99 The efficacy of tamsulosin in stone clearance after shock wave lithotripsy for renal calculi

99 The efficacy of tamsulosin in stone clearance after shock wave lithotripsy for renal calculi

Title 99 The efficacy of tamsulosin in stone clearance after shock wave lithotripsy for renal calculi Eur Urol Suppl 2015;14/2;e99           Print!...

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99

The efficacy of tamsulosin in stone clearance after shock wave lithotripsy for renal calculi Eur Urol Suppl 2015;14/2;e99          

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Teleb M. 1 , Dawod T.1 , Salem E. 1 , Ragab A. 1 , Shabana W.1 , Fawzi A. 1 , Kamel M. 1 , Wagdy A. 1 , Shalaby E. 2 , Kamel H.1 , Shahin A. 1 1 Zagazig

University, Faculty of Medicine, Dept. of Urology, Zagazig, Egypt, 2 Suez Canal University, Faculty of Medicine, Dept. of Urology,

Zagazig, Egypt INTRODUCTION & OBJECTIVES: To evaluate the efficacy of Tamsulosin 0.4 mg in fragments clearance after successful shock wave lithotripsy (SWL) for renal stones ≤ 2 cm. MATERIAL & METHODS: A prospective randomized study was conducted on 212 patients who underwent successful SWL (fragments < 4 mm) for single renal stone ≤ 2 cm in the period from March 2012 to April 2014. Included patients were divided into two groups; group I (n=106) was assigned to take an analgesic and anti-inflammatory only to facilitate clearance of SWL fragments, and group II (n=106) for which daily Tamsulosin 0.4 mg was added. Follow up of all patients 2 and 4 weeks after SWL was accomplished. The rate and timing of stone-free state achievement, the need for additional analgesia as well as occurrence of any complications were reported. RESULTS: The clearance rate for both stone categories of ≤ 1 cm and 1-2 cm pre-SWL maximal dimension was significantly better in group II (Tamsulosin) than that of group I (control) at 2 weeks of follow up after SWL (92.9% versus 67.7% and 83.3% versus 66.7% respectively). The overall clearance rate shows no statistically significant difference after 4 weeks of follow up (97.2% in group I versus 99.1% in group II). The need for additional analgesia and incidence of steinstrasse were significantly less in group II. CONCLUSIONS: Daily Tamsulosin 0.4 mg enhances clearance of stone fragments after SWL for renal stones and decrease the patients need for additional analgesics as well as the incidence of steinstrasse.

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