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A case of nasopharyngeal carcinoma presented with trismus
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Abstracts
The pathological type in the two rhabdomyosarcoma cases was embryonal. This type account for the majority of head and neck rhabdomyosarcomas in children. Pathological immunohistologic examination is useful for making this diagnosis. These two cases underwent chemotherapy and radiation. The patient with neuroblastoma had a metastasis primary pararenal lesion in the maxillary and ethmoidal sinuses. This diagnosis was made by biopsy of the maxillary sinus. In addition, urinary VMA and HVA levels were elevated and the diagnosis was supported by abdominal echo and CT examination. The patient underwent chemotherapy, radiation and surgery. We present the clinical courses of the three patients and discuss prognostic factors for both neoplasms, and the survival rate for the 25 years from 1965 to 1990 in our hospital. A case of nasopharyngeal carcinoma presented with trismus Takashi Chiba, Hisako Doi, Hiho Haeda, Uasao Yamamoto, Dqmrtment of’ Pediutrics, Nippon Medical School, Jupan
Yutaka Yoshida
Nasopharyngeal caricinoma is a rare malignant tumor during childhood. They are usually diagnosed in advanced locoregional stages. Common presenting symptoms are aural complaints, neck mass, and nasal complaints. We experienced a case of a 13-year-old boy presented with trismus. The boy initially visited a hospital because of trismus, which was then treated as temporpmandibular arthrosis. Cervical lymphadenopathy was noticed after 1 month, and a CT scan taken after 8 months revealed an extensive solid mass occupying the upper pharynx. On admission to our hospital, trismus, swelling of the right cheek, cervical lymphadenopathy, retraction of the right tympanic membrane and swelling of the bilateral inferior nasal concha were observed. Laboratory findings were non-specific and EB-YCA-IgA antibody and EB-EA-IgA antibody were negative while EB-YCA-IgG and EBNA were positive. MRI revealed a heterogenous mass invading the neighboring tissue. There was no evidence of distant metastases. The tumor was examined histologically through biopsy, and classified as lymphoepithelioma at Stage IV (T4N3MO). Irradiation and combined chemotherapy led to prompt diminution of tumor and lymphadenopathy. After 4 months bone metastases were found and at 22 months, local tumor recurrence occurred. However, the treatment was finally discontinued after 54 months and 42 months have passed without any sign of relapse. Head and Neck Tumors in Children Nobuaki Tsuchihashi, Nobuko Kawashiro, Fumiko Shishiyama, Hiroshi Kumanomidou Dqxwtmwt of’ Otoluryngology. Nutionul Children :v Hospital Eighty pediatric patients with head and neck tumors treated at our department over the 10 year period from 1987 to 1996, were reviewed. The subjects included 33 males and 47 females. The age at the first visit to our department ranged from 2 days to 15 years 3 months, with a mean of 3 years. The most common head and neck tumor in children was hemangioma (31 cases), followed by lymphangioma (17) malignant tumors (8) hamartoma (6) pleomorphic adenoma (3).
Abstracts
The pathological type in the two rhabdomyosarcoma cases was embryonal. This type account for the majority of head and neck rhabdomyosarcomas in children. Pathological immunohistologic examination is useful for making this diagnosis. These two cases underwent chemotherapy and radiation. The patient with neuroblastoma had a metastasis primary pararenal lesion in the maxillary and ethmoidal sinuses. This diagnosis was made by biopsy of the maxillary sinus. In addition, urinary VMA and HVA levels were elevated and the diagnosis was supported by abdominal echo and CT examination. The patient underwent chemotherapy, radiation and surgery. We present the clinical courses of the three patients and discuss prognostic factors for both neoplasms, and the survival rate for the 25 years from 1965 to 1990 in our hospital. A case of nasopharyngeal carcinoma presented with trismus Takashi Chiba, Hisako Doi, Hiho Haeda, Uasao Yamamoto, Dqmrtment of’ Pediutrics, Nippon Medical School, Jupan
Yutaka Yoshida
Nasopharyngeal caricinoma is a rare malignant tumor during childhood. They are usually diagnosed in advanced locoregional stages. Common presenting symptoms are aural complaints, neck mass, and nasal complaints. We experienced a case of a 13-year-old boy presented with trismus. The boy initially visited a hospital because of trismus, which was then treated as temporpmandibular arthrosis. Cervical lymphadenopathy was noticed after 1 month, and a CT scan taken after 8 months revealed an extensive solid mass occupying the upper pharynx. On admission to our hospital, trismus, swelling of the right cheek, cervical lymphadenopathy, retraction of the right tympanic membrane and swelling of the bilateral inferior nasal concha were observed. Laboratory findings were non-specific and EB-YCA-IgA antibody and EB-EA-IgA antibody were negative while EB-YCA-IgG and EBNA were positive. MRI revealed a heterogenous mass invading the neighboring tissue. There was no evidence of distant metastases. The tumor was examined histologically through biopsy, and classified as lymphoepithelioma at Stage IV (T4N3MO). Irradiation and combined chemotherapy led to prompt diminution of tumor and lymphadenopathy. After 4 months bone metastases were found and at 22 months, local tumor recurrence occurred. However, the treatment was finally discontinued after 54 months and 42 months have passed without any sign of relapse. Head and Neck Tumors in Children Nobuaki Tsuchihashi, Nobuko Kawashiro, Fumiko Shishiyama, Hiroshi Kumanomidou Dqxwtmwt of’ Otoluryngology. Nutionul Children :v Hospital Eighty pediatric patients with head and neck tumors treated at our department over the 10 year period from 1987 to 1996, were reviewed. The subjects included 33 males and 47 females. The age at the first visit to our department ranged from 2 days to 15 years 3 months, with a mean of 3 years. The most common head and neck tumor in children was hemangioma (31 cases), followed by lymphangioma (17) malignant tumors (8) hamartoma (6) pleomorphic adenoma (3).