondylosis, 236 degeneration. Cumulative resolution rates at 90-day, 180-day, 360-day, and 720-day follow-up were as follows: lumbar stenosis (48%,67.6%,79%,91%), lumbar herniation (61%,77%,86%,93%), lumbar spondylosis (47%,65%,80%,93%), lumbar spondylolisthesis (37%,58%,70%,87%), lumbar degeneration (37%,56%,72%,86%). By cervical region: cervical stenosis (48%,70%,84%,94%), cervical herniation (39%,58%,74%,87%), cervical spondylosis (46%, 70%,83%, 94%), cervical degeneration (44%,64%,78%,89%). Lumbar herniation pts saw significantly higher 90d-resolution than cervical herniation pts (p<0.001). Cervical vs lumbar degeneration resolution rates did not differ @90d (p=0.058), but did @180d(p=0.034). Cervical and lumbar stenosis resolution was similar @90d & 180d, but cervical showed greater resolution by 1 year (p=0.036). CONCLUSIONS: Over 50% of bariatric patients diagnosed with a cervical or lumbar pathology before weight-loss surgery no longer sought inpatient care for their respective spinal diagnosis by 180 days postop. Lumbar herniation had significantly higher resolution than cervical herniation by 90d, whereas cervical degeneration and stenosis resolved at higher rates than corresponding lumbar pathologies by 180d and 1-year follow-up, respectively. FDA DEVICE/DRUG STATUS: This abstract does not discuss or include any applicable devices or drugs. https://doi.org/10.1016/j.spinee.2019.05.095

Wednesday, September 25, 2019 1:00 − 2:00 PM Cervical Spine Surgery III 83. Postoperative opioids and 1-year outcomes after spine surgery Catherine Carlile, MD1, Jeffrey M. Hills, MD2, Clinton J. Devin, MD3, Kristin R. Archer, PhD, DPT3, Jacquelyn S. Pennings, PhD3; 1 Nashville, TN, US; 2 Vanderbilt Orthopaedics, Nashville, TN, US; 3 Vanderbilt University Medical Center, Nashville, TN, US BACKGROUND CONTEXT: Opioid use prior to spine surgery has been associated with worse patient-reported outcomes, complications, and sustained postoperative opioid use. However, studies thus far have not assessed the relationship between opioid use in the initial postoperative period with long-term clinical outcomes and chronic postoperative opioid use. PURPOSE: Determine if longer duration and higher opioid dosage in the months following spine surgery is associated with 1-year patient-reported outcomes and chronic opioid use at 1 year. STUDY DESIGN/SETTING: Using data from our prospective clinical spine registry linked with opioid prescription data from our state’s prescription drug monitoring program, we conducted a longitudinal cohort study.

Refer to onsite annual meeting presentations and postmeeting proceedings for possible referenced figures and tables. Authors are responsible for accurately reporting disclosure and FDA device/drug status at time of abstract submission.