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832 Clinical correlation between incidentally detected bladder wall thickening on computed tomography scan and cystoscopy
Title
832
Clinical correlation between incidentally detected bladder wall thickening on computed tomography scan and cystoscopy Eur Urol Suppl 2015;14/2;e832
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Lee S.W., Kim T.H., Choi Y.H., Lee S.E., Park J.H., Jeong J.Y., Jung S.B., Sung H.H., Jeon H.G., Jeong B.C., Seo S.I., Jeon S.S., Choi HY., Kim J.J., Lee H.M. Samsung Medical Center, Sungkyunkwan University School of Medicine, Dept. of Urology, Seoul, South Korea INTRODUCTION & OBJECTIVES: The purpose of this study is to evaluate the relationship between bladder malignancy and incidentally detected bladder wall thickening(BWT) on computed tomography(CT) accompanying with cystoscopy. MATERIAL & METHODS: From January 2004 to November2013, 393 patients with BWT on CT were included and cystoscopy was done within 3 months from CT scan in a single institute. Patients with bladder malignancy history or BWT with bladder tumour lesion on CT were excluded. Patients were divided to focal group (n=48) and diffuse group (n=345) according to extent of BWT. Collected data were included age, gender, follow-up duration, history of hematuria, treatment for urinary tract infection and benign prostate hypertrophy (BPH), urine cytology and pathologic results. Multivariate analysis were performed to determine risk factors associated with bladder cancer incidence. RESULTS: The mean age of patients was 62.3 years and mean follow-up duration was 10.3 months. More than half of patients were male (63.1%, n=248) and of them, 90 patients (36.3%) were under treatment because of BPH. Most CT scan was examined because of microscopic (33.4%) or gross (61.1%) hematuria and common type of CT was CT urography (95.7%). In cystoscopic exam, hyperemic or suspicious lesion was found in 12 (25.0%) patients of focal group and 24 (7.0%) patients of diffuse group (p<0.001). Bladder tumour was detected in 7 (14.6%) in focal group and 17 (4.9%) patients in diffuse group respectively (p=0.009). Atypical cell in urine cytology were more frequent in focal group (12.5% vs. 6.7%) but, not significant (p=0.091). Transurethral resection of suspicious lesion or tumour was done 13 patients in focal group and 24 patients in diffuse group. Bladder malignancy was detected in total 17 (4.3%) patients and focal group was 5 patients (10.4%) and diffuse group were 12 patients (3.5%). Of them, rate of stromal invasion (T1 G1-3) was also high in focal group (80% vs 8.3%,p=0.036). Risk factors associated with bladder malignancy were atypical cell in urine cytology (p<0.001) and focal BWT (p=0.027) in univariate analysis. But only focal BWT was significant in multivariate analysis(p=0.007).
file:///S|/IM/EURSUP/2015%20EAU%20Abstracts/content/data/832.html[19/02/2015 08:21:38]
Title
CONCLUSIONS: Bladder malignancy was detected in 4.3% of patients with incidentally detected BWT on CT scan. Patients with focal BWT on CT showed more higher bladder malignancy detection rate and stromal invasion rate compared with diffuse BWT patients. Therefore more active evaluation was needed for patients with focal BWT on CT.
file:///S|/IM/EURSUP/2015%20EAU%20Abstracts/content/data/832.html[19/02/2015 08:21:38]
832
Clinical correlation between incidentally detected bladder wall thickening on computed tomography scan and cystoscopy Eur Urol Suppl 2015;14/2;e832
Print! Print!
Lee S.W., Kim T.H., Choi Y.H., Lee S.E., Park J.H., Jeong J.Y., Jung S.B., Sung H.H., Jeon H.G., Jeong B.C., Seo S.I., Jeon S.S., Choi HY., Kim J.J., Lee H.M. Samsung Medical Center, Sungkyunkwan University School of Medicine, Dept. of Urology, Seoul, South Korea INTRODUCTION & OBJECTIVES: The purpose of this study is to evaluate the relationship between bladder malignancy and incidentally detected bladder wall thickening(BWT) on computed tomography(CT) accompanying with cystoscopy. MATERIAL & METHODS: From January 2004 to November2013, 393 patients with BWT on CT were included and cystoscopy was done within 3 months from CT scan in a single institute. Patients with bladder malignancy history or BWT with bladder tumour lesion on CT were excluded. Patients were divided to focal group (n=48) and diffuse group (n=345) according to extent of BWT. Collected data were included age, gender, follow-up duration, history of hematuria, treatment for urinary tract infection and benign prostate hypertrophy (BPH), urine cytology and pathologic results. Multivariate analysis were performed to determine risk factors associated with bladder cancer incidence. RESULTS: The mean age of patients was 62.3 years and mean follow-up duration was 10.3 months. More than half of patients were male (63.1%, n=248) and of them, 90 patients (36.3%) were under treatment because of BPH. Most CT scan was examined because of microscopic (33.4%) or gross (61.1%) hematuria and common type of CT was CT urography (95.7%). In cystoscopic exam, hyperemic or suspicious lesion was found in 12 (25.0%) patients of focal group and 24 (7.0%) patients of diffuse group (p<0.001). Bladder tumour was detected in 7 (14.6%) in focal group and 17 (4.9%) patients in diffuse group respectively (p=0.009). Atypical cell in urine cytology were more frequent in focal group (12.5% vs. 6.7%) but, not significant (p=0.091). Transurethral resection of suspicious lesion or tumour was done 13 patients in focal group and 24 patients in diffuse group. Bladder malignancy was detected in total 17 (4.3%) patients and focal group was 5 patients (10.4%) and diffuse group were 12 patients (3.5%). Of them, rate of stromal invasion (T1 G1-3) was also high in focal group (80% vs 8.3%,p=0.036). Risk factors associated with bladder malignancy were atypical cell in urine cytology (p<0.001) and focal BWT (p=0.027) in univariate analysis. But only focal BWT was significant in multivariate analysis(p=0.007).
file:///S|/IM/EURSUP/2015%20EAU%20Abstracts/content/data/832.html[19/02/2015 08:21:38]
Title
CONCLUSIONS: Bladder malignancy was detected in 4.3% of patients with incidentally detected BWT on CT scan. Patients with focal BWT on CT showed more higher bladder malignancy detection rate and stromal invasion rate compared with diffuse BWT patients. Therefore more active evaluation was needed for patients with focal BWT on CT.
file:///S|/IM/EURSUP/2015%20EAU%20Abstracts/content/data/832.html[19/02/2015 08:21:38]