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A Case of Extra-Gastrointestinal Anisakidosis With Incidental Detection of a Live Larva During Laparoscopic Cystectomy
Accepted Manuscript A case of extra-gastrointestinal anisakidosis with incidental detection of a live larva during laparoscopic cystectomy Akihiko Ueda, M.D., Ayumi Tori, M.D., Tomoo Yoshimura, M.D., Ph.D., Kazuyo Kakui, M.D., Ph.D., Yukiyoshi Ishikawa, M.D. PII:
S1553-4650(16)31211-0
DOI:
10.1016/j.jmig.2016.12.003
Reference:
JMIG 3007
To appear in:
The Journal of Minimally Invasive Gynecology
Received Date: 13 October 2016 Revised Date:
22 November 2016
Accepted Date: 2 December 2016
Please cite this article as: Ueda A, Tori A, Yoshimura T, Kakui K, Ishikawa Y, A case of extragastrointestinal anisakidosis with incidental detection of a live larva during laparoscopic cystectomy, The Journal of Minimally Invasive Gynecology (2017), doi: 10.1016/j.jmig.2016.12.003. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT UEDA 1 1
Original
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Nov 20 2016
3
A case of extra-gastrointestinal anisakidosis with incidental detection of a live
5
larva during laparoscopic cystectomy
RI PT
4
6
Akihiko Ueda, M.D., Ayumi Tori, M.D., Tomoo Yoshimura, M.D., Ph.D., Kazuyo Kakui,
8
M.D., Ph.D., Yukiyoshi Ishikawa, M.D.
9
Department of Obstetrics and Gynecology, Saiseikai Noe Hospital, Osaka, Japan
M AN U
SC
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10 *Correspondence to:
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Akihiko Ueda M.D.
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Department of Obstetrics and Gynecology, Saiseikai Noe Hospital
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1-3-25, Furuichi, Joto-ku, Osaka 536-0001, Japan
15
Tel: +81-6-6932-0401 / Fax: +81-6-6932-7977
16
E- mail: [email protected]
EP
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Keywords: extra-gastrointestinal anisakidosis; laparoscopic surgery; round ligament
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Precis
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This is the first report of extra-gastrointestinal anisakidosis with detection of a live
21
larva during laparoscopic cystectomy.
22
Disclosure
23
The authors declare that they have no conflict of interest.
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ACCEPTED MANUSCRIPT UEDA 2 24
TEXT A 46-year-old woman, gravida 3 para 2, was diagnosed with enlarged bilateral ovarian
26
cysts during the outpatient follow-up of a 3-cm right ovarian cyst. She had eaten sushi four days
27
before surgery and had lower abdominal discomfort and mild diarrhea later. Magnetic resonance
28
imaging revealed bilateral endometriotic cysts. Laparoscopic bilateral ovarian cystectomies were
29
performed. Intraperitoneal observation revealed a live larva, covered with mucous material,
30
attached to the right round ligament. The larva was completely removed, and pathological
31
examination confirmed the diagnosis of anisakidosis (Fig. 1A−D).
SC
Extra-gastrointestinal anisakidosis is a rare occurrence, with larval migration into the
M AN U
32
RI PT
25
abdominal cavity and formation of granulomatous nodules on surrounding organs. This is the
34
first report of extra-gastrointestinal anisakidosis with laparoscopic detection of a live larva.
35
Complete surgical removal of the larva is curative, which can be confirmed by a decline in
36
serological tests (1−3), although unavailable in this case. Her postoperative follow-ups were
37
uneventful.
TE D
33
38 Reference
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1. Yoshimura H. Clinical patho-parasitology of extra-gastrointestinal anisakiasis. In: Ishikura H,
42 43 44 45
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41
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Kikuchi K, eds. Intestinal anisakiasis in Japan. Tokyo: Springer-Verlag; 1990; 145-54. 2. Ramanan P, Blumberg AK, Mathison B, Pritt BS. Parametrial Anisakidosis. J Clin Microbiol. 2013; 51:3430-3434.
3. Moore D, Girdwood R, Chiodini P. Treatment of anisakiasis with albendazole. Lancet. 2002; 360:54.
ACCEPTED MANUSCRIPT UEDA 3 Figure legends
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Figure 1. (A) A live larva covered with mucous material and attached to the right round ligament
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as seen during laparoscopy. (B, C) Complete removal of a larva (B) and mucus material (C). (D)
49
Pathological finding of the larva showing characteristic Y-shaped lateral cords in cross section
50
(hematoxylin and eosin, ×200).
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ACCEPTED MANUSCRIPT
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ACCEPTED MANUSCRIPT
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ACCEPTED MANUSCRIPT
S1553-4650(16)31211-0
DOI:
10.1016/j.jmig.2016.12.003
Reference:
JMIG 3007
To appear in:
The Journal of Minimally Invasive Gynecology
Received Date: 13 October 2016 Revised Date:
22 November 2016
Accepted Date: 2 December 2016
Please cite this article as: Ueda A, Tori A, Yoshimura T, Kakui K, Ishikawa Y, A case of extragastrointestinal anisakidosis with incidental detection of a live larva during laparoscopic cystectomy, The Journal of Minimally Invasive Gynecology (2017), doi: 10.1016/j.jmig.2016.12.003. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT UEDA 1 1
Original
2
Nov 20 2016
3
A case of extra-gastrointestinal anisakidosis with incidental detection of a live
5
larva during laparoscopic cystectomy
RI PT
4
6
Akihiko Ueda, M.D., Ayumi Tori, M.D., Tomoo Yoshimura, M.D., Ph.D., Kazuyo Kakui,
8
M.D., Ph.D., Yukiyoshi Ishikawa, M.D.
9
Department of Obstetrics and Gynecology, Saiseikai Noe Hospital, Osaka, Japan
M AN U
SC
7
10 *Correspondence to:
12
Akihiko Ueda M.D.
13
Department of Obstetrics and Gynecology, Saiseikai Noe Hospital
14
1-3-25, Furuichi, Joto-ku, Osaka 536-0001, Japan
15
Tel: +81-6-6932-0401 / Fax: +81-6-6932-7977
16
E- mail: [email protected]
EP
TE D
11
17
Keywords: extra-gastrointestinal anisakidosis; laparoscopic surgery; round ligament
19
Precis
20
This is the first report of extra-gastrointestinal anisakidosis with detection of a live
21
larva during laparoscopic cystectomy.
22
Disclosure
23
The authors declare that they have no conflict of interest.
AC C
18
ACCEPTED MANUSCRIPT UEDA 2 24
TEXT A 46-year-old woman, gravida 3 para 2, was diagnosed with enlarged bilateral ovarian
26
cysts during the outpatient follow-up of a 3-cm right ovarian cyst. She had eaten sushi four days
27
before surgery and had lower abdominal discomfort and mild diarrhea later. Magnetic resonance
28
imaging revealed bilateral endometriotic cysts. Laparoscopic bilateral ovarian cystectomies were
29
performed. Intraperitoneal observation revealed a live larva, covered with mucous material,
30
attached to the right round ligament. The larva was completely removed, and pathological
31
examination confirmed the diagnosis of anisakidosis (Fig. 1A−D).
SC
Extra-gastrointestinal anisakidosis is a rare occurrence, with larval migration into the
M AN U
32
RI PT
25
abdominal cavity and formation of granulomatous nodules on surrounding organs. This is the
34
first report of extra-gastrointestinal anisakidosis with laparoscopic detection of a live larva.
35
Complete surgical removal of the larva is curative, which can be confirmed by a decline in
36
serological tests (1−3), although unavailable in this case. Her postoperative follow-ups were
37
uneventful.
TE D
33
38 Reference
40
1. Yoshimura H. Clinical patho-parasitology of extra-gastrointestinal anisakiasis. In: Ishikura H,
42 43 44 45
AC C
41
EP
39
Kikuchi K, eds. Intestinal anisakiasis in Japan. Tokyo: Springer-Verlag; 1990; 145-54. 2. Ramanan P, Blumberg AK, Mathison B, Pritt BS. Parametrial Anisakidosis. J Clin Microbiol. 2013; 51:3430-3434.
3. Moore D, Girdwood R, Chiodini P. Treatment of anisakiasis with albendazole. Lancet. 2002; 360:54.
ACCEPTED MANUSCRIPT UEDA 3 Figure legends
47
Figure 1. (A) A live larva covered with mucous material and attached to the right round ligament
48
as seen during laparoscopy. (B, C) Complete removal of a larva (B) and mucus material (C). (D)
49
Pathological finding of the larva showing characteristic Y-shaped lateral cords in cross section
50
(hematoxylin and eosin, ×200).
AC C
EP
TE D
M AN U
SC
RI PT
46
AC C
EP
TE D
M AN U
SC
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ACCEPTED MANUSCRIPT
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