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8600892 New compounds having an immunizing activity
New Patents
4584194 INACTIVATED RABIES VACCINE FOR VETERINARY USE Edmund P Bass, Richard L Sharpee assigned to Norden Laboratories Inc The preparation of a vaccine for immunization of canine and feline animals from inactivated HCP-SAD strain of rabies virus is disclosed.
successive treatments with distinct aldehydes or tanning agents, as well as with proteinic substances, such as albumin, having dispersive properties. Finally the invention also provides a process for detecting the presence of rheumatoid factor in biological specimen which comprises contacting the latter with said reagent, whereby the response is positive or negative depending upon whether pattern hemagglutination or sedimentation of the cells of the complex is observed.
4585651 ACTIVE/PASSIVE IMMUNIZATION OF THE INTERNAL FEMALE REPRODUCTIVE ORGANS
8600892 NEW COMPOUNDS HAVING AN IMMUNIZING ACTIVITY
Lee R Beck, Charles F Flowers, Donald Cowsar, Albert C Tanquary assigned to Stolle Research & Development Corporation
Rudolf BIBER, Breitenfurterstrasse 487/2/5, A1238 Wien, Austria
Antibody or antigen containing microparticles for the active or passive immunization of the internal female reproductive organs, comprising: microparticles of an antigen or antibody incorporated in a matrix material which is biocompatible and biologically degradable, said microparticles capable of being transported after deposition in the vagina by the natural transport mechanism of the internal female reproductive organs across the cervix into the uterus.
Process for the preparation of new immunizing compounds of 2, 6-di)AD(monoalkylamino)acetyl amino)BDanthraquinone, by reacting 2,6 diaminoanthraquinone with alpha chloracetic acid chloride and reaction of bis-alphahalogenoacylamino anthraquinone thus obtained with methylamine or ethylamine. Also disclosed are compounds thus obtained or acid addition salts thereof, pharmaceutical compositions and utilization of said compounds as immunizing drugs.
4587222 REAGENT COMPRISING TREATED RED BLOOD CELLS AND METHODS FOR DETECTING RHEUMATOID FACTOR Rene Guffroy, La Madeleine, France assigned to Laboratories Polypharma A reagent for the detection of rheumatoid factor in tests in tubes or microplates. The reagent contains a complex formed from red blood cells and from antibodies soluble with respect to these red blood cells, and immunologicallyfixed to the latter, said reagent being both stable and capable in given dilution intervals to give rise to hemagglutination only subject to contacting it with detectable concentrations of rheumatoid factor. The invention also relates to a process for making said reagent which comprises subjecting red cells and the antibodies to be fixed thereon to
8600930 RETROVIRAL VACCINES AND VECTORS AND METHODS FOR THEIR CONSTRUCTION Harriet ROBINSON assigned to WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY Retroviruses and retrovirus vectors that either are or are not shed into eggs and therefore either do or do not undergo congenital transmission, and methods for making them. This invention is based on the discovery that the ability of exogenous avian leukosis viruses to undergo congenital transmission is determined by gag sequences of the viral genome.
4584194 INACTIVATED RABIES VACCINE FOR VETERINARY USE Edmund P Bass, Richard L Sharpee assigned to Norden Laboratories Inc The preparation of a vaccine for immunization of canine and feline animals from inactivated HCP-SAD strain of rabies virus is disclosed.
successive treatments with distinct aldehydes or tanning agents, as well as with proteinic substances, such as albumin, having dispersive properties. Finally the invention also provides a process for detecting the presence of rheumatoid factor in biological specimen which comprises contacting the latter with said reagent, whereby the response is positive or negative depending upon whether pattern hemagglutination or sedimentation of the cells of the complex is observed.
4585651 ACTIVE/PASSIVE IMMUNIZATION OF THE INTERNAL FEMALE REPRODUCTIVE ORGANS
8600892 NEW COMPOUNDS HAVING AN IMMUNIZING ACTIVITY
Lee R Beck, Charles F Flowers, Donald Cowsar, Albert C Tanquary assigned to Stolle Research & Development Corporation
Rudolf BIBER, Breitenfurterstrasse 487/2/5, A1238 Wien, Austria
Antibody or antigen containing microparticles for the active or passive immunization of the internal female reproductive organs, comprising: microparticles of an antigen or antibody incorporated in a matrix material which is biocompatible and biologically degradable, said microparticles capable of being transported after deposition in the vagina by the natural transport mechanism of the internal female reproductive organs across the cervix into the uterus.
Process for the preparation of new immunizing compounds of 2, 6-di)AD(monoalkylamino)acetyl amino)BDanthraquinone, by reacting 2,6 diaminoanthraquinone with alpha chloracetic acid chloride and reaction of bis-alphahalogenoacylamino anthraquinone thus obtained with methylamine or ethylamine. Also disclosed are compounds thus obtained or acid addition salts thereof, pharmaceutical compositions and utilization of said compounds as immunizing drugs.
4587222 REAGENT COMPRISING TREATED RED BLOOD CELLS AND METHODS FOR DETECTING RHEUMATOID FACTOR Rene Guffroy, La Madeleine, France assigned to Laboratories Polypharma A reagent for the detection of rheumatoid factor in tests in tubes or microplates. The reagent contains a complex formed from red blood cells and from antibodies soluble with respect to these red blood cells, and immunologicallyfixed to the latter, said reagent being both stable and capable in given dilution intervals to give rise to hemagglutination only subject to contacting it with detectable concentrations of rheumatoid factor. The invention also relates to a process for making said reagent which comprises subjecting red cells and the antibodies to be fixed thereon to
8600930 RETROVIRAL VACCINES AND VECTORS AND METHODS FOR THEIR CONSTRUCTION Harriet ROBINSON assigned to WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY Retroviruses and retrovirus vectors that either are or are not shed into eggs and therefore either do or do not undergo congenital transmission, and methods for making them. This invention is based on the discovery that the ability of exogenous avian leukosis viruses to undergo congenital transmission is determined by gag sequences of the viral genome.